SwissProt blast output of UN95972
BLASTX 7.6.2
Query= UN95972 /QuerySize=2454
(2453 letters)
Database: Uniprot/SwissProt;
537,505 sequences; 190,795,139 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O09159|MA2B1_MOUSE Lysosomal alpha-mannosidase OS=Mus musculu... 498 8e-140
sp|P34098|MANA_DICDI Lysosomal alpha-mannosidase OS=Dictyosteliu... 451 1e-125
sp|Q8VHC8|MA2B1_CAVPO Lysosomal alpha-mannosidase OS=Cavia porce... 429 6e-119
sp|Q29451|MA2B1_BOVIN Lysosomal alpha-mannosidase OS=Bos taurus ... 424 2e-117
sp|O00754|MA2B1_HUMAN Lysosomal alpha-mannosidase OS=Homo sapien... 423 4e-117
sp|O46432|MA2B1_FELCA Lysosomal alpha-mannosidase OS=Felis catus... 422 7e-117
sp|Q60HE9|MA2B1_MACFA Lysosomal alpha-mannosidase OS=Macaca fasc... 418 1e-115
sp|Q54KN4|MANF_DICDI Alpha-mannosidase F OS=Dictyostelium discoi... 252 1e-065
sp|Q28949|MA2B2_PIG Epididymis-specific alpha-mannosidase OS=Sus... 203 7e-051
sp|Q9Y2E5|MA2B2_HUMAN Epididymis-specific alpha-mannosidase OS=H... 132 1e-029
sp|Q5RDJ3|MA2B2_PONAB Epididymis-specific alpha-mannosidase OS=P... 132 1e-029
sp|Q54YC4|MAND_DICDI Alpha-mannosidase D OS=Dictyostelium discoi... 130 7e-029
sp|P27046|MA2A1_MOUSE Alpha-mannosidase 2 OS=Mus musculus GN=Man... 129 2e-028
sp|Q16706|MA2A1_HUMAN Alpha-mannosidase 2 OS=Homo sapiens GN=MAN... 127 6e-028
sp|P28494|MA2A1_RAT Alpha-mannosidase 2 (Fragment) OS=Rattus nor... 127 6e-028
sp|O54782|MA2B2_MOUSE Epididymis-specific alpha-mannosidase OS=M... 126 1e-027
sp|Q8BRK9|MA2A2_MOUSE Alpha-mannosidase 2x OS=Mus musculus GN=Ma... 125 2e-027
sp|P49641|MA2A2_HUMAN Alpha-mannosidase 2x OS=Homo sapiens GN=MA... 122 1e-026
sp|Q54YF7|MANB_DICDI Alpha-mannosidase B OS=Dictyostelium discoi... 112 1e-023
sp|Q55ER0|MANC_DICDI Alpha-mannosidase C OS=Dictyostelium discoi... 110 6e-023
>sp|O09159|MA2B1_MOUSE Lysosomal alpha-mannosidase OS=Mus musculus GN=Man2b1
PE=2 SV=4
Length = 1013
Score = 498 bits (1282), Expect = 8e-140
Identities = 287/703 (40%), Positives = 398/703 (56%), Gaps = 46/703 (6%)
Frame = -2
Query: 2149 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 1970
Y+T LNVHL+ HTHDDVGWLKTVDQYY G + +Q A VQ +LDS+V +LL
Sbjct: 52 YKTCPPTKPGMLNVHLLPHTHDDVGWLKTVDQYYYGILSDVQHASVQYILDSVVSSLLEK 111
Query: 1969 KNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQ 1790
R+F+YVE AFF RWW+ Q+ AT++ V+ V G+LE +NGGW M+DEAA HY ++DQ
Sbjct: 112 PTRRFIYVEMAFFSRWWKQQTSATQDAVRNLVRQGRLEFVNGGWVMNDEAATHYGAIVDQ 171
Query: 1789 TTYGHKFIKQQF--NVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRK 1616
T G +F++ F + PR+ W IDPFGHS QA L A++GFD F GRIDYQD+ RK
Sbjct: 172 MTLGLRFLQDTFGSDGLPRVAWHIDPFGHSREQASLF-AQMGFDGFFLGRIDYQDKLNRK 230
Query: 1615 GDKRLEVIWRASKSL-GSSSQIFAGAFPENYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQ 1439
R+E +WRAS SL ++ +F G P NY PP ++V V D+ ++N +
Sbjct: 231 KKLRMEELWRASDSLEPPAADLFTGVLPNNYNPPKYLCWDVLCTDPPVVDNPRSPEFNAK 290
Query: 1438 ERVNDFVAAAVSQANITRSNHVMWTMGTDFKYQYAESWFRNMDKLIHYVN----KDGRVN 1271
VN F+ A SQ R+NH + TMG+DF Y+ A WF+NMDKLI VN V+
Sbjct: 291 TLVNYFLKLASSQKGFYRTNHTVMTMGSDFHYENANMWFKNMDKLIRLVNAQQVNGSLVH 350
Query: 1270 ALYSTPSIYTDAKYAETDSWPLKEEDYFPYASDINAYWTGYFTSRPGLKGYVRMLSGYYL 1091
LYSTP+ Y +W +KE+D+FPYA + +WTGYF+SRP LK Y R+ +
Sbjct: 351 VLYSTPTCYLWELNKANLTWTVKEDDFFPYADGPHMFWTGYFSSRPALKRYERLSYNFLQ 410
Query: 1090 AARQLEVLKG-RNKAGP--TTDS--LGDALGIAQHHDAVSGTSQQHVANDYAKRLAISHK 926
QLE L G GP + DS L +A+ + QHHDAVSGT++Q+V NDYA++LA
Sbjct: 411 VCNQLEALVGPEANVGPYGSGDSAPLQEAMAVLQHHDAVSGTARQNVVNDYARQLAAGWG 470
Query: 925 EAEVVVAESLAGMVSSKSGHESSATHFQQCPLLNISYCPPTEADLSSGKKLVVVVYNSLG 746
EV+V+ +LA + K +F C LNIS CP ++ + ++ V +YN LG
Sbjct: 471 PCEVLVSNALARLSHYKQ-------NFSFCRELNISICPVSQ----TSERFQVTLYNPLG 519
Query: 745 WKRSDVIRLPVVSDNIAVYDSSGKQVESQLLPVVKDSIALRNYYATAYTGKSPSSTPKFT 566
K ++RLPV N V D K + S + + + +YY+ Y ++
