SwissProt blast output of UN91810
BLASTX 7.6.2
Query= UN91810 /QuerySize=1807
(1806 letters)
Database: Uniprot/SwissProt;
537,505 sequences; 190,795,139 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P14868|SYDC_HUMAN Aspartate--tRNA ligase, cytoplasmic OS=Homo... 474 1e-132
sp|P15178|SYDC_RAT Aspartate--tRNA ligase, cytoplasmic OS=Rattus... 473 2e-132
sp|Q922B2|SYDC_MOUSE Aspartate--tRNA ligase, cytoplasmic OS=Mus ... 473 2e-132
sp|Q5R9I5|SYDC_PONAB Aspartate--tRNA ligase, cytoplasmic OS=Pong... 471 9e-132
sp|Q3SYZ4|SYDC_BOVIN Aspartate--tRNA ligase, cytoplasmic OS=Bos ... 470 3e-131
sp|P04802|SYDC_YEAST Aspartate--tRNA ligase, cytoplasmic OS=Sacc... 430 2e-119
sp|Q03577|SYDC_CAEEL Aspartate--tRNA ligase, cytoplasmic OS=Caen... 427 2e-118
sp|Q75JQ1|SYDC1_DICDI Aspartate--tRNA ligase, cytoplasmic 1 OS=D... 339 4e-092
sp|Q8SRQ8|SYDC_ENCCU Probable aspartate--tRNA ligase, cytoplasmi... 305 9e-082
sp|B7XHQ4|SYDC_ENTBH Probable aspartate--tRNA ligase, cytoplasmi... 290 2e-077
sp|O74407|SYDC_SCHPO Aspartate--tRNA ligase, cytoplasmic OS=Schi... 271 1e-071
sp|Q9V036|SYD_PYRAB Aspartate--tRNA ligase OS=Pyrococcus abyssi ... 258 9e-068
sp|O58776|SYD_PYRHO Aspartate--tRNA ligase OS=Pyrococcus horikos... 248 1e-064
sp|Q9Y9U7|SYD_AERPE Aspartate--tRNA ligase OS=Aeropyrum pernix (... 247 3e-064
sp|Q8TQ68|SYD_METAC Aspartate--tRNA ligase OS=Methanosarcina ace... 246 6e-064
sp|Q8U2G6|SYD_PYRFU Aspartate--tRNA ligase OS=Pyrococcus furiosu... 243 3e-063
sp|Q466Y5|SYD_METBF Aspartate--tRNA ligase OS=Methanosarcina bar... 243 5e-063
sp|Q52428|SYD_PYRKO Aspartate--tRNA ligase OS=Pyrococcus kodakar... 237 3e-061
sp|Q12XU7|SYD_METBU Aspartate--tRNA ligase OS=Methanococcoides b... 235 9e-061
sp|Q8TXG4|SYD_METKA Aspartate--tRNA ligase OS=Methanopyrus kandl... 160 3e-038
>sp|P14868|SYDC_HUMAN Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens
GN=DARS PE=1 SV=2
Length = 501
Score = 474 bits (1218), Expect = 1e-132
Identities = 247/478 (51%), Positives = 322/478 (67%), Gaps = 8/478 (1%)
Frame = -3
Query: 1732 ITDLQSPQTPPTRLFNTVKSLGKEMEGESVWVRGRVFAIRPVAKKMCFFTVREMGSSVQC 1553
I+ + Q P R+ V+ L + E VWVR RV R K+ CF +R+ +VQ
Sbjct: 31 ISSMIQSQEKPDRVLVRVRDLTIQKADEVVWVRARVHTSRAKGKQ-CFLVLRQQQFNVQA 89
Query: 1552 VLSVAEGLVSAQMVKFAVGISKESFVDVEGVVSVPKAPITGASQQ-VEIQVRKIYCVNRA 1376
+++V + S QMVKFA I+KES VDVEGVV I +QQ VE+ V+KIY ++ A
Sbjct: 90 LVAVGDH-ASKQMVKFAANINKESIVDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLA 148
Query: 1375 APVLPISIEDASRSEAEIESALELGEQLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVL 1196
P LP+ ++DA R EAE E E VNQDTRL+ RV+D+RT +QA+F L+S +
Sbjct: 149 EPRLPLQLDDAVRPEAEGEE-----EGRATVNQDTRLDNRVIDLRTSTSQAVFRLQSGIC 203
Query: 1195 RLFSQFLWKSNFRQICTPKLTAGTSEGGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQ 1016
LF + L F +I TPK+ + SEGGA VF + Y K A LAQSPQL+KQM IC DF+
Sbjct: 204 HLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQMCICADFE 263
Query: 1015 RVFLVGPVFRAEDSYTHRHLCEFTGLDVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRE 836
+VF +GPVFRAEDS THRHL EF GLD+EM +HY EVM+ + V +F + E +
Sbjct: 264 KVFSIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIADTMVQIFKGLQERFQT 323
Query: 835 SLEAIRKQYPFEPLKYKKETLRLTFEEGIQMLKDAGIEVDPLGDLNTETERTLGKLVLEK 656
++ + KQ+P EP K+ + TLRL + E + ML++AG+E+ DL+T E+ LG LV EK
Sbjct: 324 EIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMGDEDDLSTPNEKLLGHLVKEK 383
Query: 655 YDTEFYILHRYPLAVRPFYTMPCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRAR 476
YDT+FYIL +YPLAVRPFYTMP P NP SNS+D+F+RGEEI+SGAQR+H P++L RA
Sbjct: 384 YDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERAL 443
Query: 475 ECGIDVNTISTYIDSFRYGAPPHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
GID+ I YIDSFR+GAPPH G G+GLERV MLF GL N+R+TS+FPRDP+RL P
Sbjct: 444 HHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501
>sp|P15178|SYDC_RAT Aspartate--tRNA ligase, cytoplasmic OS=Rattus norvegicus
GN=Dars PE=2 SV=1
Length = 501
Score = 473 bits (1217), Expect = 2e-132
Identities = 242/478 (50%), Positives = 323/478 (67%), Gaps = 8/478 (1%)
Frame = -3
Query: 1732 ITDLQSPQTPPTRLFNTVKSLGKEMEGESVWVRGRVFAIRPVAKKMCFFTVREMGSSVQC 1553
++ + Q P R+ VK L + E VWVR RV R K+ CF +R+ +VQ
Sbjct: 31 VSSMIQSQEKPDRVLVRVKDLTVQKADEVVWVRARVHTSRAKGKQ-CFLVLRQQQFNVQA 89
Query: 1552 VLSVAEGLVSAQMVKFAVGISKESFVDVEGVVSVPKAPITGASQQ-VEIQVRKIYCVNRA 1376
+++V + S QMVKFA I+KES +DVEG+V I +QQ VE+ V+KIY ++ A
Sbjct: 90 LVAVGDH-ASKQMVKFAANINKESIIDVEGIVRKVNQKIGSCTQQDVELHVQKIYVISLA 148
