SwissProt blast output of UN92921
BLASTX 7.6.2
Query= UN92921 /QuerySize=755
(754 letters)
Database: Uniprot/SwissProt;
537,505 sequences; 190,795,139 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q3SZH7|LKHA4_BOVIN Leukotriene A-4 hydrolase OS=Bos taurus GN... 111 5e-024
sp|P09960|LKHA4_HUMAN Leukotriene A-4 hydrolase OS=Homo sapiens ... 109 2e-023
sp|A6SAG8|LKHA4_BOTFB Leukotriene A-4 hydrolase homolog OS=Botry... 107 1e-022
sp|P19602|LKHA4_CAVPO Leukotriene A-4 hydrolase OS=Cavia porcell... 106 2e-022
sp|Q6S9C8|LKHA4_CHILA Leukotriene A-4 hydrolase OS=Chinchilla la... 106 2e-022
sp|P24527|LKHA4_MOUSE Leukotriene A-4 hydrolase OS=Mus musculus ... 104 7e-022
sp|P52922|LKHA4_DICDI Leukotriene A-4 hydrolase homolog OS=Dicty... 96 2e-019
sp|A2QKF8|LKHA4_ASPNC Leukotriene A-4 hydrolase homolog OS=Asper... 89 4e-017
sp|A6RCT2|LKHA4_AJECN Leukotriene A-4 hydrolase homolog OS=Ajell... 87 1e-016
sp|Q2GY21|LKHA4_CHAGB Leukotriene A-4 hydrolase homolog OS=Chaet... 86 3e-016
sp|Q5B0W8|LKHA4_EMENI Leukotriene A-4 hydrolase homolog OS=Emeri... 85 4e-016
sp|A1DG68|LKHA4_NEOFI Leukotriene A-4 hydrolase homolog OS=Neosa... 85 5e-016
sp|A4QUC1|LKHA4_MAGO7 Leukotriene A-4 hydrolase homolog OS=Magna... 82 4e-015
sp|Q0U653|LKHA4_PHANO Leukotriene A-4 hydrolase homolog OS=Phaeo... 78 7e-014
sp|Q1DVD1|LKHA4_COCIM Leukotriene A-4 hydrolase homolog OS=Cocci... 74 1e-012
sp|A7EJL9|LKHA4_SCLS1 Leukotriene A-4 hydrolase homolog OS=Scler... 74 1e-012
sp|A1CSI2|LKHA4_ASPCL Leukotriene A-4 hydrolase homolog OS=Asper... 74 1e-012
sp|Q0CFY9|LKHA4_ASPTN Leukotriene A-4 hydrolase homolog OS=Asper... 72 3e-012
sp|Q6C3E5|LKHA4_YARLI Leukotriene A-4 hydrolase homolog OS=Yarro... 72 5e-012
sp|Q4X265|LKHA4_ASPFU Leukotriene A-4 hydrolase homolog OS=Neosa... 70 1e-011
>sp|Q3SZH7|LKHA4_BOVIN Leukotriene A-4 hydrolase OS=Bos taurus GN=LTA4H PE=2
SV=3
Length = 611
Score = 111 bits (277), Expect = 5e-024
Identities = 71/208 (34%), Positives = 107/208 (51%), Gaps = 24/208 (11%)
Frame = -2
Query: 606 TTHISLNLYFNFPSSKIHSSALLTLKNHYTG--DLILDTRNLSISAVFDPLNNTQIPFCL 433
T H+ L +F + +A LT+++ LILDT++L+I V +N ++ + L
Sbjct: 19 TKHLHLRCSIDFTRRVLSGTAALTIQSQEDNLRSLILDTKDLTIEKVV--INGQEVKYTL 76
Query: 432 SSEVDPIKGQALTVSLTNCNC------FLVVYETSACSSALQWLNPLQTFNKKFGFVYTQ 271
E KG + +SL C + +ETS SSALQWL P QT K+ ++++Q
Sbjct: 77 -GERQSYKGSPIEISLPIALCKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQ 135