Sbjct: 520 RKVDQMVRLPVYEGNFIVKDPHDKNISSNV-------VMVPSYYSETY---------QWE 563
Query: 565 LAFTASVPPLGFSTYTIQSTKKPASNFVKQALYKHTRIGKGG--VEVGTGNLKLIYSKSE 392
L F ASVP LGFSTY++ K N L R K + + ++ +
Sbjct: 564 LLFPASVPALGFSTYSV--AKMSDLNHQAHNLLSRPRKHKSHHVLVIENKYMRATFDSGT 621
Query: 391 GKLSQYVNSRSSIEASVSQSYLYY-AGFDGTTGLQASGAYIFRPNGSYSIG-SQEQNITV 218
G L + N ++ VSQ + +Y A QASGAYIFRPN I S+ I++
Sbjct: 622 GLLMKIENLEQNLSLPVSQGFFWYNASVGDEESSQASGAYIFRPNVGKPIPVSRWAQISL 681
Query: 217 LRGPIYEEVHQKINPWIYQITRVYKNKEHAEVEFTVGPIPIED 89
++ + +EVHQ + W Q+ R+YK + H E+E+TVGPIP+ D
Sbjct: 682 VKTALVQEVHQNFSAWCSQVIRLYKGQRHLELEWTVGPIPVRD 724
>sp|P34098|MANA_DICDI Lysosomal alpha-mannosidase OS=Dictyostelium discoideum
GN=manA PE=1 SV=2
Length = 1010
Score = 451 bits (1159), Expect = 1e-125
Identities = 239/500 (47%), Positives = 314/500 (62%), Gaps = 19/500 (3%)
Frame = -2
Query: 2116 LNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRDKNRKFVYVEQA 1937
LNVH+VAHTHDDVGWLKTVD+YY GSN SI A VQ LD+ + LL + RKF+YVE A
Sbjct: 42 LNVHIVAHTHDDVGWLKTVDEYYYGSNMSIAFAGVQYTLDTAITCLLANPERKFIYVEIA 101
Query: 1936 FFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQTTYGHKFIKQQ 1757
FFQRWW +QS +NIVKG V SGQLE INGG+CM+DEA +Y D IDQ T GH+F+ +
Sbjct: 102 FFQRWWDEQSTTMQNIVKGLVESGQLEFINGGYCMNDEATTYYDDTIDQMTLGHQFLWEN 161
Query: 1756 FNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRKGDKRLEVIWRASK 1577
F V P+IGW IDPFGHSA QA + G ++GFD+ GR+DYQD R +K++E +WR+++
Sbjct: 162 FGVMPKIGWHIDPFGHSATQARIFG-QLGFDAFIIGRMDYQDIEARLENKQMEFMWRSTQ 220
Query: 1576 SLGSSSQIFAGAFPENYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQERVNDFVAAAVSQA 1397
S +Q+F Y P GF FE DD +QDD NLFD NV R F A+ A
Sbjct: 221 ST-PENQVFTSVLRAMYCTPDGFNFEQGDDP--IQDDPNLFDNNVDSRAEQFTQVALEYA 277
Query: 1396 NITRSNHVMWTMGTDFKYQYAESWFRNMDKLIHYVNKDG---RVNALYSTPSIYTDAKYA 1226
R+N+V+ G DF Y A+ +++N+DKLI ++N + +N LYSTPSIY DA
Sbjct: 278 THYRTNNVLIPFGCDFAYLNAQMYYKNIDKLIAHINSNPDKYGLNLLYSTPSIYIDAVND 337
Query: 1225 ETDSWPLKEEDYFPYASDINAYWTGYFTSRPGLKGYVRMLSGYYLAARQLEVLKGRNKAG 1046
W +K +D FPYA + +YWTGYF SRP LKGYVR + Q+ V
Sbjct: 338 ANLVWEVKTDDLFPYADNEFSYWTGYFVSRPALKGYVRQNNALLHVVEQMLVTSSNLMPS 397
Query: 1045 PTTDSLGD-------ALGIAQHHDAVSGTSQQHVANDYAKRLAISHKEAEVVVAESLAGM 887
++ L D +GIAQHHDAVSGT QQHVA+DYA+RL+I + A + ++ G
Sbjct: 398 SRSEQLVDDIVIMREVMGIAQHHDAVSGTEQQHVADDYAERLSIGNC-ASLETINTVVGT 456
Query: 886 VSSKSGHESSAT---HFQQCPLLNISYCPPTEADLSSGKKLVVVVYNSLGWKRSDVIRLP 716
+ + +G+ SA CPLLN S CP T+ LSSG + V++YNSL W R++ +R+P
Sbjct: 457 LLTANGNSKSAAATPTISFCPLLNQSICPATD-PLSSGTSVPVLIYNSLSWTRNEPVRIP 515
Query: 715 VVSDNIAVYDSSGKQVESQL 656
+ N+ V SS + SQ+
Sbjct: 516 IPIANVTVTSSSNGSITSQV 535
>sp|Q8VHC8|MA2B1_CAVPO Lysosomal alpha-mannosidase OS=Cavia porcellus GN=MAN2B1
PE=1 SV=1
Length = 1007
Score = 429 bits (1102), Expect = 6e-119
Identities = 231/511 (45%), Positives = 312/511 (61%), Gaps = 24/511 (4%)
Frame = -2
Query: 2149 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 1970
YET V LNVHLVAHTHDDVGWLKTVDQYY G +N +Q A VQ +LDS++ ALL +
Sbjct: 50 YETCPMVQPGMLNVHLVAHTHDDVGWLKTVDQYYWGIHNDLQQAGVQYILDSVISALLAE 109
Query: 1969 KNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQ 1790
R+FVYVE AFF RWW Q+ T+ +V+ V G+LE NGGW M+DEAA HY ++DQ
Sbjct: 110 PTRRFVYVEMAFFSRWWHQQTNETQEVVRRLVRQGRLEFANGGWVMNDEAATHYGAIVDQ 169
Query: 1789 TTYGHKFIKQQF--NVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRK 1616
T G +F++ F + PR+ W IDPFGHS QA L A++GFD +FFGRIDYQD+ RK
Sbjct: 170 MTLGLRFLEDTFGSDGRPRVAWHIDPFGHSREQASLF-AQMGFDGVFFGRIDYQDKLVRK 228
Query: 1615 GDKRLEVIWRASKSL-GSSSQIFAGAFPENYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQ 1439
+ +E++WRAS SL ++ +F G P NY PP G ++V V DD +YN +
Sbjct: 229 KRREMELVWRASASLKAPAADLFTGVLPNNYGPPEGLCWDVLCADPPVVDDPRSPEYNAK 288
Query: 1438 ERVNDFVAAAVSQANITRSNHVMWTMGTDFKYQYAESWFRNMDKLIHYVN----KDGRVN 1271