Query: 1375 APVLPISIEDASRSEAEIESALELGEQLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVL 1196
P LP+ ++DA R E E E + VNQDTRL+ R++D+RT +QAIF L+S +
Sbjct: 149 EPRLPLQLDDAIRPEVEGEE-----DGRATVNQDTRLDNRIIDLRTSTSQAIFHLQSGIC 203
Query: 1195 RLFSQFLWKSNFRQICTPKLTAGTSEGGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQ 1016
LF + L F +I TPK+ + SEGGA VF + Y K A LAQSPQL+KQM IC DF+
Sbjct: 204 HLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKSNAYLAQSPQLYKQMCICADFE 263
Query: 1015 RVFLVGPVFRAEDSYTHRHLCEFTGLDVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRE 836
+VF +GPVFRAEDS THRHL EF GLD+EM +HY EV++ + V +F + E +
Sbjct: 264 KVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIADTLVQIFKGLQERFQT 323
Query: 835 SLEAIRKQYPFEPLKYKKETLRLTFEEGIQMLKDAGIEVDPLGDLNTETERTLGKLVLEK 656
++ + KQ+P EP K+ + TLRL + E + ML++AG+E+D DL+T E+ LG+LV EK
Sbjct: 324 EIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMDDEEDLSTPNEKLLGRLVKEK 383
Query: 655 YDTEFYILHRYPLAVRPFYTMPCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRAR 476
YDT+FY+L +YPLAVRPFYTMP P NP SNS+D+F+RGEEI+SGAQR+H P++L RA
Sbjct: 384 YDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERAL 443
Query: 475 ECGIDVNTISTYIDSFRYGAPPHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
GID+ I YIDSFR+GAPPH G G+GLERV MLF GL N+R+TS+FPRDP+RL P
Sbjct: 444 HHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501
>sp|Q922B2|SYDC_MOUSE Aspartate--tRNA ligase, cytoplasmic OS=Mus musculus
GN=Dars PE=2 SV=2
Length = 501
Score = 473 bits (1216), Expect = 2e-132
Identities = 244/478 (51%), Positives = 323/478 (67%), Gaps = 8/478 (1%)
Frame = -3
Query: 1732 ITDLQSPQTPPTRLFNTVKSLGKEMEGESVWVRGRVFAIRPVAKKMCFFTVREMGSSVQC 1553
I+ + Q P R+ VK L + + VWVR RV R K+ CF +R+ +VQ
Sbjct: 31 ISSMIQSQEKPDRVLVRVKDLTVQKADDVVWVRARVHTSRAKGKQ-CFLVLRQQQFNVQA 89
Query: 1552 VLSVAEGLVSAQMVKFAVGISKESFVDVEGVVSVPKAPITGASQQ-VEIQVRKIYCVNRA 1376
+++V + S QMVKFA I+KES +DVEGVV I +QQ VE+ V+KIY ++ A
Sbjct: 90 LVAVGDH-ASKQMVKFAANINKESIIDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLA 148
Query: 1375 APVLPISIEDASRSEAEIESALELGEQLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVL 1196
P LP+ ++DA R E E E + VNQDTRL+ RV+D+RT +QAIF L+S +
Sbjct: 149 EPRLPLQLDDAIRPEVEGEE-----DGRATVNQDTRLDNRVIDLRTSTSQAIFRLQSGIC 203
Query: 1195 RLFSQFLWKSNFRQICTPKLTAGTSEGGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQ 1016
LF + L F +I TPK+ + SEGGA VF + Y K A LAQSPQL+KQM IC DF+
Sbjct: 204 HLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQMCICADFE 263
Query: 1015 RVFLVGPVFRAEDSYTHRHLCEFTGLDVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRE 836
+VF +GPVFRAEDS THRHL EF GLD+EM +HY EV++ + V +F + E +
Sbjct: 264 KVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIADTLVQIFKGLQERFQT 323
Query: 835 SLEAIRKQYPFEPLKYKKETLRLTFEEGIQMLKDAGIEVDPLGDLNTETERTLGKLVLEK 656
++ + KQ+P EP K+ + TLRL + E + ML++AG+E+D DL+T E+ LG+LV EK
Sbjct: 324 EIQTVSKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMDDEEDLSTPNEKLLGRLVKEK 383
Query: 655 YDTEFYILHRYPLAVRPFYTMPCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRAR 476
YDT+FY+L +YPLAVRPFYTMP P NP SNS+D+F+RGEEI+SGAQR+H P++L RA
Sbjct: 384 YDTDFYVLDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERAL 443
Query: 475 ECGIDVNTISTYIDSFRYGAPPHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
GID+ I YIDSFR+GAPPH G G+GLERV MLF GL N+R+TS+FPRDP+RL P
Sbjct: 444 HHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501
>sp|Q5R9I5|SYDC_PONAB Aspartate--tRNA ligase, cytoplasmic OS=Pongo abelii
GN=DARS PE=2 SV=1
Length = 501
Score = 471 bits (1211), Expect = 9e-132
Identities = 245/478 (51%), Positives = 321/478 (67%), Gaps = 8/478 (1%)
Frame = -3
Query: 1732 ITDLQSPQTPPTRLFNTVKSLGKEMEGESVWVRGRVFAIRPVAKKMCFFTVREMGSSVQC 1553
I+ + Q R+ V+ L + E VWVR RV R K+ CF +R+ +VQ
Sbjct: 31 ISSMIQSQEKSDRVLVRVRDLTIQKADEVVWVRARVHTSRAKGKQ-CFLVLRQQQFNVQA 89
Query: 1552 VLSVAEGLVSAQMVKFAVGISKESFVDVEGVVSVPKAPITGASQQ-VEIQVRKIYCVNRA 1376
+++V + S QMVKFA I+KES VDVEGVV I +QQ VE+ V+KIY ++ A
Sbjct: 90 LVAVGDH-ASKQMVKFAANINKESIVDVEGVVRKVNQKIESCTQQDVELHVQKIYVISLA 148
Query: 1375 APVLPISIEDASRSEAEIESALELGEQLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVL 1196
P LP+ ++DA R EAE E E VNQDTRL+ RV+D+RT +QA+F L+S +
Sbjct: 149 EPRLPLQLDDAVRPEAEGEE-----EGRATVNQDTRLDNRVIDLRTSTSQAVFRLQSGIC 203
Query: 1195 RLFSQFLWKSNFRQICTPKLTAGTSEGGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQ 1016
LF + L F +I TPK+ + SEGGA VF + Y K A LAQSPQL+KQM IC DF+
Sbjct: 204 HLFRETLINKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQMCICADFE 263
