BLASTX 7.6.2

Query= UN95974 /QuerySize=889
        (888 letters)

Database: Uniprot/SwissProt;
          537,505 sequences; 190,795,139 total letters
                                                                  Score    E
Sequences producing significant alignments:                       (bits) Value

sp|Q29451|MA2B1_BOVIN Lysosomal alpha-mannosidase OS=Bos taurus ...    126   2e-028
sp|Q8VHC8|MA2B1_CAVPO Lysosomal alpha-mannosidase OS=Cavia porce...    126   2e-028
sp|O46432|MA2B1_FELCA Lysosomal alpha-mannosidase OS=Felis catus...    126   2e-028
sp|O00754|MA2B1_HUMAN Lysosomal alpha-mannosidase OS=Homo sapien...    126   4e-028
sp|P34098|MANA_DICDI Lysosomal alpha-mannosidase OS=Dictyosteliu...    124   8e-028
sp|Q60HE9|MA2B1_MACFA Lysosomal alpha-mannosidase OS=Macaca fasc...    122   4e-027
sp|O09159|MA2B1_MOUSE Lysosomal alpha-mannosidase OS=Mus musculu...    119   4e-026
sp|Q8BRK9|MA2A2_MOUSE Alpha-mannosidase 2x OS=Mus musculus GN=Ma...     52   7e-006

>sp|Q29451|MA2B1_BOVIN Lysosomal alpha-mannosidase OS=Bos taurus GN=MAN2B1 PE=1
        SV=3

          Length = 999

 Score =  126 bits (316), Expect = 2e-028
 Identities = 61/102 (59%), Positives = 74/102 (72%)
 Frame = -2

Query: 584 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 405
           Y+T   V  D LNVHLV HTHDDVGWLKTVDQY+ G  N+IQ A VQ +LDS++ +LL +
Sbjct:  53 YKTCPKVKPDMLNVHLVPHTHDDVGWLKTVDQYFYGIYNNIQPAGVQYILDSVISSLLAN 112

Query: 404 KNRKFVYVEQAFFQRWWRDQSEATQTIVKALVSSGQLELMVG 279
             R+F+YVE AFF RWWR Q+ ATQ IV+ LV  G+LE   G
Sbjct: 113 PTRRFIYVEIAFFSRWWRQQTNATQKIVRELVRQGRLEFANG 154

>sp|Q8VHC8|MA2B1_CAVPO Lysosomal alpha-mannosidase OS=Cavia porcellus GN=MAN2B1
        PE=1 SV=1

          Length = 1007

 Score =  126 bits (316), Expect = 2e-028
 Identities = 61/102 (59%), Positives = 72/102 (70%)
 Frame = -2

Query: 584 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 405
           YET   V    LNVHLVAHTHDDVGWLKTVDQYY G +N +Q A VQ +LDS++ ALL +
Sbjct:  50 YETCPMVQPGMLNVHLVAHTHDDVGWLKTVDQYYWGIHNDLQQAGVQYILDSVISALLAE 109

Query: 404 KNRKFVYVEQAFFQRWWRDQSEATQTIVKALVSSGQLELMVG 279
             R+FVYVE AFF RWW  Q+  TQ +V+ LV  G+LE   G
Sbjct: 110 PTRRFVYVEMAFFSRWWHQQTNETQEVVRRLVRQGRLEFANG 151

>sp|O46432|MA2B1_FELCA Lysosomal alpha-mannosidase OS=Felis catus GN=MAN2B1 PE=2
        SV=1

          Length = 1007

 Score =  126 bits (316), Expect = 2e-028
 Identities = 60/102 (58%), Positives = 74/102 (72%)
 Frame = -2

Query: 584 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 405
           YET   V  D LNVHLVAHTHDDVGWLKTVDQY+ G +N +Q A VQ +LDS++ +LL +
Sbjct:  53 YETCPMVHPDMLNVHLVAHTHDDVGWLKTVDQYFYGIHNDVQHAGVQYILDSVISSLLVE 112

Query: 404 KNRKFVYVEQAFFQRWWRDQSEATQTIVKALVSSGQLELMVG 279
             R+F+YVE AFF RWW  Q+ ATQ +V+ LV  G+LE   G
Sbjct: 113 PTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFANG 154

>sp|O00754|MA2B1_HUMAN Lysosomal alpha-mannosidase OS=Homo sapiens GN=MAN2B1
        PE=1 SV=3

          Length = 1011

 Score =  126 bits (314), Expect = 4e-028
 Identities = 60/102 (58%), Positives = 72/102 (70%)
 Frame = -2