+ V+ F+ A +Q R+NH + TMG+DF+Y+ A +WF+N+DKLI VN RV+
Sbjct: 289 KLVSYFLQLATAQGRYYRTNHTVMTMGSDFQYENANTWFKNLDKLIQLVNMQQANGSRVH 348
Query: 1270 ALYSTPSIYTDAKYAETDSWPLKEEDYFPYASDINAYWTGYFTSRPGLKGYVRMLSGYYL 1091
LYSTP+ Y +WP+KE+D+FPYA + +WTGYF+SRP LK Y R+ +
Sbjct: 349 VLYSTPACYLWELNKANLTWPVKEDDFFPYADGPHMFWTGYFSSRPALKRYERLSYNFLQ 408
Query: 1090 AARQLEVLKG-RNKAGP----TTDSLGDALGIAQHHDAVSGTSQQHVANDYAKRLAISHK 926
QLE G GP + L A+ + QHHDAVSGTS+QHVA+DYA++LA
Sbjct: 409 VCNQLEAQVGPAANVGPYGHGDSSPLNQAMAVLQHHDAVSGTSKQHVADDYARQLAAGWG 468
Query: 925 EAEVVVAESLAGMVSSKSGHESSATHFQQCPLLNISYCPPTEADLSSGKKLVVVVYNSLG 746
EV+++ +LA + SK F C LNIS CP ++ + ++ V+VYN LG
Sbjct: 469 PCEVLLSNALAKLSGSKE-------TFLFCRDLNISICPFSQ----TSERFQVLVYNPLG 517
Query: 745 WKRSDVIRLPVVSDNIAVYDSSGKQVESQLL 653
K ++RLPV + D V S ++
Sbjct: 518 RKVDRMVRLPVRKGLFLIKDPGNNTVPSTVV 548
>sp|Q29451|MA2B1_BOVIN Lysosomal alpha-mannosidase OS=Bos taurus GN=MAN2B1 PE=1
SV=3
Length = 999
Score = 424 bits (1089), Expect = 2e-117
Identities = 232/514 (45%), Positives = 313/514 (60%), Gaps = 25/514 (4%)
Frame = -2
Query: 2149 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 1970
Y+T V D LNVHLV HTHDDVGWLKTVDQY+ G N+IQ A VQ +LDS++ +LL +
Sbjct: 53 YKTCPKVKPDMLNVHLVPHTHDDVGWLKTVDQYFYGIYNNIQPAGVQYILDSVISSLLAN 112
Query: 1969 KNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQ 1790
R+F+YVE AFF RWWR Q+ AT+ IV+ V G+LE NGGW M+DEA HY +IDQ
Sbjct: 113 PTRRFIYVEIAFFSRWWRQQTNATQKIVRELVRQGRLEFANGGWVMNDEATTHYGAIIDQ 172
Query: 1789 TTYGHKFIKQQF--NVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRK 1616
T +F+++ F + PR+ W IDPFGHS QA L A++GFD FFGR+DYQD+ RK
Sbjct: 173 MTLRLRFLEETFGSDGRPRVAWHIDPFGHSREQASLF-AQMGFDGFFFGRLDYQDKKVRK 231
Query: 1615 GDKRLEVIWRASKSL-GSSSQIFAGAFPENYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQ 1439
++E +WRAS SL ++ +F P Y PP G +++ K V +D +YN +
Sbjct: 232 KTLQMEQVWRASTSLKPPTADLFTSVLPNMYNPPEGLCWDMLCADKPVVEDTRSPEYNAK 291
Query: 1438 ERVNDFVAAAVSQANITRSNHVMWTMGTDFKYQYAESWFRNMDKLIHYVNKDG-----RV 1274
E V F+ A Q + R+ H + TMG+DF+Y+ A +WF+N+DKLI VN RV
Sbjct: 292 ELVRYFLKLATDQGKLYRTKHTVMTMGSDFQYENANTWFKNLDKLIQLVNAQQRANGIRV 351
Query: 1273 NALYSTPSIYTDAKYAETDSWPLKEEDYFPYASDINAYWTGYFTSRPGLKGYVRMLSGYY 1094
N LYSTP+ Y SW +K++D+FPYA +WTGYF+SRP LK Y R+ +
Sbjct: 352 NVLYSTPACYLWELNKANLSWSVKKDDFFPYADGPYMFWTGYFSSRPALKRYERLSYNFL 411
Query: 1093 LAARQLEVLKG-RNKAGP--TTDS--LGDALGIAQHHDAVSGTSQQHVANDYAKRLAISH 929
QLE L G GP + DS L +A+ + QHHDAVSGTS+QHVANDYA++L+
Sbjct: 412 QVCNQLEALAGPAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLSEGW 471
Query: 928 KEAEVVVAESLAGMVSSKSGHESSATHFQQCPLLNISYCPPTEADLSSGKKLVVVVYNSL 749
+ EV+++ +LA + K F C LNIS CP T+ + ++ V+VYN L
Sbjct: 472 RPCEVLMSNALAHLSGLKE-------DFAFCRKLNISICPLTQ----TAERFQVIVYNPL 520
Query: 748 GWKRSDVIRLPVVSDNIAVYDSSGKQVESQLLPV 647
G K ++RLPV V D GK V S ++ +
Sbjct: 521 GRKVDWMVRLPVSKHVYLVKDPGGKIVPSDVVTI 554
>sp|O00754|MA2B1_HUMAN Lysosomal alpha-mannosidase OS=Homo sapiens GN=MAN2B1
PE=1 SV=3
Length = 1011
Score = 423 bits (1086), Expect = 4e-117
Identities = 229/511 (44%), Positives = 311/511 (60%), Gaps = 24/511 (4%)
Frame = -2
Query: 2149 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 1970
YET V + LNVHL+ HTHDDVGWLKTVDQY+ G N IQ A VQ +LDS++ ALL D
Sbjct: 52 YETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLAD 111
Query: 1969 KNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQ 1790
R+F+YVE AFF RWW Q+ AT+ +V+ V G+LE NGGW M+DEAA HY ++DQ
Sbjct: 112 PTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQ 171
Query: 1789 TTYGHKFIKQQF--NVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRK 1616
T G +F++ F + PR+ W IDPFGHS QA L A++GFD FFGR+DYQD+ R
Sbjct: 172 MTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLF-AQMGFDGFFFGRLDYQDKWVRM 230
Query: 1615 GDKRLEVIWRASKSL-GSSSQIFAGAFPENYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQ 1439