Query: 270 CQSIHARSIFPCQDTPSLRVKYSARLNIPRELGCVMSAKHVERRGPMRGENGMCCDEGLW 91
CQ+IH R+I PCQDTPS+++ YSA +++P+EL +MSA N
Sbjct: 136 CQAIHCRAILPCQDTPSVKLTYSAEVSVPKELVALMSAIRDGEAPDPEDPN--------- 186
Query: 90 CGDGRVVEEFVMEQPIPTYLFAFAVGEI 7
R + F + PIP YL A VG +
Sbjct: 187 ----RKIYRFSQKVPIPCYLIALVVGAL 210
>sp|P09960|LKHA4_HUMAN Leukotriene A-4 hydrolase OS=Homo sapiens GN=LTA4H PE=1
SV=2
Length = 611
Score = 109 bits (272), Expect = 2e-023
Identities = 71/209 (33%), Positives = 114/209 (54%), Gaps = 26/209 (12%)
Frame = -2
Query: 606 TTHISLNLYFNFPSSKIHSSALLTLKNHYTG--DLILDTRNLSISAVFDPLNNTQIPFCL 433
T H+ L +F + +A LT+++ L+LDT++L+I V +N ++ + L
Sbjct: 19 TKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVV--INGQEVKYAL 76
Query: 432 SSEVDPIKGQALTVSL---TNCNCFLVV---YETSACSSALQWLNPLQTFNKKFGFVYTQ 271
E KG + +SL + N +V+ +ETS SSALQWL P QT K+ ++++Q
Sbjct: 77 -GERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQ 135
Query: 270 CQSIHARSIFPCQDTPSLRVKYSARLNIPRELGCVMSA-KHVERRGPMRGENGMCCDEGL 94
CQ+IH R+I PCQDTPS+++ Y+A +++P+EL +MSA + E P
Sbjct: 136 CQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPE------------ 183
Query: 93 WCGDGRVVEEFVMEQPIPTYLFAFAVGEI 7
R + +F+ + PIP YL A VG +
Sbjct: 184 --DPSRKIYKFIQKVPIPCYLIALVVGAL 210
>sp|A6SAG8|LKHA4_BOTFB Leukotriene A-4 hydrolase homolog OS=Botryotinia
fuckeliana (strain B05.10) GN=BC1G_09514 PE=1 SV=2
Length = 616
Score = 107 bits (266), Expect = 1e-022
Identities = 72/230 (31%), Positives = 116/230 (50%), Gaps = 22/230 (9%)
Frame = -2
Query: 669 TLISTMAPIDPHSFTDSSHPLTTHISLNLYFNFPSSKIHSSALLTLK---NHYTGDLILD 499
T+ + P DP++ ++ ++ T H +L +F ++H + L L+ + + ++ILD
Sbjct: 3 TVSTINMPRDPNTLSNYNNWRTKHTIADLAIDFTKQRVHGTVTLQLESITDKESEEIILD 62
Query: 498 TRNLSISAVFDPLNNTQIPFCLSSEVDPIKGQALTVSLT------NCNCFLVVYETSACS 337
T + + +V N T + L ++P G L+V + + T+
Sbjct: 63 TSFVDVQSVAVDGNKTG-EWTLEKRIEPF-GTPLSVKIPGGAAKGTVIALAITLSTTDKC 120
Query: 336 SALQWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIPRELGCVMSA 157
+ALQWL P QT NKKF ++++QCQ+IH RSIFPCQDTP ++ Y R+ P L + S
Sbjct: 121 TALQWLTPAQTSNKKFPYMFSQCQAIHNRSIFPCQDTPDVKSTYDFRIRSP--LPVLASG 178
Query: 156 KHVERRGPMRGENGMCCDEGLWCGDGRVVEEFVMEQPIPTYLFAFAVGEI 7
+ GENG G ++ F E P+P+YLFA A G+I
Sbjct: 179 LPRGAGSFVHGENG---------ESGTLLYSFYQEIPMPSYLFALASGDI 219
>sp|P19602|LKHA4_CAVPO Leukotriene A-4 hydrolase OS=Cavia porcellus GN=LTA4H
PE=1 SV=3
Length = 611
Score = 106 bits (264), Expect = 2e-022