Query: 584 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 405
           YET   V  + LNVHL+ HTHDDVGWLKTVDQY+ G  N IQ A VQ +LDS++ ALL D
Sbjct:  52 YETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLAD 111

Query: 404 KNRKFVYVEQAFFQRWWRDQSEATQTIVKALVSSGQLELMVG 279
             R+F+YVE AFF RWW  Q+ ATQ +V+ LV  G+LE   G
Sbjct: 112 PTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFANG 153

>sp|P34098|MANA_DICDI Lysosomal alpha-mannosidase OS=Dictyostelium discoideum
        GN=manA PE=1 SV=2

          Length = 1010

 Score =  124 bits (311), Expect = 8e-028
 Identities = 60/91 (65%), Positives = 68/91 (74%)
 Frame = -2

Query: 551 LNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRDKNRKFVYVEQA 372
           LNVH+VAHTHDDVGWLKTVD+YY GSN SI  A VQ  LD+ +  LL +  RKF+YVE A
Sbjct:  42 LNVHIVAHTHDDVGWLKTVDEYYYGSNMSIAFAGVQYTLDTAITCLLANPERKFIYVEIA 101

Query: 371 FFQRWWRDQSEATQTIVKALVSSGQLELMVG 279
           FFQRWW +QS   Q IVK LV SGQLE + G
Sbjct: 102 FFQRWWDEQSTTMQNIVKGLVESGQLEFING 132

>sp|Q60HE9|MA2B1_MACFA Lysosomal alpha-mannosidase OS=Macaca fascicularis
        GN=MAN2B1 PE=2 SV=1

          Length = 1012

 Score =  122 bits (305), Expect = 4e-027
 Identities = 59/102 (57%), Positives = 71/102 (69%)
 Frame = -2

Query: 584 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 405
           YET   V  + LNVHLV HTHDDVGWLKTVDQY+ G  N IQ A VQ +LDS++ ALL D
Sbjct:  53 YETCPTVQPNILNVHLVPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLAD 112

Query: 404 KNRKFVYVEQAFFQRWWRDQSEATQTIVKALVSSGQLELMVG 279
             R+F+YVE AFF RWW  Q+ A + +V+ LV  G+LE   G
Sbjct: 113 PTRRFIYVEIAFFSRWWHQQTNAMREVVRDLVRQGRLEFANG 154

>sp|O09159|MA2B1_MOUSE Lysosomal alpha-mannosidase OS=Mus musculus GN=Man2b1
        PE=2 SV=4

          Length = 1013

 Score =  119 bits (296), Expect = 4e-026
 Identities = 56/102 (54%), Positives = 70/102 (68%)
 Frame = -2

Query: 584 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 405
           Y+T        LNVHL+ HTHDDVGWLKTVDQYY G  + +Q A VQ +LDS+V +LL  
Sbjct:  52 YKTCPPTKPGMLNVHLLPHTHDDVGWLKTVDQYYYGILSDVQHASVQYILDSVVSSLLEK 111

Query: 404 KNRKFVYVEQAFFQRWWRDQSEATQTIVKALVSSGQLELMVG 279
             R+F+YVE AFF RWW+ Q+ ATQ  V+ LV  G+LE + G
Sbjct: 112 PTRRFIYVEMAFFSRWWKQQTSATQDAVRNLVRQGRLEFVNG 153

>sp|Q8BRK9|MA2A2_MOUSE Alpha-mannosidase 2x OS=Mus musculus GN=Man2a2 PE=2 SV=2

          Length = 1152

 Score =  52 bits (122), Expect = 7e-006
 Identities = 22/56 (39%), Positives = 36/56 (64%)
 Frame = -2

Query: 446 QNVLDSLVPALLRDKNRKFVYVEQAFFQRWWRDQSEATQTIVKALVSSGQLELMVG 279
           Q++L+S+V  L  D  R+F++ E +FF +WW + S   +  V+ LV +GQLE+  G
Sbjct: 193 QHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATG 248

  Database: Uniprot/SwissProt
    Posted date:  Thu Sep 27 17:53:50 2012
  Number of letters in database: 190,795,139
  Number of sequences in database:  537,505

Lambda     K     H
   0.267   0.041    0.140
Gapped
Lambda     K     H
   0.267   0.041    0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 181,605,474,615
Number of Sequences: 537505
Number of Extensions: 181605474615
Number of Successful Extensions: 1062874541
Number of sequences better than 0.0: 0