+E +WRAS SL ++ +F G P Y PP ++V + + +D +YN +
Sbjct: 231 QKLEMEQVWRASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAK 290
Query: 1438 ERVNDFVAAAVSQANITRSNHVMWTMGTDFKYQYAESWFRNMDKLIHYVN----KDGRVN 1271
E V+ F+ A +Q R+NH + TMG+DF+Y+ A WF+N+DKLI VN K V+
Sbjct: 291 ELVDYFLNVATAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVH 350
Query: 1270 ALYSTPSIYTDAKYAETDSWPLKEEDYFPYASDINAYWTGYFTSRPGLKGYVRMLSGYYL 1091
LYSTP+ Y +W +K +D+FPYA + +WTGYF+SRP LK Y R+ +
Sbjct: 351 VLYSTPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQ 410
Query: 1090 AARQLEVLKG-RNKAGP--TTDS--LGDALGIAQHHDAVSGTSQQHVANDYAKRLAISHK 926
QLE L G GP + DS L +A+ + QHHDAVSGTS+QHVANDYA++LA
Sbjct: 411 VCNQLEALVGLAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWG 470
Query: 925 EAEVVVAESLAGMVSSKSGHESSATHFQQCPLLNISYCPPTEADLSSGKKLVVVVYNSLG 746
EV+++ +LA + K HF C LNIS CP ++ + + V+VYN LG
Sbjct: 471 PCEVLLSNALARLRGFKD-------HFTFCQQLNISICPLSQ----TAARFQVIVYNPLG 519
Query: 745 WKRSDVIRLPVVSDNIAVYDSSGKQVESQLL 653
K + ++RLPV V D +G+ V S ++
Sbjct: 520 RKVNWMVRLPVSEGVFVVKDPNGRTVPSDVV 550
>sp|O46432|MA2B1_FELCA Lysosomal alpha-mannosidase OS=Felis catus GN=MAN2B1 PE=2
SV=1
Length = 1007
Score = 422 bits (1084), Expect = 7e-117
Identities = 230/512 (44%), Positives = 310/512 (60%), Gaps = 25/512 (4%)
Frame = -2
Query: 2149 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 1970
YET V D LNVHLVAHTHDDVGWLKTVDQY+ G +N +Q A VQ +LDS++ +LL +
Sbjct: 53 YETCPMVHPDMLNVHLVAHTHDDVGWLKTVDQYFYGIHNDVQHAGVQYILDSVISSLLVE 112
Query: 1969 KNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQ 1790
R+F+YVE AFF RWW Q+ AT+ +V+ V G+LE NGGW M+DEAA HY +IDQ
Sbjct: 113 PTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIIDQ 172
Query: 1789 TTYGHKFIKQQF--NVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRK 1616
T G +F++ F + PR+ W IDPFGHS QA L A++GFD LFFGR+DYQD+ R+
Sbjct: 173 MTLGLRFLEDTFGKDGRPRVAWHIDPFGHSREQASLF-AQMGFDGLFFGRLDYQDKRVRE 231
Query: 1615 GDKRLEVIWRASKSL-GSSSQIFAGAFPENYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQ 1439
+ LE +WRAS SL ++ +F P Y PP ++ K +D +YN +
Sbjct: 232 ENLGLEQVWRASASLKPPAADLFTSVLPNIYNPPEKLCWDTLCADKPFVEDRRSPEYNAE 291
Query: 1438 ERVNDFVAAAVSQANITRSNHVMWTMGTDFKYQYAESWFRNMDKLIHYVN-----KDGRV 1274
E VN F+ A +Q R+NH + TMG+DF+Y+ A WFRN+D+LI VN RV
Sbjct: 292 ELVNYFLQLATAQGQHFRTNHTIMTMGSDFQYENANMWFRNLDRLIQLVNAQQQANGSRV 351
Query: 1273 NALYSTPSIYTDAKYAETDSWPLKEEDYFPYASDINAYWTGYFTSRPGLKGYVRMLSGYY 1094
N LYSTP+ Y +W +K++D+FPYA + +W+GYF+SRP LK Y R+ +
Sbjct: 352 NVLYSTPACYLWELNKANLTWSVKQDDFFPYADGPHQFWSGYFSSRPALKRYERLSYNFL 411
Query: 1093 LAARQLEVLKG-RNKAGP--TTDS--LGDALGIAQHHDAVSGTSQQHVANDYAKRLAISH 929
QLE L G GP + DS L A+ + QHHDAVSGTS+QHVA+DYA++LA
Sbjct: 412 QVCNQLEALAGPAANVGPYGSGDSAPLNQAMAVLQHHDAVSGTSKQHVADDYARQLAAGW 471
Query: 928 KEAEVVVAESLAGMVSSKSGHESSATHFQQCPLLNISYCPPTEADLSSGKKLVVVVYNSL 749
EV+++ +LA + SK F C LN+S CP ++ + K V +YN L
Sbjct: 472 DPCEVLLSNALARLSGSKE-------DFTYCRNLNVSVCPLSQ----TAKNFQVTIYNPL 520
Query: 748 GWKRSDVIRLPVVSDNIAVYDSSGKQVESQLL 653
G K ++RLPV V D +G V S ++
Sbjct: 521 GRKIDWMVRLPVSKHGFVVRDPNGTVVPSDVV 552
>sp|Q60HE9|MA2B1_MACFA Lysosomal alpha-mannosidase OS=Macaca fascicularis
GN=MAN2B1 PE=2 SV=1
Length = 1012
Score = 418 bits (1074), Expect = 1e-115
Identities = 228/511 (44%), Positives = 309/511 (60%), Gaps = 24/511 (4%)
Frame = -2
Query: 2149 YETGAGVVKDKLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRD 1970
YET V + LNVHLV HTHDDVGWLKTVDQY+ G N IQ A VQ +LDS++ ALL D
Sbjct: 53 YETCPTVQPNILNVHLVPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLAD 112
Query: 1969 KNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQ 1790
R+F+YVE AFF RWW Q+ A + +V+ V G+LE NGGW M+DEAA HY ++DQ
Sbjct: 113 PTRRFIYVEIAFFSRWWHQQTNAMREVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQ 172