Query: 1015 RVFLVGPVFRAEDSYTHRHLCEFTGLDVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRE 836
+VF +GPVFRAEDS THRHL EF GLD+EM +HY EVM+ + V +F + E +
Sbjct: 264 KVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVMEEIADTMVQIFKGLQERFQT 323
Query: 835 SLEAIRKQYPFEPLKYKKETLRLTFEEGIQMLKDAGIEVDPLGDLNTETERTLGKLVLEK 656
++ + KQ+P EP K+ + TLRL + E + ML++AG+E+ DL+T E+ LG L+ EK
Sbjct: 324 EIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGVEMGDEDDLSTPNEKLLGHLIKEK 383
Query: 655 YDTEFYILHRYPLAVRPFYTMPCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRAR 476
YDT+FYIL +YPLAVRPFYTMP P NP SNS+D+F+RGEEI+SGAQR+H P++L RA
Sbjct: 384 YDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLLTERAL 443
Query: 475 ECGIDVNTISTYIDSFRYGAPPHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
GID+ I YIDSFR+GAPPH G G+GLERV MLF GL N+R+TS+FPRDP+RL P
Sbjct: 444 HHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501
>sp|Q3SYZ4|SYDC_BOVIN Aspartate--tRNA ligase, cytoplasmic OS=Bos taurus GN=DARS
PE=2 SV=1
Length = 501
Score = 470 bits (1207), Expect = 3e-131
Identities = 243/478 (50%), Positives = 321/478 (67%), Gaps = 8/478 (1%)
Frame = -3
Query: 1732 ITDLQSPQTPPTRLFNTVKSLGKEMEGESVWVRGRVFAIRPVAKKMCFFTVREMGSSVQC 1553
++ + Q P R+ + L + GE VWVR RV R K+ CF +R+ +VQ
Sbjct: 31 VSSMIQSQEKPDRVLVRISDLTVQKAGEVVWVRARVHTSRAKGKQ-CFLVLRQQQFNVQA 89
Query: 1552 VLSVAEGLVSAQMVKFAVGISKESFVDVEGVVSVPKAPITGASQQ-VEIQVRKIYCVNRA 1376
+++V + S QMVKFA I+KES VDVEGVV I +QQ VE+ V+KIY ++ A
Sbjct: 90 LVAVGDH-ASKQMVKFAANINKESIVDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISSA 148
Query: 1375 APVLPISIEDASRSEAEIESALELGEQLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVL 1196
P LP+ ++DA R E E E E VNQDTRL+ RV+D+RT +QAIF L+S +
Sbjct: 149 EPRLPLQLDDAVRPEVEGEE-----EGRATVNQDTRLDNRVIDLRTSTSQAIFRLQSGIC 203
Query: 1195 RLFSQFLWKSNFRQICTPKLTAGTSEGGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQ 1016
F + L F +I TPK+ + SEGGA VF + Y K A LAQSPQL+KQM IC DF+
Sbjct: 204 HPFRETLTNKGFVEIQTPKIISAASEGGANVFTVSYFKNNAYLAQSPQLYKQMCICADFE 263
Query: 1015 RVFLVGPVFRAEDSYTHRHLCEFTGLDVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRE 836
+VF +GPVFRAEDS THRHL EF GLD+EM +HY EV++ + V +F + + +
Sbjct: 264 KVFCIGPVFRAEDSNTHRHLTEFVGLDIEMAFNYHYHEVVEEIADTLVQIFKGLQKRFQT 323
Query: 835 SLEAIRKQYPFEPLKYKKETLRLTFEEGIQMLKDAGIEVDPLGDLNTETERTLGKLVLEK 656
++ + KQ+P EP K+ + TLRL + E + ML++AGIE+ DL+T E+ LG+LV EK
Sbjct: 324 EIQTVNKQFPCEPFKFLEPTLRLEYCEALAMLREAGIEMGDEEDLSTPNEKLLGRLVKEK 383
Query: 655 YDTEFYILHRYPLAVRPFYTMPCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRAR 476
YDT+FYIL +YPLAVRPFYTMP P NP SNS+D+F+RGEEI+SGAQR+H P+++ RA
Sbjct: 384 YDTDFYILDKYPLAVRPFYTMPDPRNPKQSNSYDMFMRGEEILSGAQRIHDPQLVTERAL 443
Query: 475 ECGIDVNTISTYIDSFRYGAPPHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
GID+ I YIDSFR+GAPPH G G+GLERV MLF GL N+R+TS+FPRDP+RL P
Sbjct: 444 HHGIDLEKIKAYIDSFRFGAPPHAGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501
>sp|P04802|SYDC_YEAST Aspartate--tRNA ligase, cytoplasmic OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) GN=DPS1 PE=1 SV=3
Length = 557
Score = 430 bits (1104), Expect = 2e-119
Identities = 237/495 (47%), Positives = 315/495 (63%), Gaps = 13/495 (2%)
Frame = -3
Query: 1765 DPLAANYGDTP-ITDLQSPQTPPTRLFNTVKSLGKEMEGESVWVRGRVFAIRPVAKKMCF 1589
D NYG P I S +T R+ K+ + E V R RV R + F
Sbjct: 69 DTAKDNYGKLPLIQSRDSDRTGQKRVKFVDLDEAKDSDKE-VLFRARVHNTRQQGATLAF 127
Query: 1588 FTVREMGSSVQ-CVLSVAEGLVSAQMVKFAVGISKESFVDVEGVVSVPKAPITGAS-QQV 1415
T+R+ S +Q V + EG +S MVK+A ++ ES V V G+V PI A+ Q +
Sbjct: 128 LTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIVLVRGIVKKVDEPIKSATVQNL 187
Query: 1414 EIQVRKIYCVNRAAPVLPISIEDASRSEAEIESALELGEQLVRVNQDTRLNYRVLDIRTP 1235
EI + KIY ++ LPI +EDASRSEAE E+A L VN DTRL+YRV+D+RT
Sbjct: 188 EIHITKIYTISETPEALPILLEDASRSEAEAEAA-----GLPVVNLDTRLDYRVIDLRTV 242
Query: 1234 ANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGGAAVFRLEYKKQPACLAQSP 1055
NQAIF +++ V LF ++L F ++ TPKL SEGG++VF + Y K A LAQSP
Sbjct: 243 TNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSVFEVTYFKGKAYLAQSP 302
Query: 1054 QLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDVEMEIKWHYSEVMDIVDTLF 875
Q +KQ I DF+RV+ +GPVFRAE+S THRH+ EFTGLD+EM + HY EV+D + LF
Sbjct: 303 QFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLSELF 362
Query: 874 VDMFNKINEECRESLEAIRKQYPFEPLKYKKE--TLRLTFEEGIQMLKDAGIEVDPLGDL 701
V +F+++ + +E +RKQYP E K K+ +RLT++EGI+ML+ AG E+ DL
Sbjct: 363 VFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGIEMLRAAGKEIGDFEDL 422
Query: 700 NTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTMPCPDNPAYSNSFDVFIRGEEIISG 521
+TE E+ LGKLV +KYDT+FYIL ++PL +RPFYTMP P NP YSNS+D F+RGEEI+SG
Sbjct: 423 STENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEILSG 482
Query: 520 AQRVHMPEMLESRARECGIDVNT--ISTYIDSFRYGAPPHGGFGVGLERVVMLFCGLDNI 347
AQR+H +L+ R + G+ + Y D F YG PPH G G+GLERVVM + L NI
Sbjct: 483 AQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNI 542
Query: 346 RKTSLFPRDPRRLEP 302
R+ SLFPRDP+RL P
Sbjct: 543 RRASLFPRDPKRLRP 557
>sp|Q03577|SYDC_CAEEL Aspartate--tRNA ligase, cytoplasmic OS=Caenorhabditis
elegans GN=drs-1 PE=2 SV=1
Length = 531
Score = 427 bits (1097), Expect = 2e-118
Identities = 222/465 (47%), Positives = 305/465 (65%), Gaps = 4/465 (0%)
Frame = -3
Query: 1690 FNTVKSLGKEMEGESVWVRGRVFAIRPVAKKMCFFTVREMGSSVQCVLSVAEGLVSAQMV 1511
F VK + + VWVRGR+ R K CF +R+ +VQ + + E +S QM+
Sbjct: 69 FLKVKEINVSNATKDVWVRGRIHTTRSKGKN-CFLVLRQGVYTVQVAMFMNE-KISKQML 126
Query: 1510 KFAVGISKESFVDVEGVVSVPKAPITGASQQ-VEIQVRKIYCVNRAAPVLPISIEDAS-R 1337
KF ISKES VDV ++ PI +Q+ VE+ ++++ V+ +AP LP+ IEDAS R
Sbjct: 127 KFVSSISKESIVDVYATINKVDNPIESCTQKDVELLAQQVFVVSTSAPKLPLQIEDASRR 186
Query: 1336 SEAEIESALELGEQLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFR 1157
+ + E A E QL VN DTRL+ RV+D+RTP + AIF +++ + F L F
Sbjct: 187 APTDEEKASEQENQLAVVNLDTRLDNRVIDLRTPTSHAIFRIQAGICNQFRNILDVRGFV 246
Query: 1156 QICTPKLTAGTSEGGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAED 977
+I PK+ + SEGGA VF + Y K A LAQSPQL+KQMAI GDF++V+ +GPVFRAED
Sbjct: 247 EIMAPKIISAPSEGGANVFEVSYFKGSAYLAQSPQLYKQMAIAGDFEKVYTIGPVFRAED 306
Query: 976 SYTHRHLCEFTGLDVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEP 797
S THRH+ EF GLD+EM +HY EVM+ + + MF + + ++ + A+ QYP EP
Sbjct: 307 SNTHRHMTEFVGLDLEMAFNFHYHEVMETIAEVLTQMFKGLQQNYQDEIAAVGNQYPAEP 366
Query: 796 LKYKKETLRLTFEEGIQMLKDAGIEVDPLGDLNTETERTLGKLVLEKYDTEFYILHRYPL 617
++ + L L + + I +L++ GIE+ DL+T E+ LGKLV EKY T+FY+L ++PL
Sbjct: 367 FQFCEPPLILKYPDAITLLRENGIEIGDEDDLSTPVEKFLGKLVKEKYSTDFYVLDKFPL 426
Query: 616 AVRPFYTMPCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYI 437
+VRPFYTMP + YSNS+D+F+RGEEI+SGAQR+H +ML RA+ +D+ I +YI
Sbjct: 427 SVRPFYTMPDAHDERYSNSYDMFMRGEEILSGAQRIHDADMLVERAKHHQVDLAKIQSYI 486
Query: 436 DSFRYGAPPHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
DSF+YG PPH G G+GLERV MLF GL NIR SLFPRDP+RL P
Sbjct: 487 DSFKYGCPPHAGGGIGLERVTMLFLGLHNIRLASLFPRDPKRLTP 531
>sp|Q75JQ1|SYDC1_DICDI Aspartate--tRNA ligase, cytoplasmic 1 OS=Dictyostelium
discoideum GN=aspS1 PE=3 SV=1
Length = 576
Score = 339 bits (869), Expect = 4e-092
Identities = 170/337 (50%), Positives = 226/337 (67%), Gaps = 8/337 (2%)
Frame = -3
Query: 1297 QLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSE 1118
+ V V+Q+ RL+ R LD+R PA+Q+IF L+S V LF + L F +I +PK+ + SE
Sbjct: 243 KFVNVSQEKRLDNRALDLRVPAHQSIFRLQSGVCTLFREQLLGEGFIEIHSPKIISAASE 302
Query: 1117 GGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGL 938
GA+VF+L Y A LAQSPQL+KQMAIC DF +VF +GPVFRAE+S THRHL EF GL
Sbjct: 303 SGASVFKLNYFNTHAYLAQSPQLYKQMAICADFNKVFEIGPVFRAENSNTHRHLTEFVGL 362
Query: 937 DVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPLKYKKETLRLTFE 758
D+EM K HY E +D +D L +F + + +E++ QYPFEP K+ + R TF+
Sbjct: 363 DLEMTFKDHYHEALDTLDRLMTSIFRGLETRFAKEIESVNTQYPFEPFKFTYPSPRFTFD 422
Query: 757 EGIQMLKDAGIEVDP-----LGDLNTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTM 593
E ML + DP D NT E+ LGK++ EK+ +F+I+ ++ + VRPFYTM
Sbjct: 423 EAAAMLAELN---DPDYIVKDNDFNTRQEKRLGKIIKEKFGVDFFIVDKFHVEVRPFYTM 479
Query: 592 PCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFRYGAP 413
P P+NP ++N++D+F+RGEEI SGAQR+H PE+LE A+ G+ + I YIDSF+YG
Sbjct: 480 PDPNNPQWANAYDLFMRGEEICSGAQRIHDPELLEKSAKSHGVVIEDIQGYIDSFKYGCS 539
Query: 412 PHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
H G GVGLERVVML+ GL NIRK S PRDP RL P
Sbjct: 540 QHAGGGVGLERVVMLYLGLGNIRKASFCPRDPTRLTP 576
>sp|Q8SRQ8|SYDC_ENCCU Probable aspartate--tRNA ligase, cytoplasmic
OS=Encephalitozoon cuniculi (strain GB-M1) GN=ECU06_0790 PE=3 SV=1
Length = 473
Score = 305 bits (780), Expect = 9e-082
Identities = 171/462 (37%), Positives = 277/462 (59%), Gaps = 10/462 (2%)
Frame = -3
Query: 1681 VKSLGKEMEGESVWVRGRVFAIRPVAKKMCFFTVREMGSSVQCVL-SVAEGLVSAQMVKF 1505
++ L ++G V VRG VF K F +R+ G +VQC+ +G M +F
Sbjct: 16 IRDLDGSLDGRCVSVRGFVFK-SSCTGKYIFIVLRDGGCTVQCMCEKPTDGSGGLTMPEF 74
Query: 1504 AV--GISKESFVDVEGVVSVPKAPITGASQQ-VEIQVRKIYCVNRAAPVLPISIEDASRS 1334
+ ++ ES++++ G V I+G S++ +E+++ ++ A LP +++D S +
Sbjct: 75 SSLRKVTHESYIEIRGRVVKQGMEISGCSKKDIEVRILGFRVLSIADKSLPFAMKDVSAT 134