Identities = 71/209 (33%), Positives = 111/209 (53%), Gaps = 26/209 (12%)
Frame = -2
Query: 606 TTHISLNLYFNFPSSKIHSSALLTLKNHYTG--DLILDTRNLSISAVFDPLNNTQIPFCL 433
T H+ L +F + A LT+++ LILDT++L+I V +N ++ + L
Sbjct: 19 TKHLHLRCSVDFTRRALTGVAALTIQSQEDNLRSLILDTKDLTIEKVV--INGQEVKYAL 76
Query: 432 SSEVDPIKGQALTVSL---TNCNCFLVV---YETSACSSALQWLNPLQTFNKKFGFVYTQ 271
E KG + +SL + N +V+ +ETS SSALQWL P QT K+ ++++Q
Sbjct: 77 -GEKQSYKGSPMEISLPIALSKNQEVVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQ 135
Query: 270 CQSIHARSIFPCQDTPSLRVKYSARLNIPRELGCVMSA-KHVERRGPMRGENGMCCDEGL 94
CQ+IH R+ PCQDTPS+++ Y+A +++P+EL +MSA + E P
Sbjct: 136 CQAIHCRAFLPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDP------------- 182
Query: 93 WCGDGRVVEEFVMEQPIPTYLFAFAVGEI 7
R + +F + PIP YL A VG +
Sbjct: 183 -ADPSRKIYKFSQKVPIPCYLIALVVGAL 210
>sp|Q6S9C8|LKHA4_CHILA Leukotriene A-4 hydrolase OS=Chinchilla lanigera GN=LTA4H
PE=2 SV=3
Length = 611
Score = 106 bits (264), Expect = 2e-022
Identities = 71/209 (33%), Positives = 112/209 (53%), Gaps = 26/209 (12%)
Frame = -2
Query: 606 TTHISLNLYFNFPSSKIHSSALLTLKNHYTG--DLILDTRNLSISAVFDPLNNTQIPFCL 433
T H+ L +F S + A LT+++ L+LDT+ L+I V +N ++ + L
Sbjct: 19 TKHLHLRCSVDFSSRALTGIAALTIQSQEDNLRSLVLDTKALTIEKVV--INGQEVKYAL 76
Query: 432 SSEVDPIKGQALTVSL---TNCNCFLVV---YETSACSSALQWLNPLQTFNKKFGFVYTQ 271
E KG + +SL + N +V+ +ETS SSALQWL P QT K+ ++++Q
Sbjct: 77 -GERQSYKGSPMEISLPIALSKNQEVVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQ 135
Query: 270 CQSIHARSIFPCQDTPSLRVKYSARLNIPRELGCVMSA-KHVERRGPMRGENGMCCDEGL 94
CQ+IH R++ PCQDTPS+++ Y+A +++P+EL +MSA + E P
Sbjct: 136 CQAIHCRAVLPCQDTPSVKLTYTAEVSVPKELVALMSAVRDGETPDPE------------ 183
Query: 93 WCGDGRVVEEFVMEQPIPTYLFAFAVGEI 7
R + +F + PIP YL A VG +
Sbjct: 184 --DPSRKIYKFNQKVPIPCYLIALVVGAL 210
>sp|P24527|LKHA4_MOUSE Leukotriene A-4 hydrolase OS=Mus musculus GN=Lta4h PE=1
SV=4
Length = 611
Score = 104 bits (259), Expect = 7e-022
Identities = 71/209 (33%), Positives = 110/209 (52%), Gaps = 26/209 (12%)
Frame = -2
Query: 606 TTHISLNLYFNFPSSKIHSSALLTLKNHYTG--DLILDTRNLSISAVFDPLNNTQIPFCL 433
T H+ L +F + +A LT+++ L LDT++L+I V +N ++ + L
Sbjct: 19 TQHLHLRCSVDFARRTLTGTAALTVQSQEENLRSLTLDTKDLTIEKVV--INGQEVKYTL 76
Query: 432 SSEVDPIKGQALTVSL---TNCNCFLVV---YETSACSSALQWLNPLQTFNKKFGFVYTQ 271
E KG + +SL + N +V+ +ETS SSALQWL P QT K+ ++++Q
Sbjct: 77 -GESQGYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKQHPYLFSQ 135