Query: 1789 TTYGHKFIKQQF--NVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRK 1616
T G +F++ F + PR+ W IDPFGHS QA L A++GFD FFGR+DYQD+ R
Sbjct: 173 MTLGLRFLEDTFGSDGRPRVAWHIDPFGHSREQASLF-AQMGFDGFFFGRLDYQDKRVRM 231
Query: 1615 GDKRLEVIWRASKSL-GSSSQIFAGAFPENYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQ 1439
+E +WRAS SL ++ +F G P Y PP ++V + V +D +YN +
Sbjct: 232 QKLEMEQVWRASASLKPPTADLFTGVLPNGYNPPMNLCWDVLCVDQPVVEDPRSPEYNAK 291
Query: 1438 ERVNDFVAAAVSQANITRSNHVMWTMGTDFKYQYAESWFRNMDKLIHYVN----KDGRVN 1271
E V+ F+ A +Q R+NH++ TMG+DF+Y+ A WF+N+DKLI VN K V+
Sbjct: 292 ELVDYFLNVATAQGRHYRTNHIVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVH 351
Query: 1270 ALYSTPSIYTDAKYAETDSWPLKEEDYFPYASDINAYWTGYFTSRPGLKGYVRMLSGYYL 1091
LYSTP+ Y +W +K +D+FPYA + +WTGYF+SRP LK Y R+ +
Sbjct: 352 VLYSTPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQ 411
Query: 1090 AARQLEVLKG-RNKAGP--TTDS--LGDALGIAQHHDAVSGTSQQHVANDYAKRLAISHK 926
QLE L G GP + DS L A+ + QHHDAVSGTS+QHVA+DYA++LA
Sbjct: 412 VCNQLEALVGLAANVGPYGSGDSAPLNKAMAVLQHHDAVSGTSRQHVADDYARQLAAGWV 471
Query: 925 EAEVVVAESLAGMVSSKSGHESSATHFQQCPLLNISYCPPTEADLSSGKKLVVVVYNSLG 746
EV+++ +LA + K H C LNIS CP ++ + + V+VYN LG
Sbjct: 472 SCEVLLSNALARLRGFKD-------HLTFCRQLNISICPLSQ----TAARFQVIVYNPLG 520
Query: 745 WKRSDVIRLPVVSDNIAVYDSSGKQVESQLL 653
K + ++RLPV V D +G+ V S ++
Sbjct: 521 RKVNWMVRLPVSEGVFVVKDPNGRTVPSDVV 551
>sp|Q54KN4|MANF_DICDI Alpha-mannosidase F OS=Dictyostelium discoideum GN=manF
PE=3 SV=1
Length = 994
Score = 252 bits (643), Expect = 1e-065
Identities = 159/490 (32%), Positives = 252/490 (51%), Gaps = 55/490 (11%)
Frame = -2
Query: 2119 KLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRDKN--RKFVYV 1946
++ +HL+ H+H D GW T+++YY+G V++++ S+V +L + N RKFV+
Sbjct: 25 EIKLHLIPHSHCDSGWTSTMNEYYMGQ--------VKSIISSMVQSLNVESNPPRKFVWS 76
Query: 1945 EQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQTTYGHKFI 1766
E F ++WW D KN V + ++E +NGGW M+DEA +I Q + GHKFI
Sbjct: 77 EIGFLEQWWDDMPIEIKNDFIKHVKNDRIEFVNGGWVMNDEACASLESVIRQLSNGHKFI 136
Query: 1765 KQQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRKGDKRLEVIWR 1586
+++F P GWQIDPFGHS++ L A+ G+ + RI Y+ + K K +K L+ WR
Sbjct: 137 REKFGKQPESGWQIDPFGHSSLTP-TLQAQFGYKHVVLNRIHYELKKKFKEEKNLQFKWR 195
Query: 1585 AS-KSLGSSSQIFAGAFPENYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQERVNDFVAAA 1409
S + +G S I A F + Y P F D N Y + + + A
Sbjct: 196 GSPEGVGPKSDILAHVFDDFYTSPPHMSF----------DGYNFLAYGLPRLTMEMIELA 245
Query: 1408 VSQANITRSNHVMWTMGTDFKYQYAESWFRNMDKLI-----HYVNKDGRVNALYSTPSIY 1244
+++ +S HV+ MG DF ++ A F MD+L+ + N + V YST + +
Sbjct: 246 RNRSVFYKSPHVLIPMGGDFAFKNAYKSFEQMDQLVASINGQHANGESNVICQYSTLADF 305
Query: 1243 TDAKYAETDSWPLK--------EEDYFPYASDINAYWTGYFTSRPGLKGYVRMLSGYYLA 1088
+++T +W + + D+FPYA D N YWTGY+TSRP LKGY R +S +
Sbjct: 306 ----FSDTINWHNENKVSFNYYDSDFFPYADDSNTYWTGYYTSRPLLKGYERHVSSKLRS 361
Query: 1087 ARQLEVLKGRNKAGPT-TDSLGDALGIAQHHDAVSGTSQQHVANDYAKRLAISHKEAEVV 911
A L L+ K P + + I QHHDA+SGTS++HV DY RL ++A+++
Sbjct: 362 AEILSALQNDEKYYPNQLLNASKQVSILQHHDAISGTSKKHVVQDYFSRL----QKADIL 417
Query: 910 VAESLAGMVSSKSGHESSATHFQQCPLLNI--SYCPPTEADLSSGKKLVVVVYNSLGWKR 737
V+E +++S S + +++I S P D S +++N L W +
Sbjct: 418 VSEQSEKLLASALSQHSPT----KLDIIDIGGSLNFPKNNDAIS-----FILFNQLSWSK 468
Query: 736 SDVIRLPVVS 707
++I + V S
Sbjct: 469 EELISIKVQS 478
>sp|Q28949|MA2B2_PIG Epididymis-specific alpha-mannosidase OS=Sus scrofa
GN=MAN2B2 PE=1 SV=2
Length = 995
Score = 203 bits (515), Expect = 7e-051
Identities = 135/421 (32%), Positives = 210/421 (49%), Gaps = 44/421 (10%)
Frame = -2
Query: 2119 KLNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRDKNRKFVYVEQ 1940
K+ V +V H+H DVGWL TV + S+Q V +V +S+V AL R K R+F+ VEQ
Sbjct: 26 KVKVFVVPHSHMDVGWLHTVQE-------SMQ-VYVPDVYNSVVEALTRGKRRRFIAVEQ 77
