SwissProt blast output of UN86951
BLASTX 7.6.2
Query= UN86951 /QuerySize=3110
(3109 letters)
Database: Uniprot/SwissProt;
537,505 sequences; 190,795,139 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Ara... 359 1e-097
sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase dr... 242 1e-062
sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase dr... 236 1e-060
sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase dr... 233 1e-059
sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase dr... 228 2e-058
sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/r... 219 1e-055
sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dic... 214 5e-054
sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/r... 211 4e-053
sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dic... 204 4e-051
sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/r... 204 4e-051
sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dic... 198 4e-049
sp|Q2MHE4|HT1_ARATH Serine/threonine-protein kinase HT1 OS=Arabi... 189 2e-046
sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase ki... 163 1e-038
sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase ki... 163 1e-038
sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kina... 162 2e-038
sp|A8X775|DLK1_CAEBR Mitogen-activated protein kinase kinase kin... 150 7e-035
sp|Q869X3|Y9851_DICDI Probable serine/threonine-protein kinase D... 149 2e-034
sp|O01700|DLK1_CAEEL Mitogen-activated protein kinase kinase kin... 146 1e-033
>sp|Q05609|CTR1_ARATH Serine/threonine-protein kinase CTR1 OS=Arabidopsis
thaliana GN=CTR1 PE=1 SV=1
Length = 821
Score = 359 bits (919), Expect = 1e-097
Identities = 174/271 (64%), Positives = 212/271 (78%), Gaps = 2/271 (0%)
Frame = -3
Query: 1037 DVADCEIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGI 858
D D +I W D+ I E+IG GS+G V+R +WHG++VAVK ++Q+ E + EF EV I
Sbjct: 540 DGDDMDIPWCDLNIKEKIGAGSFGTVHRAEWHGSDVAVKILMEQDFHAERVNEFLREVAI 599
Query: 857 MKRVRHPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIHR--PNNQLDIRRRMRIALDAA 684
MKR+RHPN+VLFMGAVT+ P+LSIVTE+L RGSLYRL+H+ QLD RRR+ +A D A
Sbjct: 600 MKRLRHPNIVLFMGAVTQPPNLSIVTEYLSRGSLYRLLHKSGAREQLDERRRLSMAYDVA 659
Query: 683 RGMNYLHNCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMA 504
+GMNYLHN P IVHRDLKSPNLLVDK + VKVCDFGLSR+K STFLSS+S AGT EWMA
Sbjct: 660 KGMNYLHNRNPPIVHRDLKSPNLLVDKKYTVKVCDFGLSRLKASTFLSSKSAAGTPEWMA 719
Query: 503 PEVLRNEPSDEKCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPA 324
PEVLR+EPS+EK DVYSFGVILWEL TLQQPWG +NP QVV AVGF+ +RL+IP +++P
Sbjct: 720 PEVLRDEPSNEKSDVYSFGVILWELATLQQPWGNLNPAQVVAAVGFKCKRLEIPRNLNPQ 779
Query: 323 IGDIIRRCWQTDPRLRPTFADIMATLKPLQK 231
+ II CW +P RP+FA IM L+PL K
Sbjct: 780 VAAIIEGCWTNEPWKRPSFATIMDLLRPLIK 810
>sp|Q54TM7|DRKD_DICDI Probable serine/threonine-protein kinase drkD
OS=Dictyostelium discoideum GN=drkD PE=2 SV=1
Length = 1288
Score = 242 bits (617), Expect = 1e-062
Identities = 117/269 (43%), Positives = 173/269 (64%), Gaps = 3/269 (1%)
Frame = -3
Query: 1049 VSLDDVADCEIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKS 870
+ ++ + E+ +I IG RIG G YG+V+RG W GTEVAVK + + ++ + + +