Query: 270 CQSIHARSIFPCQDTPSLRVKYSARLNIPRELGCVMSA-KHVERRGPMRGENGMCCDEGL 94
CQ+IH R+I PCQDTPS+++ Y+A +++P+EL +MSA + E P
Sbjct: 136 CQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPE------------ 183
Query: 93 WCGDGRVVEEFVMEQPIPTYLFAFAVGEI 7
R + F PIP YL A VG +
Sbjct: 184 --DPSRKIYRFNQRVPIPCYLIALVVGAL 210
>sp|P52922|LKHA4_DICDI Leukotriene A-4 hydrolase homolog OS=Dictyostelium
discoideum GN=lkhA PE=2 SV=2
Length = 606
Score = 96 bits (237), Expect = 2e-019
Identities = 64/172 (37%), Positives = 92/172 (53%), Gaps = 11/172 (6%)
Frame = -2
Query: 645 IDPHSFTDSSHPLTTHISLNLYFNFPSSKI--HSSALLTLKNHYTGDLILDTRNLSISAV 472
+DP S ++ T ++L L NF S++ + + T LILDT L IS
Sbjct: 1 MDPSSLSNPQECKVTSLNLVLSVNFEKSQLQGYVEVASQIVKEGTESLILDTNQLEISHC 60
Query: 471 FDPLNNTQIPFCLSSEVDPIKGQALTVSLTNC-------NCFLVVYETSACSSALQWLNP 313
D +N I F LS E + G+AL +S+ V Y T+ S+ALQWL
Sbjct: 61 NDVTSN-PINFKLSEE-HKVFGKALIISIPEGLRSVGKEFIVRVYYNTTVDSNALQWLTK 118
Query: 312 LQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIPRELGCVMSA 157
QT K ++++QCQ+IHARS+ PCQD+PS +VKY A + +P+ L +MSA
Sbjct: 119 DQTAGKLHPYLFSQCQAIHARSLVPCQDSPSNKVKYQAEITVPKPLTALMSA 170
>sp|A2QKF8|LKHA4_ASPNC Leukotriene A-4 hydrolase homolog OS=Aspergillus niger
(strain CBS 513.88 / FGSC A1513) GN=An05g00070 PE=3 SV=2
Length = 618
Score = 89 bits (218), Expect = 4e-017
Identities = 66/198 (33%), Positives = 103/198 (52%), Gaps = 20/198 (10%)
Frame = -2
Query: 663 ISTMAPIDPHSFTDSSHPLTTHISLNLYFNFPSSKIHSSALLTLKNHYTG---DLILDTR 493
IS P DP++ ++ ++ + THI+ N F K+ + + LK+ G ++ILD+
Sbjct: 3 ISIHPPRDPNTLSNYNNWICTHITANFDILFDQKKLVGNVIHKLKSTTNGESQEIILDSN 62
Query: 492 NLSISAVFDPLNNTQIPFCLSSEVDPIKGQALTVSL---TNCNCFL---VVYETSACSSA 331
+++I V ++ + L ++P G AL + L N N + + +T+ +A
Sbjct: 63 HVAIGDV--KIDGRPSEWELLPPLEPY-GSALKIKLDQGVNLNETIDVEISVQTTEKCTA 119
Query: 330 LQWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIPRELGCVMSAKH 151
LQWL P QT NKK ++++QCQ+IHARSIFPCQDTP VK + NI L + S
Sbjct: 120 LQWLTPAQTSNKKHPYMFSQCQAIHARSIFPCQDTPD--VKSTIDFNISSPLPVIASGL- 176
Query: 150 VERRGPMRGENGMCCDEG 97
P+R G EG
Sbjct: 177 -----PVRDALGASKSEG 189
>sp|A6RCT2|LKHA4_AJECN Leukotriene A-4 hydrolase homolog OS=Ajellomyces
capsulata (strain NAm1 / WU24) GN=HCAG_07440 PE=3 SV=2
Length = 623
Score = 87 bits (214), Expect = 1e-016
Identities = 58/168 (34%), Positives = 90/168 (53%), Gaps = 12/168 (7%)
Frame = -2
Query: 660 STMAPIDPHSFTDSSHPLTTHISLNLYFNFPSSKIHSSA---LLTLKNHYTGDLILDTRN 490