Query: 1333 EAEIESALELGEQLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQ 1154
E E L V RL+ R +D+R P +A F + V+ F +L ++ F +
Sbjct: 135 AEEREK----NPTLQNVAYHIRLDNRAMDLRAPQTRATFRVVDGVMFFFRTYLRQNGFME 190
Query: 1153 ICTPKLTAGTSEGGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDS 974
I T KL +SEGGA +F ++Y K+ A +AQSPQL+KQMAI G F+RV+ +G V+RAE+S
Sbjct: 191 IKTSKLIGSSSEGGANLFSVDYFKRKAFMAQSPQLYKQMAIVGGFKRVYEIGHVYRAEES 250
Query: 973 YTHRHLCEFTGLDVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPL 794
+R+L EF GLD+EMEI Y++V+ + ++ V +F+ + +E E LE IR + FE L
Sbjct: 251 NINRYLSEFVGLDMEMEICTDYNDVIRFIHSMLVSIFDNLKKEYGEELETIRAFHAFEDL 310
Query: 793 KYKKETLRLTFEEGIQMLKDAGIEVDPLGDLNTETERTLGKLVLEKYDTEFYILHRYPLA 614
KY+++ + LT E + +L + G+E+ D N+E+E+ LG +V + + +++ YP++
Sbjct: 311 KYRRDPVVLTHRECVDLLLNEGVEMGYEDDFNSESEKKLGSVVRRMHGVDIFVIKDYPIS 370
Query: 613 VRPFYTMPCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYID 434
RPFYT + + S+D +RG+EI+SGAQRV + + L E GI +++ Y++
Sbjct: 371 TRPFYTYR-DEEKGITRSYDFILRGQEILSGAQRVSIYKDLVKYVEEHGISPSSLGGYLE 429
Query: 433 SFRYGAPPHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRL 308
SF+YGAPPHGG G+GLER++ + G+ +IR SLFPRDP RL
Sbjct: 430 SFKYGAPPHGGCGIGLERLMKAYFGMGDIRCFSLFPRDPNRL 471
>sp|B7XHQ4|SYDC_ENTBH Probable aspartate--tRNA ligase, cytoplasmic
OS=Enterocytozoon bieneusi (strain H348) GN=EBI_21705 PE=3 SV=1
Length = 474
Score = 290 bits (742), Expect = 2e-077
Identities = 158/459 (34%), Positives = 263/459 (57%), Gaps = 9/459 (1%)
Frame = -3
Query: 1681 VKSLGKEMEGESVWVRGRVFAIRPVAKKMCFFTVREMGSSVQCVLSVAEGLVSAQMVKFA 1502
+++L M G + +RG + +I + ++ F +R+ VQC++ + + S
Sbjct: 22 IQNLTDNMNGTVIRIRGFIESITSCSSQI-FILLRDRLEKVQCIIFKSTNVSSIYEFSRL 80
Query: 1501 VGISKESFVDVEGVVSVPKAPITGASQQ-VEIQVRKIYCVNRAAPVLPISIEDASRSEAE 1325
+ ESF+++EG V + PI A++Q +EI + + + LP ++D + E
Sbjct: 81 KKLPLESFIEIEGQVVFAEIPIKRATKQNIEIVISTLNILGPVVSKLPFQLKDCKIAGKE 140
Query: 1324 IESALELGEQLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICT 1145
++ + V + RL+ R LD R P Q+I + + F +L F +I T
Sbjct: 141 SDT------NTITVGYNLRLDNRFLDFRLPVTQSIIKIIDQTMYTFRTYLRTHEFIEIKT 194
Query: 1144 PKLTAGTSEGGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTH 965
K+ SEGGA +F L Y +PA LAQSPQL+KQ+AI G +RV+ +G V+RAE S +
Sbjct: 195 SKIIQSGSEGGANLFSLNYFNKPAYLAQSPQLYKQLAIIGGLKRVYEIGHVYRAEVSNIN 254
Query: 964 RHLCEFTGLDVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPLKYK 785
R+L EF GLD+EME++ Y + + + +LF+++F E ++ LE IR+ Y F LKY+
Sbjct: 255 RYLSEFVGLDIEMEMETTYIDFIHFLHSLFINIFESFKNEMKKELEIIRQYYEFVDLKYR 314
Query: 784 KETLRLTFEEGIQMLKDAGIEVDPLGDLNTETERTLGKLVLEKYDTEFYILHRYPLAVRP 605
+ +T+++ + MLK I++D D + E ER LGK++ +K D + + + YP ++R
Sbjct: 315 STPIIITYKDAVDMLKSKNIQIDYGCDFSREHERILGKIIKDKEDIDIFTIIDYPSSIRA 374
Query: 604 FYTMPCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFR 425
FY+ + + S+D +RGEEI+SGAQR + + L++ + G++ + Y+++F+
Sbjct: 375 FYSY-IDETTKLTRSYDFIVRGEEILSGAQRENRYDYLKNAVIDKGLNPENLKNYLEAFK 433
Query: 424 YGAPPHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRL 308
YGAPPH G G+GLER + + G D+IR SLFPRDP R+
Sbjct: 434 YGAPPHIGCGIGLERFLKAYFGFDDIRYFSLFPRDPNRI 472
>sp|O74407|SYDC_SCHPO Aspartate--tRNA ligase, cytoplasmic OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) GN=dps1 PE=1 SV=1
Length = 580
Score = 271 bits (692), Expect = 1e-071
Identities = 147/352 (41%), Positives = 218/352 (61%), Gaps = 9/352 (2%)
Frame = -3
Query: 1765 DPLAANYGDTPITDLQSPQTPPTRLFNTVKSLGKEMEGESVWVRGRVFAIRPVAKKMCFF 1586
D A YGD P L P R + + + + +G++V +R RV+ R KMCFF
Sbjct: 70 DYSAGKYGDLP---LNRSTARPGRTYTQISDISAKNDGQTVLLRARVYTSRLQGNKMCFF 126
Query: 1585 TVREMGSSVQCVLSVAEGLVSAQMVKFAVGISKESFVDVEGVVSVPKAPITGAS-QQVEI 1409
++R+ ++Q + V + +S QMVK+ IS ES V VEG+V I A+ Q EI
Sbjct: 127 SLRQKYDTIQALAVVNKDTISKQMVKWCGSISLESIVLVEGIVKKSPEIIKSATVQDAEI 186
Query: 1408 QVRKIYCVNRAAPVLPISIEDASRSEAEI----ESALELGEQLVRVNQDTRLNYRVLDIR 1241
+ IY ++ LP +EDA RSE +I E+A E + VRVN DTRL+ RVLD+R
Sbjct: 187 HISSIYVISPIKKNLPFLVEDAGRSEEQIRESEENAAEGDSKFVRVNLDTRLDNRVLDLR 246
Query: 1240 TPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGGAAVFRLEYKKQPACLAQ 1061
TP NQAIF +++ + + F +FL ++F +I TPK++ +SEGG+ VF+++Y K L+Q
Sbjct: 247 TPTNQAIFDIQAGICQAFREFLLSNSFNEIHTPKMSGASSEGGSNVFKIQYFKTDGFLSQ 306
Query: 1060 SPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDVEMEIKWHYSEVMDIVDT 881
SPQL+KQM I D +RVF +GPVFRAEDS T+RH+ EFTGLD+EM HY EVM+ ++
Sbjct: 307 SPQLYKQMLIAADRERVFEIGPVFRAEDSNTYRHMTEFTGLDLEMAFNEHYHEVMEFIEK 366
Query: 880 LFVDMFNKINEECRESLEAIRKQYPFEP-LKYKKETLRLTFEEGIQMLKDAG 728