Query: 1939 AFFQRWWRDQSEA-TKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQTTYGHKFIK 1763
+F+ WW + A K V+ ++ +LE + GG MHDEA H+ D I Q T GH F+
Sbjct: 78 EYFRLWWDGFASAKRKQQVRQLLAEQRLEFVLGGQVMHDEAVTHFDDQILQLTEGHGFLY 137
Query: 1762 QQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRKGDKRLEVIWRA 1583
+ F + P+ WQ+DPFG SA LL A GF+ RIDY + + + L+ +WR
Sbjct: 138 ETFGIRPQFSWQVDPFGASATTPTLL-ALAGFNGHIISRIDYDLKDTMQHTQGLQFVWRG 196
Query: 1582 SKSLGSSSQIFAGAFPENYEPPSGFYFEVND--------------DSKIVQDDVNLFDYN 1445
S+SL + +IF + GF + + + + QD +N + N
Sbjct: 197 SRSLEARQEIFTHVLDQYSYCSDGFMWNGSPRFPDRPFDMDYSAVEMPVSQDSMNHYVLN 256
Query: 1444 VQERVNDFVAAAVSQANITRSNHVMWTMGTDFKYQYAESWFRNMDKLIHYVNK---DGRV 1274
+ + VN +A R+ HV+W G D ++ A F NMD+L+ ++NK + +
Sbjct: 257 LVDNVN-------KRAAWFRTQHVLWPWGCDRQFFNASQQFANMDRLMDHINKHTPELGI 309
Query: 1273 NALYSTPSIYTDAKYAETDSWPLKE-EDYFPYASDINAYWTGYFTSRPGLKGYVRMLSGY 1097
+ Y+T + Y A +A+ SW +++ D+ PY+S WTG++TS+ GLK R S
Sbjct: 310 SMQYATLAEYFQAVFAQDVSWQVRDHRDFLPYSSAPEQTWTGFYTSQSGLKRLARRASAL 369
Query: 1096 YLAARQL---EVLKGRNK------AGPTTDSLGDALGIAQHHDAVSGTSQQHVANDYAKR 944
A L +L ++ A L A+ QHHD ++GT V + + +
Sbjct: 370 LYAGESLFTRYMLSAAHRFLDPAWALTQLQQLRWAVSEVQHHDGITGTHILAVRDMFVEH 429
Query: 943 L 941
L
Sbjct: 430 L 430
>sp|Q9Y2E5|MA2B2_HUMAN Epididymis-specific alpha-mannosidase OS=Homo sapiens
GN=MAN2B2 PE=1 SV=4
Length = 1009
Score = 132 bits (331), Expect = 1e-029
Identities = 85/244 (34%), Positives = 123/244 (50%), Gaps = 13/244 (5%)
Frame = -2
Query: 2116 LNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRDKNRKFVYVEQA 1937
+ +V H+H DVGW+ TV + A NV S+V L R + R+F+ VEQ
Sbjct: 27 IRAFVVPHSHMDVGWVYTVQE--------SMRAYAANVYTSVVEELARGQQRRFIAVEQE 78
Query: 1936 FFQRWWRD-QSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQTTYGHKFIKQ 1760
FF+ WW S+ K V+ + G+LE + GG MHDEA H D I Q T GH F+ +
Sbjct: 79 FFRLWWDGVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYE 138
Query: 1759 QFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRKGDKRLEVIWRAS 1580
F + P+ W +DPFG SA L A GF++ RIDY +A + + L+ +WR S
Sbjct: 139 TFGIRPQFSWHVDPFGASATTPTLF-ALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGS 197
Query: 1579 KSLGSSSQIFAGAFPE-NYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQERVNDFVAAAVS 1403
SL +IF + +Y PS F ++ S + V +F Q+ V ++ V+
Sbjct: 198 PSLSERQEIFTHIMDQYSYCTPSHIPF--SNRSGFYWNGVAVFPKPPQDGVYPNMSEPVT 255
Query: 1402 QANI 1391
ANI
Sbjct: 256 PANI 259
>sp|Q5RDJ3|MA2B2_PONAB Epididymis-specific alpha-mannosidase OS=Pongo abelii
GN=MAN2B2 PE=2 SV=1
Length = 1009
Score = 132 bits (331), Expect = 1e-029
Identities = 86/244 (35%), Positives = 125/244 (51%), Gaps = 13/244 (5%)
Frame = -2
Query: 2116 LNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRDKNRKFVYVEQA 1937
+ +V H+H DVGW+ TV + S+Q A NV S+V L R + R+F+ VEQ
Sbjct: 27 IRAFVVPHSHMDVGWVYTVQE-------SMQ-AYAANVYTSVVEELARGQQRRFIAVEQE 78
Query: 1936 FFQRWWRD-QSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQTTYGHKFIKQ 1760
FF+ WW S+ K+ V + G+LE + GG MHDEA H D I Q T GH F+ +
Sbjct: 79 FFRLWWGGVASDQQKHQVHQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYE 138
Query: 1759 QFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRKGDKRLEVIWRAS 1580
F + P+ W +DPFG SA L A GF++ RIDY +A + + L+ +WR S
Sbjct: 139 TFGIRPQFSWHVDPFGASATTPTLF-ALAGFNAHLSSRIDYDLKAAMQEARGLQFVWRGS 197
Query: 1579 KSLGSSSQIFAGAFPE-NYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQERVNDFVAAAVS 1403
SL +IF + +Y PS F ++ S + V +F + V ++ V+
Sbjct: 198 PSLSEQEEIFTHIMDQYSYCTPSHIPF--SNRSGFYWNGVAIFPKPPPDGVYPNMSEPVT 255
Query: 1402 QANI 1391
ANI
Sbjct: 256 PANI 259
>sp|Q54YC4|MAND_DICDI Alpha-mannosidase D OS=Dictyostelium discoideum GN=manD
PE=3 SV=1
Length = 1222
Score = 130 bits (325), Expect = 7e-029
Identities = 64/166 (38%), Positives = 93/166 (56%), Gaps = 1/166 (0%)
Frame = -2