ST P DP++ ++ + TTH ++N F K+ + L++L N ++ILD+
Sbjct: 10 STNPPRDPNTLSNYNAFRTTHTTVNFDILFEKQKLTGNVMHKLISLTNLEAREVILDSSF 69
Query: 489 LSISAVFDPLNNTQIPFCLSSEVDPIKGQALT------VSLTNCNCFLVVYETSACSSAL 328
L+I V ++ Q F L +P G AL V+L+ + ET+ +AL
Sbjct: 70 LNIHDV--KVDGKQSKFELLPRQEPY-GSALKIPLAEGVALSKTLDIDITVETTEKCTAL 126
Query: 327 QWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIP 184
QWL P QT +K +++TQCQ+IHARSIFPCQDTP ++ ++ P
Sbjct: 127 QWLTPAQTSTQKHPYMFTQCQAIHARSIFPCQDTPDVKAVIDFNISSP 174
>sp|Q2GY21|LKHA4_CHAGB Leukotriene A-4 hydrolase homolog OS=Chaetomium globosum
(strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)
GN=CHGG_07133 PE=3 SV=1
Length = 611
Score = 86 bits (210), Expect = 3e-016
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 15/168 (8%)
Frame = -2
Query: 654 MAPI-DPHSFTDSSHPLTTHISLNLYFNFPSSKIHSSALLTLKNH---YTGDLILDTRNL 487
MAP+ DP++ ++ + T H + + +F + + S +L L++ + ++ILD+ +
Sbjct: 1 MAPVRDPNTLSNYNEWRTKHTTADFKVDFTAKCLRGSVVLELESQTDKASKEIILDSSYV 60
Query: 486 SISAVFDPLNNTQIPFCLSSEVDPIKGQALTVSLTN-------CNCFLVVYETSACSSAL 328
+SA+ LN+T + + P G + V++ N + + T C +AL
Sbjct: 61 DVSAI--TLNSTPSQWEVRDRTGP-SGSPVRVAVPNGAGKGEVVKLEIELATTDKC-TAL 116
Query: 327 QWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIP 184
QWL P QT NKK F+++QCQ+IHARSIFPCQDTP ++ Y + P
Sbjct: 117 QWLTPAQTSNKKAPFMFSQCQAIHARSIFPCQDTPDVKSTYDFIIRSP 164
>sp|Q5B0W8|LKHA4_EMENI Leukotriene A-4 hydrolase homolog OS=Emericella nidulans
(strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=AN5812
PE=3 SV=2
Length = 618
Score = 85 bits (209), Expect = 4e-016
Identities = 56/174 (32%), Positives = 91/174 (52%), Gaps = 18/174 (10%)
Frame = -2
Query: 666 LISTMAPI-DPHSFTDSSHPLTTHISLNLYFNFPSSKIHSSA---LLTLKNHYTGDLILD 499
+ + M P+ DP++ ++ ++ L TH + N F K+ + L ++ N T ++ILD
Sbjct: 1 MATLMNPVRDPNTLSNYNNWLCTHTTANFEIFFEEKKLVGNVVHKLRSITNAETDEIILD 60
Query: 498 TRNLSISAVFDPLNNTQIPFCLSSEVDPI--KGQALTVSLTN-------CNCFLVVYETS 346
+ ++ I V +P + P+ G AL + L N + + V T
Sbjct: 61 SHHVDIRNV----QVAGLPVKAWELLPPLGPYGTALKIKLENPVGLNEIIDVDIAVQTTK 116
Query: 345 ACSSALQWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIP 184
C +ALQWL P QT NKK ++++QCQ+IHARSIFPCQDTP ++ + + P
Sbjct: 117 EC-TALQWLTPAQTSNKKHPYMFSQCQAIHARSIFPCQDTPDVKCTFDFNITSP 169
>sp|A1DG68|LKHA4_NEOFI Leukotriene A-4 hydrolase homolog OS=Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) GN=NFIA_083260
PE=3 SV=1