LF+ +F I E+ + + +R+QYP E + + +R F++ +++LK+AG
Sbjct: 367 LFLYIFKTIREKYAKQVAVVRQQYPSEDFILPDADRIRFHFKDAVKLLKEAG 418
>sp|Q9V036|SYD_PYRAB Aspartate--tRNA ligase OS=Pyrococcus abyssi (strain GE5 /
Orsay) GN=aspS PE=3 SV=1
Length = 438
Score = 258 bits (659), Expect = 9e-068
Identities = 136/330 (41%), Positives = 196/330 (59%), Gaps = 4/330 (1%)
Frame = -3
Query: 1291 VRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGG 1112
V+ DTRL+ R +D+R P +IF + S V R +F +K F +I TPK+ A +EGG
Sbjct: 113 VKAELDTRLDNRFMDLRNPRVMSIFKIRSSVFRATREFFYKEGFIEIHTPKIIATATEGG 172
Query: 1111 AAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDV 932
+F L+Y + A LAQSPQL+KQM + +VF +GP+FRAE+ T RHL E +D
Sbjct: 173 TELFPLKYFENDAFLAQSPQLYKQMMMSTGLDKVFEIGPIFRAEEHNTTRHLNEAWSIDA 232
Query: 931 EMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPLKYKKETLRLTFEEG 752
EM EVMD+++ L + + N + E + L+ + FE + KK R+T++E
Sbjct: 233 EMAFIESEEEVMDLLERLILYVINYVRENNEKELKILE----FELNEPKKPFPRITYDEA 288
Query: 751 IQMLKDAGIEVDPLGDLNTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTMPCPDNPA 572
+++L D G E+ D++TE E+ LGK +LE E Y ++RYP +PFY M D P
Sbjct: 289 LEILSDLGKEIPWGEDIDTEGEKLLGKYMLENEGAELYFIYRYPSEAKPFYIMKYEDKPE 348
Query: 571 YSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFRYGAPPHGGFGV 392
+FD+ RG EI SG QR H ++L + RE G++ + Y+ +F YG PPHGGFG+
Sbjct: 349 VCKAFDLEYRGVEISSGGQREHRHDILVEQIREKGLNPESFEFYLRAFEYGMPPHGGFGL 408
Query: 391 GLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
G ER++M + NIR+ LFPRD RRL P
Sbjct: 409 GAERLIMRMLDIGNIREVILFPRDRRRLVP 438
>sp|O58776|SYD_PYRHO Aspartate--tRNA ligase OS=Pyrococcus horikoshii (strain
ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) GN=aspS PE=3
SV=1
Length = 438
Score = 248 bits (632), Expect = 1e-064
Identities = 129/330 (39%), Positives = 194/330 (58%), Gaps = 4/330 (1%)
Frame = -3
Query: 1291 VRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGG 1112
V+ DTRL+ R +D+R P AIF + S V R +F + F +I TPK+ A +EGG
Sbjct: 113 VKAELDTRLDNRFMDLRNPKVMAIFKIRSSVFRAVREFFYSEGFIEIHTPKIIATATEGG 172
Query: 1111 AAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDV 932
+F L+Y ++ A LAQSPQL+KQM + +VF + P+FRAE+ T RHL E +D
Sbjct: 173 TELFPLKYFERDAFLAQSPQLYKQMMMATGLDKVFEIAPIFRAEEHNTTRHLNEAWSIDA 232
Query: 931 EMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPLKYKKETLRLTFEEG 752
EM + EVMD+++ L + N + E + L+ + FE + K+ R+T+++
Sbjct: 233 EMAFIENEGEVMDLLERLISYVINYVREHNEKELKTLE----FELNEPKRPFPRITYDKA 288
Query: 751 IQMLKDAGIEVDPLGDLNTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTMPCPDNPA 572
+++L D G E+ D++TE E+ LGK + E + Y ++RYP +PFY M + P
Sbjct: 289 LEILSDLGKEIPWGEDIDTEGEKLLGKYMAENEGADLYFIYRYPSEAKPFYIMKYDEKPE 348
Query: 571 YSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFRYGAPPHGGFGV 392
+FD+ RG EI SG QR H ++L + +E G++ + Y+ +F YG PPHGGFG+
Sbjct: 349 VCRAFDLEYRGVEISSGGQREHRHDVLLEQIKEKGLNPKSFEFYLKAFEYGMPPHGGFGL 408
Query: 391 GLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
G ER++M + NIR+ LFPRD RRL P
Sbjct: 409 GAERLIMRMLDIGNIREVILFPRDRRRLVP 438
>sp|Q9Y9U7|SYD_AERPE Aspartate--tRNA ligase OS=Aeropyrum pernix (strain ATCC
700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) GN=aspS PE=3 SV=2
Length = 442
Score = 247 bits (629), Expect = 3e-064
Identities = 145/397 (36%), Positives = 215/397 (54%), Gaps = 10/397 (2%)
Frame = -3
Query: 1471 VEGVVSVPKAPITGASQQVEIQVRKIYCVN---RAAPV---LPISIEDASRSEAEIESAL 1310
++ V ++P ++++ + CV R AP + + +E +E
Sbjct: 49 IQATVKRGESPEDALRAAEDLKLESVVCVEGELRQAPTREGVEVKVERLEVLSTPVEPLP 108
Query: 1309 ELGEQLVRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTA 1130
E + + TRL YR LDIR P AIF LE+ V ++F + W F +I TPK+ A
Sbjct: 109 LEVEGSEKASLPTRLKYRWLDIRNPMVSAIFELEAMVAKVFRDYYWSQGFVEIFTPKIVA 168
Query: 1129 GTSEGGAAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCE 950
+E GA VF + Y + A LAQSPQ +KQ A+ +RVF +GPVFRAE +T RHL E
Sbjct: 169 AGTESGAEVFPVVYFDKTAFLAQSPQFYKQFAVIAGLERVFEIGPVFRAEPHHTSRHLNE 228
Query: 949 FTGLDVEMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPLK-YKKETL 773
+ LD+E+ Y++VM+ V+ + + E+ R LE + P P K L
Sbjct: 229 YHSLDIEVGFIESYNDVMNYVEGFMRAIVRMLEEDGRRVLELYGVELPRIPASGIPKIPL 288
Query: 772 RLTFEEGIQMLKDAGIEVDPLGDLNTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTM 593
R +E + + G +V+ DL++E ER +G E+ D++F + YP VRPFYTM
Sbjct: 289 RKAYE---ILEEKYGKKVEYGEDLDSEGERLMGAYAGEELDSDFVFIVEYPWKVRPFYTM 345
Query: 592 PCPDNPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFRYGAP 413
D P+++ SFD+ RG EI++G QR H L R+ G+D + Y+D F++GAP
Sbjct: 346 RKDDEPSWTYSFDLLYRGLEIVTGGQREHRYHRLLENLRDKGLDAESFQFYLDFFKHGAP 405