Query: 2014 VQNVLDSLVPALLRDKNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWC 1835
VQ +L +V L DK +KF +VE FF RWW DQ+E K IV+ +++ QL I+GGW
Sbjct: 88 VQYILSGVVNELNLDKEKKFNWVEIGFFSRWWNDQNEIQKEIVRNLINNKQLSFISGGWV 147
Query: 1834 MHDEAAPHYIDMIDQTTYGHKFIKQQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLF 1655
+DEA D+I Q T GH+++K N T WQIDPFG+S+ + + +G L
Sbjct: 148 QNDEATATIDDVITQMTQGHQWLKDTLNYTVEYAWQIDPFGYSSSTPTIF-SSMGIKGLV 206
Query: 1654 FGRIDYQDRAKRKGDKRLEVIWRASKSLGSSSQIFAGAFPENYEPP 1517
R+ ++ K K +E IW+ S+SLG SQ+ +Y+ P
Sbjct: 207 INRVSNDVKSYMKSVKEMEFIWKGSESLGEQSQMLVSTLNIHYDYP 252
>sp|P27046|MA2A1_MOUSE Alpha-mannosidase 2 OS=Mus musculus GN=Man2a1 PE=1 SV=2
Length = 1150
Score = 129 bits (322), Expect = 2e-028
Identities = 62/159 (38%), Positives = 88/159 (55%), Gaps = 1/159 (0%)
Frame = -2
Query: 2011 QNVLDSLVPALLRDKNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCM 1832
Q + +++V L D +RKF++ E ++ +WW K VK + +GQLE++ GGW M
Sbjct: 192 QYIFNNMVLKLKEDSSRKFMWSEISYLAKWWDIIDIPKKEAVKSLLQNGQLEIVTGGWVM 251
Query: 1831 HDEAAPHYIDMIDQTTYGHKFIKQQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFF 1652
DEA PHY +IDQ GH+++++ V PR GW IDPFGHS AYLL GF +
Sbjct: 252 PDEATPHYFALIDQLIEGHQWLEKNLGVKPRSGWAIDPFGHSPTMAYLL-KRAGFSHMLI 310
Query: 1651 GRIDYQDRAKRKGDKRLEVIWRASKSLGSSSQIFAGAFP 1535
R+ Y + K LE WR + LGS++ I P
Sbjct: 311 QRVHYAIKKHFSLHKTLEFFWRQNWDLGSATDILCHMMP 349
>sp|Q16706|MA2A1_HUMAN Alpha-mannosidase 2 OS=Homo sapiens GN=MAN2A1 PE=1 SV=2
Length = 1144
Score = 127 bits (317), Expect = 6e-028
Identities = 61/159 (38%), Positives = 85/159 (53%), Gaps = 1/159 (0%)
Frame = -2
Query: 2011 QNVLDSLVPALLRDKNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCM 1832
Q + +++V L D RKF++ E ++ +WW K+ VK + +GQLE++ GGW M
Sbjct: 193 QYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSLIENGQLEIVTGGWVM 252
Query: 1831 HDEAAPHYIDMIDQTTYGHKFIKQQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFF 1652
DEA PHY +IDQ GH++++ V PR GW IDPFGHS AYLL G +
Sbjct: 253 PDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFGHSPTMAYLLN-RAGLSHMLI 311
Query: 1651 GRIDYQDRAKRKGDKRLEVIWRASKSLGSSSQIFAGAFP 1535
R+ Y + K LE WR + LGS + I P
Sbjct: 312 QRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMP 350
>sp|P28494|MA2A1_RAT Alpha-mannosidase 2 (Fragment) OS=Rattus norvegicus
GN=Man2a1 PE=1 SV=1
Length = 489
Score = 127 bits (317), Expect = 6e-028
Identities = 60/159 (37%), Positives = 86/159 (54%), Gaps = 1/159 (0%)
Frame = -2
Query: 2011 QNVLDSLVPALLRDKNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCM 1832
Q + +++V L D +RKF++ E ++ +WW K VK + +GQLE++ GGW M
Sbjct: 159 QYIFNNMVLKLKEDSSRKFIWSEISYLAKWWDIIDNPKKEAVKSLLQNGQLEIVTGGWVM 218
Query: 1831 HDEAAPHYIDMIDQTTYGHKFIKQQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFF 1652
DEA HY +IDQ GH+++++ V PR GW IDPFGHS YLL GF +
Sbjct: 219 ADEATTHYFALIDQLIEGHQWLEKNLGVKPRSGWAIDPFGHSPTMTYLL-KRAGFSHMLI 277
Query: 1651 GRIDYQDRAKRKGDKRLEVIWRASKSLGSSSQIFAGAFP 1535
R+ Y + K LE WR + LGS++ I P
Sbjct: 278 QRVHYSVKKHFSLQKTLEFFWRQNWDLGSTTDILCHMMP 316
>sp|O54782|MA2B2_MOUSE Epididymis-specific alpha-mannosidase OS=Mus musculus
GN=Man2b2 PE=2 SV=2
Length = 1018
Score = 126 bits (315), Expect = 1e-027
Identities = 79/243 (32%), Positives = 119/243 (48%), Gaps = 11/243 (4%)
Frame = -2
Query: 2116 LNVHLVAHTHDDVGWLKTVDQYYVGSNNSIQGACVQNVLDSLVPALLRDKNRKFVYVEQA 1937
+ +V H+H DVGW+ TV + A NV ++V L+R R+F+ VEQ
Sbjct: 27 IRAFVVPHSHMDVGWVFTVQE--------SMRAYAANVYTTVVAELVRGGQRRFIAVEQE 78
Query: 1936 FFQRWWRD-QSEATKNIVKGFVSSGQLELINGGWCMHDEAAPHYIDMIDQTTYGHKFIKQ 1760
FF+ WW SE K V+ + G+LE + GG MHDEA H D I Q T GH F+ +
Sbjct: 79 FFRLWWDGVASEQQKQQVRQLLHEGRLEFVLGGQVMHDEAVTHLDDQILQLTEGHGFLYE 138
Query: 1759 QFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGRIDYQDRAKRKGDKRLEVIWRAS 1580