Length = 617
Score = 85 bits (208), Expect = 5e-016
Identities = 62/186 (33%), Positives = 97/186 (52%), Gaps = 20/186 (10%)
Frame = -2
Query: 648 PIDPHSFTDSSHPLTTHISLNLYFNFPSSKIHSSALLTLKNHYTGD---LILDTRNLSIS 478
P DP++ ++ ++ ++THI+ N F K+ S + ++ G+ +ILDT +L I
Sbjct: 8 PRDPNTLSNYNNWVSTHITANFDILFDQRKLAGSVIHQFRSTTHGESNHIILDTNHLDIG 67
Query: 477 AVFDPLNNTQIPFCLSSEVDPIKGQALTVSL---TNCNCFLVV---YETSACSSALQWLN 316
+V +N + ++P G L + L N + V +T+ +ALQWL
Sbjct: 68 SV--KVNGQPSEWEYLPRLEPY-GTPLKIKLDQGVKLNEMIEVDISVKTTEKCTALQWLT 124
Query: 315 PLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIPRELGCVMSAKHVERRG 136
P QT NKK ++++QCQ+IHARSIFPCQDTP VK + NI L + S
Sbjct: 125 PAQTSNKKHPYMFSQCQAIHARSIFPCQDTPD--VKCTLDFNITSPLPVIASGL------ 176
Query: 135 PMRGEN 118
P+RG +
Sbjct: 177 PVRGSS 182
>sp|A4QUC1|LKHA4_MAGO7 Leukotriene A-4 hydrolase homolog OS=Magnaporthe oryzae
(strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=MGG_09481 PE=3 SV=2
Length = 613
Score = 82 bits (201), Expect = 4e-015
Identities = 53/167 (31%), Positives = 87/167 (52%), Gaps = 14/167 (8%)
Frame = -2
Query: 654 MAPIDPHSFTDSSHPLTTHISLNLYFNFPSSKIHSSALLTLKNH---YTGDLILDTRNLS 484
MA DP + ++ T H + NL +F + S +L L++ + +++LD+ +S
Sbjct: 1 MAARDPSTASNYDAWKTKHTTANLRIDFDDKCLRGSVVLELESRTAKESKEIVLDSSYVS 60
Query: 483 ISAVFDPLNNTQIPFCLSSEVDPIKGQALTVSLTN-------CNCFLVVYETSACSSALQ 325
+ ++ LN+ Q + + P+ G L +S+ + V T C +ALQ
Sbjct: 61 VESI--KLNDVQTKWEIKERNGPM-GSPLHISVPEGADSGEVVRLEMAVKTTPQC-TALQ 116
Query: 324 WLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIP 184
WL P QT NKK F+++Q Q+ HARS+FPCQDTP ++ YS + P
Sbjct: 117 WLTPAQTSNKKAPFMFSQAQACHARSLFPCQDTPDVKSTYSFNITSP 163
>sp|Q0U653|LKHA4_PHANO Leukotriene A-4 hydrolase homolog OS=Phaeosphaeria
nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) GN=SNOG_12761 PE=3
SV=2
Length = 623
Score = 78 bits (190), Expect = 7e-014
Identities = 43/117 (36%), Positives = 65/117 (55%), Gaps = 11/117 (9%)
Frame = -2
Query: 513 DLILDTRNLSISAVFDPLNNTQIPFCLSSEVDPIKGQALTVSL-------TNCNCFLVVY 355
D++LD+ L +SA+ ++ F + ++P G LT+ L L V
Sbjct: 53 DVVLDSSFLDVSAI--KVDRQSAEFSIGERIEPY-GSPLTIKLPAAVPKGKTVEIELTVA 109
Query: 354 ETSACSSALQWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIP 184
T C +ALQW+ P QT NKK ++++QCQ+ HARS+FPCQDTP ++ +S L P
Sbjct: 110 TTEKC-TALQWMEPAQTSNKKHPYMFSQCQANHARSVFPCQDTPDVKSTFSFALRSP 165
>sp|Q1DVD1|LKHA4_COCIM Leukotriene A-4 hydrolase homolog OS=Coccidioides immitis