Query: 412 PHGGFGVGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
PHGG G+GLER+VM L+NIR+ + PRD R+ P
Sbjct: 406 PHGGAGMGLERIVMQTLKLENIREARMLPRDTERITP 442
>sp|Q8TQ68|SYD_METAC Aspartate--tRNA ligase OS=Methanosarcina acetivorans
(strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) GN=aspS PE=3 SV=1
Length = 444
Score = 246 bits (626), Expect = 6e-064
Identities = 132/331 (39%), Positives = 193/331 (58%), Gaps = 6/331 (1%)
Frame = -3
Query: 1291 VRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGG 1112
V DTRL+ R +D+R A+F + + L+ ++ K+ F + TPK+ A +EGG
Sbjct: 119 VEAELDTRLDSRFIDLRRAETTAVFKIRHEALQAIREYFVKNKFIETATPKVVATATEGG 178
Query: 1111 AAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDV 932
A+F + Y + A L QSPQL KQ+ + G F RVF +GP+FRAE+ T RHL E T +DV
Sbjct: 179 TALFPITYFDREAFLNQSPQLFKQILMGGGFDRVFEIGPIFRAEEHDTRRHLNEATSIDV 238
Query: 931 EMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPLKYKKETLRLTFEEG 752
E+ H+ +VM+I++ L ++ ++ E C+ SLE + + K L+LT++E
Sbjct: 239 EVSFADHF-DVMEILENLVAHIYTRVIENCKASLEILGVELKVP----KTPFLKLTYDEV 293
Query: 751 IQMLKDAGIEVDPLG-DLNTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTMPCPDNP 575
I+++ E G DL T E T+G V E Y + +P ++PFY MP D P
Sbjct: 294 IEIVNSRCEEKMHWGDDLGTLGEHTVGNYVYETTGESHYFIIDWPTEIKPFYAMPYEDRP 353
Query: 574 AYSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFRYGAPPHGGFG 395
+S SFD+ R E+ SGAQR+H+ E+L+SR G++ + Y+ +F YG PPH G+G
Sbjct: 354 EFSKSFDMMHRTMELSSGAQRIHISELLKSRIESQGLNPDGFEFYLKAFEYGMPPHAGWG 413
Query: 394 VGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
+G ER VM G +NIR T LFPRD RRL P
Sbjct: 414 MGCERFVMTMLGTENIRDTVLFPRDRRRLSP 444
>sp|Q8U2G6|SYD_PYRFU Aspartate--tRNA ligase OS=Pyrococcus furiosus (strain ATCC
43587 / DSM 3638 / JCM 8422 / Vc1) GN=aspS PE=3 SV=1
Length = 438
Score = 243 bits (620), Expect = 3e-063
Identities = 127/330 (38%), Positives = 193/330 (58%), Gaps = 4/330 (1%)
Frame = -3
Query: 1291 VRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGG 1112
V+ DTRL+ R +D+R P AIF + S+V R +F + F +I TPK+ A +EGG
Sbjct: 113 VKAELDTRLDNRFIDLRNPKVMAIFKIRSNVFRAIREFFYNEGFIEIHTPKIIATATEGG 172
Query: 1111 AAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDV 932
+F ++Y + A LAQSPQL+KQ+ + +VF P+FRAE+ T RHL E +D
Sbjct: 173 TELFPIKYFENDAFLAQSPQLYKQIMMATGLDKVFETAPIFRAEEHNTTRHLNEAWSIDA 232
Query: 931 EMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPLKYKKETLRLTFEEG 752
E+ + EVMD+++ L V N + E L+ + FE + K+ R+T+++
Sbjct: 233 EIAFIENEEEVMDVLENLVVYAINYVREHNERELKILE----FELEEPKQPFPRVTYDKA 288
Query: 751 IQMLKDAGIEVDPLGDLNTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTMPCPDNPA 572
+++L D G E+ D++TE E+ LGK + E E Y +++YP +PFY M + P
Sbjct: 289 LEILSDLGKEIPWGEDIDTEGEKLLGKYMSENEGVELYFIYKYPSEAKPFYIMKYDEKPE 348
Query: 571 YSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFRYGAPPHGGFGV 392
+FD+ RG EI SG QR H E+L + +E G++ + Y+ +F+YG PPHGGFG+
Sbjct: 349 ICRAFDLEYRGIEISSGGQREHRYEVLLEQIKEKGLNPESFEFYLKAFKYGMPPHGGFGL 408
Query: 391 GLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
G ER++M + NIR+ LFPRD +RL P
Sbjct: 409 GAERLIMRMLNIGNIREVILFPRDRKRLIP 438
>sp|Q466Y5|SYD_METBF Aspartate--tRNA ligase OS=Methanosarcina barkeri (strain
Fusaro / DSM 804) GN=aspS PE=3 SV=1
Length = 444
Score = 243 bits (618), Expect = 5e-063
Identities = 132/333 (39%), Positives = 192/333 (57%), Gaps = 10/333 (3%)
Frame = -3
Query: 1291 VRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGG 1112
V DTRL+ R +D+R A+F + L+ ++ ++ F + TPK+ A +EGG
Sbjct: 119 VEAELDTRLDSRFIDLRRAETTAVFKIRHQALQATREYFVQNGFIETATPKVVATATEGG 178
Query: 1111 AAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDV 932
A+F + Y + A L QSPQL KQ+ + G F RVF +GP+FRAE+ T RHL E T +DV
Sbjct: 179 TALFPITYFDREAFLNQSPQLFKQILMSGGFDRVFEIGPIFRAEEHDTRRHLNEATSIDV 238
Query: 931 EMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLE--AIRKQYPFEPLKYKKETLRLTFE 758
E+ H+ +VM+I++ L ++ ++ E+C+ SLE I + P P L+LT+
Sbjct: 239 EVSFADHF-DVMEILENLVAYVYAQVIEKCKPSLETLGIELKVPKTPF------LKLTYN 291
Query: 757 EGIQMLKDAGIEVDPLG-DLNTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTMPCPD 581
E I+++ E G DL T E +G V E Y + +P ++PFY MP D
Sbjct: 292 EVIEIINARSEEKMHWGDDLGTFGEHIVGNYVYETTGESHYFIIDWPTEIKPFYAMPYED 351
Query: 580 NPAYSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFRYGAPPHGG 401
P YS SFD+ R E+ SGAQR+H+P++L+SR G++ Y+ +F YG PPH G
Sbjct: 352 RPEYSKSFDMMHRTMELSSGAQRIHIPDLLKSRIESQGLNPEGFEFYLKAFEYGMPPHAG 411
Query: 400 FGVGLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