F + P+ W +DPFG SA L A GF++ RIDY + + + L+ +W S
Sbjct: 139 TFGIRPQFSWHVDPFGASATTPTLF-ALAGFNAHLISRIDYDLKDAMQEAQMLQFVWHGS 197
Query: 1579 KSLGSSSQIFAGAFPENYEPPSGFYFEVNDDSKIVQDDVNLFDYNVQERVNDFVAAAVSQ 1400
SL +IF ++Y + + ++ S + V +F + V ++ V+
Sbjct: 198 PSLSGQQEIFTHVM-DHYSYCTPSHIPFSNRSGFYWNGVAVFPEPPPDGVYPNMSEPVTG 256
Query: 1399 ANI 1391
ANI
Sbjct: 257 ANI 259
>sp|Q8BRK9|MA2A2_MOUSE Alpha-mannosidase 2x OS=Mus musculus GN=Man2a2 PE=2 SV=2
Length = 1152
Score = 125 bits (312), Expect = 2e-027
Identities = 61/166 (36%), Positives = 91/166 (54%), Gaps = 2/166 (1%)
Frame = -2
Query: 2011 QNVLDSLVPALLRDKNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCM 1832
Q++L+S+V L D R+F++ E +FF +WW + S + V+ V +GQLE+ GGW M
Sbjct: 193 QHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVM 252
Query: 1831 HDEAAPHYIDMIDQTTYGHKFIKQQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFF 1652
DEA HY ++DQ GH+++++ TPR GW +DPFGHS+ YLL S+
Sbjct: 253 PDEANSHYFALVDQLIEGHQWLERNLGATPRSGWAVDPFGHSSTMPYLL-RRANLTSMLI 311
Query: 1651 GRIDYQDRAKRKGDKRLEVIWRASKSLGSSSQIFAGAFP-ENYEPP 1517
R+ Y + LE +WR SS+ IF P +Y+ P
Sbjct: 312 QRVHYAIKKHFAATHSLEFMWRQMWDSDSSTDIFCHMMPFYSYDVP 357
>sp|P49641|MA2A2_HUMAN Alpha-mannosidase 2x OS=Homo sapiens GN=MAN2A2 PE=2 SV=3
Length = 1150
Score = 122 bits (305), Expect = 1e-026
Identities = 60/166 (36%), Positives = 92/166 (55%), Gaps = 2/166 (1%)
Frame = -2
Query: 2011 QNVLDSLVPALLRDKNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCM 1832
Q++L+S+V L D R+F++ E +FF +WW + + + V+ V +GQLE+ GGW M
Sbjct: 193 QHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIATGGWVM 252
Query: 1831 HDEAAPHYIDMIDQTTYGHKFIKQQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFF 1652
DEA HY +IDQ GH+++++ TPR GW +DPFG+S+ YLL S+
Sbjct: 253 PDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYLL-RRANLTSMLI 311
Query: 1651 GRIDYQDRAKRKGDKRLEVIWRASKSLGSSSQIFAGAFP-ENYEPP 1517
R+ Y + LE +WR + SS+ IF P +Y+ P
Sbjct: 312 QRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVP 357
>sp|Q54YF7|MANB_DICDI Alpha-mannosidase B OS=Dictyostelium discoideum GN=manB
PE=3 SV=1
Length = 1035
Score = 112 bits (280), Expect = 1e-023
Identities = 51/122 (41%), Positives = 76/122 (62%), Gaps = 1/122 (0%)
Frame = -2
Query: 2005 VLDSLVPALLRDKNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHD 1826
+LD+++ L++D ++KF + E +F+ WW +QS + V+ V++GQL + GGW +D
Sbjct: 67 ILDNVINTLIKDSSKKFNWAEIYYFETWWNEQSSFLQAQVRNLVNNGQLYFVGGGWAQND 126
Query: 1825 EAAPHYIDMIDQTTYGHKFIKQQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGR 1646
E A HY +I+Q T GH+F+ +F V P IGWQIDPFG S + A L +GF R
Sbjct: 127 EGATHYQAVINQMTLGHQFLLSEFGVVPEIGWQIDPFGPSTLTATLFSL-MGFKYHVINR 185
Query: 1645 ID 1640
ID
Sbjct: 186 ID 187
>sp|Q55ER0|MANC_DICDI Alpha-mannosidase C OS=Dictyostelium discoideum GN=manC
PE=3 SV=1
Length = 1079
Score = 110 bits (274), Expect = 6e-023
Identities = 51/122 (41%), Positives = 75/122 (61%), Gaps = 1/122 (0%)
Frame = -2
Query: 2005 VLDSLVPALLRDKNRKFVYVEQAFFQRWWRDQSEATKNIVKGFVSSGQLELINGGWCMHD 1826
+L++++ L +DK++KF + E +F+RWW DQ+E +N VK +S+ Q + GGW +D
Sbjct: 64 ILNNVIETLTKDKSKKFNWAEIIYFERWWNDQNETLQNQVKQLISNKQFYFVGGGWTQND 123
Query: 1825 EAAPHYIDMIDQTTYGHKFIKQQFNVTPRIGWQIDPFGHSAVQAYLLGAEVGFDSLFFGR 1646
EA Y +I+Q T GH+F+ QF + P IGWQIDPFG S + L +GF R
Sbjct: 124 EAITDYQAVINQMTLGHQFLFNQFGIKPEIGWQIDPFGPSTLTPTLFKL-MGFKYHVINR 182
Query: 1645 ID 1640
ID
Sbjct: 183 ID 184
Database: Uniprot/SwissProt
Posted date: Thu Sep 27 17:53:50 2012
Number of letters in database: 190,795,139
Number of sequences in database: 537,505
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 181,605,474,615
Number of Sequences: 537505
Number of Extensions: 181605474615
Number of Successful Extensions: 1062874541
Number of sequences better than 0.0: 0
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