(strain RS) GN=CIMG_05732 PE=3 SV=2
Length = 621
Score = 74 bits (180), Expect = 1e-012
Identities = 46/127 (36%), Positives = 69/127 (54%), Gaps = 11/127 (8%)
Frame = -2
Query: 543 LLTLKNHYTGDLILDTRNLSISAVFDPLNNTQIPFCLSSEVDPIKGQALTVSLTNC---- 376
L +L N + ++ILD+ L + +V +N + L +P G L +SL
Sbjct: 46 LKSLTNAESKEVILDSSYLEVKSV--KVNGEAAEWQLLPRFEPY-GSPLKISLEQAIPLD 102
Query: 375 ---NCFLVVYETSACSSALQWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKY 205
+ V T C +ALQWLNP QT N K ++++QCQ+IHAR+IFPCQDTP ++ +
Sbjct: 103 ELIEVDISVNTTEKC-TALQWLNPEQTSNGKHPYMFSQCQAIHARAIFPCQDTPDVKATF 161
Query: 204 SARLNIP 184
L+ P
Sbjct: 162 DFNLSSP 168
>sp|A7EJL9|LKHA4_SCLS1 Leukotriene A-4 hydrolase homolog OS=Sclerotinia
sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) GN=SS1G_05513 PE=3 SV=1
Length = 608
Score = 74 bits (180), Expect = 1e-012
Identities = 38/84 (45%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Frame = -2
Query: 366 LVVYETSACSSALQWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNI 187
+ + T C +ALQWL P QT NKKF ++++QCQ+IH RSIFPCQDTP ++ Y R+
Sbjct: 104 ITISTTDKC-TALQWLTPAQTSNKKFPYMFSQCQAIHNRSIFPCQDTPDVKSTYDFRIRS 162
Query: 186 PRELGCVMSAKHVERRGPMRGENG 115
P L + S + GENG
Sbjct: 163 P--LPVLASGLPRGAASFVHGENG 184
>sp|A1CSI2|LKHA4_ASPCL Leukotriene A-4 hydrolase homolog OS=Aspergillus clavatus
(strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
GN=ACLA_079530 PE=3 SV=1
Length = 618
Score = 74 bits (179), Expect = 1e-012
Identities = 50/132 (37%), Positives = 68/132 (51%), Gaps = 13/132 (9%)
Frame = -2
Query: 513 DLILDTRNLSISAVFDPLNNTQIPFCLSSEVDPIKGQALTVSLTNC-------NCFLVVY 355
D+ILDT +L I V +N + ++P G L + L + V
Sbjct: 56 DIILDTNHLDIGGV--KVNGQPSSWEFLPRLEPY-GTPLKIKLDQAVELDETIEVDISVT 112
Query: 354 ETSACSSALQWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIPREL 175
T C +ALQWL P QT NKK ++++QCQ+IHARSIFPCQDTP VK + NI L
Sbjct: 113 TTEKC-TALQWLTPAQTSNKKHPYMFSQCQAIHARSIFPCQDTPD--VKCTLDFNITSPL 169
Query: 174 GCVMSAKHVERR 139
+ S V ++
Sbjct: 170 PVIASGLPVRKQ 181
>sp|Q0CFY9|LKHA4_ASPTN Leukotriene A-4 hydrolase homolog OS=Aspergillus terreus
(strain NIH 2624 / FGSC A1156) GN=ATEG_06861 PE=3 SV=2
Length = 617
Score = 72 bits (176), Expect = 3e-012
Identities = 50/135 (37%), Positives = 73/135 (54%), Gaps = 13/135 (9%)
Frame = -2
Query: 543 LLTLKNHYTGDLILDTRNLSISAVFDPLNNTQIPFCLSSEVDPIKGQALTVSLTN----- 379
L ++ N + D++LDT ++ ++ V ++ + L V P G AL + L