+G+G ER +M G +NIR T LFPRD RRL P
Sbjct: 412 WGMGCERFIMTMLGTENIRDTVLFPRDRRRLSP 444
>sp|Q52428|SYD_PYRKO Aspartate--tRNA ligase OS=Pyrococcus kodakaraensis (strain
ATCC BAA-918 / JCM 12380 / KOD1) GN=aspS PE=1 SV=2
Length = 438
Score = 237 bits (603), Expect = 3e-061
Identities = 126/330 (38%), Positives = 190/330 (57%), Gaps = 4/330 (1%)
Frame = -3
Query: 1291 VRVNQDTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGG 1112
V+ DTRL+ R +D+R P AIF + S V + F ++ F +I TPK+ A +EGG
Sbjct: 113 VKAELDTRLDNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGG 172
Query: 1111 AAVFRLEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDV 932
+F ++Y ++ A LAQSPQL+KQ+ + RV+ + P+FRAE+ T RHL E +D
Sbjct: 173 TELFPMKYFEEDAFLAQSPQLYKQIMMASGLDRVYEIAPIFRAEEHNTTRHLNEAWSIDS 232
Query: 931 EMEIKWHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPLKYKKETLRLTFEEG 752
EM EVM ++ L N + E + L+ + FE + K R+++++
Sbjct: 233 EMAFIEDEEEVMSFLERLVAHAINYVREHNAKELDILN----FELEEPKLPFPRVSYDKA 288
Query: 751 IQMLKDAGIEVDPLGDLNTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTMPCPDNPA 572
+++L D G E+ D++TE ER LGK ++E + Y L++YP +PFY M + P
Sbjct: 289 LEILGDLGKEIPWGEDIDTEGERLLGKYMMENENAPLYFLYQYPSEAKPFYIMKYDNKPE 348
Query: 571 YSNSFDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFRYGAPPHGGFGV 392
+FD+ RG EI SG QR H ++L + +E G++ + Y+ +FRYG PPHGGFG+
Sbjct: 349 ICRAFDLEYRGVEISSGGQREHRHDILVEQIKEKGLNPESFEFYLKAFRYGMPPHGGFGL 408
Query: 391 GLERVVMLFCGLDNIRKTSLFPRDPRRLEP 302
G ER++ L NIR+ LFPRD RRL P
Sbjct: 409 GAERLIKQMLDLPNIREVILFPRDRRRLTP 438
>sp|Q12XU7|SYD_METBU Aspartate--tRNA ligase OS=Methanococcoides burtonii (strain
DSM 6242) GN=aspS PE=3 SV=1
Length = 443
Score = 235 bits (599), Expect = 9e-061
Identities = 124/326 (38%), Positives = 193/326 (59%), Gaps = 6/326 (1%)
Frame = -3
Query: 1276 DTRLNYRVLDIRTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGGAAVFR 1097
DTRL+ R +D+R AIF + +VLR FL K + + C+PK+ A +EGG ++F
Sbjct: 123 DTRLDSRFMDLRRERTTAIFKIRHEVLRAVRDFLSKDGYIETCSPKVVATATEGGTSLFP 182
Query: 1096 LEYKKQPACLAQSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDVEMEIK 917
+ Y + A L QSPQL KQ+ + G +VF +GP+FRAE+ T RHL E T +D+E
Sbjct: 183 ITYFDREAFLNQSPQLFKQILMSGGLDKVFEIGPIFRAEEHDTRRHLNEATSIDIEASFL 242
Query: 916 WHYSEVMDIVDTLFVDMFNKINEECRESLEAIRKQYPFEPLKYKKETLRLTFEEGIQMLK 737
H+ +VM++++ + ++ ++ E SL+A+ E K +++ + + I ++
Sbjct: 243 DHF-DVMEVLEDMVAYVYEQVIENEAASLKAL----DIELSVPKTPFMKVPYSQAIDIVN 297
Query: 736 DAGIE-VDPLGDLNTETERTLGKLVLEKYDTEFYILHRYPLAVRPFYTMPCPDNPAYSNS 560
E V+ GDL T E T+G+ V ++ Y + +P ++PFY MP DNP S S
Sbjct: 298 AESEETVEWGGDLGTVAEHTIGEHVFKETGESHYFITDWPTEIKPFYAMPYEDNPLISKS 357
Query: 559 FDVFIRGEEIISGAQRVHMPEMLESRARECGIDVNTISTYIDSFRYGAPPHGGFGVGLER 380
FD+ R E+ SGAQR+H+ +ML++R G+D + Y+ +F+YG PPH G+G+G ER
Sbjct: 358 FDMMHRTMELSSGAQRIHIHDMLKARIESQGLDSDGFDFYLRAFKYGMPPHSGWGIGCER 417
Query: 379 VVMLFCGLDNIRKTSLFPRDPRRLEP 302
+VM ++NIR T LFPRD +RL P
Sbjct: 418 LVMTMLSVENIRDTVLFPRDRKRLSP 443
>sp|Q8TXG4|SYD_METKA Aspartate--tRNA ligase OS=Methanopyrus kandleri (strain
AV19 / DSM 6324 / JCM 9639 / NBRC 100938) GN=aspS PE=3 SV=1
Length = 431
Score = 160 bits (404), Expect = 3e-038
Identities = 97/257 (37%), Positives = 147/257 (57%), Gaps = 11/257 (4%)
Frame = -3
Query: 1411 IQVRKIYCVNRAAP----VLPISIEDASRSEAEIESALELGEQLVRVNQDTRLNYRVLDI 1244
I+V N AP V+P IE S S+ + G+ V + DTRL+ RVLD+
Sbjct: 72 IRVEGTVQANEKAPGGVEVIPQRIEVLSESDTHLPLD-PTGK--VDADLDTRLDARVLDL 128
Query: 1243 RTPANQAIFSLESDVLRLFSQFLWKSNFRQICTPKLTAGTSEGGAAVFRLEYKKQPACLA 1064
R QAIF + + V +FL + F ++ TPK+ A +EGG +F + Y ++ A LA
Sbjct: 129 RREEPQAIFKIRNVVTTAIREFLEERGFIEVHTPKIIASATEGGTELFPVVYFERDAYLA 188
Query: 1063 QSPQLHKQMAICGDFQRVFLVGPVFRAEDSYTHRHLCEFTGLDVEMEIKWHYSEVMDIVD 884
QSPQL+KQM + F+RV+ +GP+FRAE+ T RHL E +D+EM +VM +++
Sbjct: 189 QSPQLYKQMLMAAGFERVYEIGPIFRAEEHNTRRHLNEAISVDIEMSFIESEEDVMRVLE 248
Query: 883 TLFVDMFNKINEECRESLEAIRKQYPFEPLKYKKETLRLTFEEGIQMLKDAGIEVDPLGD 704
L +F K+ EEC + LEA+ ++ P ++ R+T+EE + +L + GIEV+ D
Sbjct: 249 ELLAHVFRKVREECEKELEALDRELPELETPFE----RITYEETLDLLSEHGIEVEWGED 304
Query: 703 LNTETERTLGKLVLEKY 653
L TE ER LG++ E +
Sbjct: 305 LPTEAERKLGEIFEEPF 321
Database: Uniprot/SwissProt
Posted date: Thu Sep 27 17:53:50 2012
Number of letters in database: 190,795,139
Number of sequences in database: 537,505
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 168,416,788,647
Number of Sequences: 537505
Number of Extensions: 168416788647
Number of Successful Extensions: 999195609
Number of sequences better than 0.0: 0
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