Sbjct: 46 LKSITNAESTDIVLDTSHVDVTDV--KVDGKPSVWELLPPVKPY-GTALKIKLDQGVKMD 102
Query: 378 --CNCFLVVYETSACSSALQWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKY 205
+ + V T C +ALQWL P QT NKK ++++QCQ+IHARSIFPCQDTP VK
Sbjct: 103 EIVHVDISVKTTEKC-TALQWLTPAQTSNKKHPYMFSQCQAIHARSIFPCQDTPD--VKS 159
Query: 204 SARLNIPRELGCVMS 160
+ NI L + S
Sbjct: 160 TIDFNITSPLPVIAS 174
>sp|Q6C3E5|LKHA4_YARLI Leukotriene A-4 hydrolase homolog OS=Yarrowia lipolytica
(strain CLIB 122 / E 150) GN=YALI0F00396g PE=3 SV=1
Length = 647
Score = 72 bits (174), Expect = 5e-012
Identities = 52/156 (33%), Positives = 82/156 (52%), Gaps = 10/156 (6%)
Frame = -2
Query: 642 DPHSFTDSSHPLTTHISLNLYFNFPSSKIHSSAL--LTLKNHYTGDLILDTRNLSISAVF 469
DP + ++ H T+ ++ L ++ K+ S LT++N +L+LDT L I V
Sbjct: 44 DPSTLSNYEHFKPTNTTVCLKVDWTDQKLAGSVTYDLTVENS-PKNLVLDTSYLDIQEV- 101
Query: 468 DPLNNTQIPFCLSSEVDPIKGQALTVSL-TNCNCFL---VVYETSACSSALQWLNPLQTF 301
+N + F + E I G LT++L N L + Y T+ +ALQWL P QT
Sbjct: 102 -QVNGHKADFSI-GERHNIFGSPLTITLPPNSGDKLQVKIAYSTTPSCTALQWLTPEQTA 159
Query: 300 NKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARL 193
KK + ++QCQ+IHARS+ P DTPS++ + +
Sbjct: 160 GKKAPYFFSQCQAIHARSVMPAFDTPSVKSTFDIEI 195
>sp|Q4X265|LKHA4_ASPFU Leukotriene A-4 hydrolase homolog OS=Neosartorya fumigata
(strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
GN=AFUA_2G07520 PE=3 SV=1
Length = 614
Score = 70 bits (171), Expect = 1e-011
Identities = 51/138 (36%), Positives = 70/138 (50%), Gaps = 19/138 (13%)
Frame = -2
Query: 510 LILDTRNLSISAVFDPLNNTQIPFCLSSEVDPIKGQALTVSL-------TNCNCFLVVYE 352
+ILDT +L I +V +N + ++P G L + L + V
Sbjct: 57 IILDTNHLDIGSV--KVNGQPSEWEYLPRLEPY-GTPLKIKLDQGVKLNETIEVDISVQT 113
Query: 351 TSACSSALQWLNPLQTFNKKFGFVYTQCQSIHARSIFPCQDTPSLRVKYSARLNIPRELG 172
T C +ALQWL P QT NKK ++++QCQ+IHARSIFPCQDTP VK + NI L
Sbjct: 114 TEKC-TALQWLTPAQTSNKKHPYMFSQCQAIHARSIFPCQDTPD--VKCTLDFNITSPLP 170
Query: 171 CVMSAKHVERRGPMRGEN 118
+ S P+RG +
Sbjct: 171 VIASGL------PVRGSS 182
Database: Uniprot/SwissProt
Posted date: Thu Sep 27 17:53:50 2012
Number of letters in database: 190,795,139
Number of sequences in database: 537,505
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 172,875,407,866
Number of Sequences: 537505
Number of Extensions: 172875407866
Number of Successful Extensions: 1014195352
Number of sequences better than 0.0: 0
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