Sbjct: 836 IEVEKPFEWEVPLSEIAIGARIGRGGYGQVFRGSWRGTEVAVKMLFNDNVNLKLISDLRK 895
Query: 869 EVGIMKRVRHPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALD 690
EV ++ ++RHPN+VLFMGA T IVTE+L RGSL ++ + ++D R+++ D
Sbjct: 896 EVDLLCKLRHPNIVLFMGACTEPSSPCIVTEYLSRGSLANILLDESIEMDWGLRLQLGFD 955
Query: 689 AARGMNYLHNCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEW 510
ARGM YLH+ P+I+HRDLK+ NLLVD +W VKV DFGL+ +K TF +++ GT W
Sbjct: 956 CARGMTYLHSRNPIIIHRDLKTDNLLVDDSWQVKVADFGLATVKSHTF--AKTMCGTTGW 1013
Query: 509 MAPEVLRNEPSDEKCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVD 330
+APEVL E EK DVYS+ ++LWEL T P+ G N MQVV ++ + RL +P
Sbjct: 1014 VAPEVLAEEGYTEKADVYSYAIVLWELLTRLIPYAGKNTMQVVRSID-RGERLPMPAWCP 1072
Query: 329 PAIGDIIRRCWQTDPRLRPTFADIMATLK 243
P ++ RCW+TDP RP+F +I+ ++
Sbjct: 1073 PKYAALMNRCWETDPTHRPSFPEILPIME 1101
>sp|Q54H46|DRKA_DICDI Probable serine/threonine-protein kinase drkA
OS=Dictyostelium discoideum GN=drkA PE=3 SV=1
Length = 642
Score = 236 bits (600), Expect = 1e-060
Identities = 120/262 (45%), Positives = 166/262 (63%), Gaps = 2/262 (0%)
Frame = -3
Query: 1022 EIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKRVR 843
+I I IG RIG G+YGEVY G W G++VAVKK I L+EF E+ +MK +R
Sbjct: 368 DIDIHQIKIGVRIGKGNYGEVYLGTWRGSQVAVKKLPAHNINENILKEFHREINLMKNLR 427
Query: 842 HPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLH 663
HPNV+ F+G+ P + I TE++PRGSLY ++H QL +++ +DAA+G+ YLH
Sbjct: 428 HPNVIQFLGSCLIPPDICICTEYMPRGSLYSILHDQALQLQWSLLIKMMIDAAKGVIYLH 487
Query: 662 NCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLRNE 483
N TPVI+HRDLKS NLLVD+NW VKV DFGLS ++ ++ + GT W +PEVLR++
Sbjct: 488 NSTPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQG--ATMTACGTPCWTSPEVLRSQ 545
Query: 482 PSDEKCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIRR 303
EK DVYSFG+ILWE T Q P+ G+ P QV+ AVG + R +P++ P ++
Sbjct: 546 RYTEKADVYSFGIILWECATRQDPYFGIPPFQVIFAVGREGMRPPVPQNGPPKYIQLLID 605
Query: 302 CWQTDPRLRPTFADIMATLKPL 237
C +P RPT + L+ +
Sbjct: 606 CLNENPSHRPTMEQCLERLESI 627
>sp|Q54H45|DRKB_DICDI Probable serine/threonine-protein kinase drkB
OS=Dictyostelium discoideum GN=drkB PE=3 SV=1
Length = 690
Score = 233 bits (592), Expect = 1e-059
Identities = 117/263 (44%), Positives = 166/263 (63%), Gaps = 2/263 (0%)
Frame = -3
Query: 1022 EIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKRVR 843
+I + I IG RIG G++GEVY G W G++VAVKK I L+EF E+ +MK +R
Sbjct: 385 DIDTQQIKIGVRIGKGNFGEVYLGTWRGSQVAVKKLPAHNINENILKEFHREINLMKNLR 444
Query: 842 HPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLH 663
HPNV+ F+G+ +P + I TE++PRGSLY ++H ++ R+ +DAA+G+ YLH
Sbjct: 445 HPNVIQFLGSCLISPDICICTEYMPRGSLYSILHNEKIKISWSLVKRMMIDAAKGIIYLH 504
Query: 662 NCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLRNE 483
TPVI+HRDLKS NLLVD+NW VKV DFGLS ++ ++ + GT W +PEVLR++
Sbjct: 505 GSTPVILHRDLKSHNLLVDENWKVKVADFGLSTIEQQG--ATMTACGTPCWTSPEVLRSQ 562
Query: 482 PSDEKCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIRR 303
EK DVYSFG+ILWE T Q P+ G+ P QV+ AVG + R P+ P +++
Sbjct: 563 RYTEKADVYSFGIILWECATRQDPYFGIPPFQVIFAVGREGMRPPTPKYGPPKYIQLLKD 622
Query: 302 CWQTDPRLRPTFADIMATLKPLQ 234
C +P RPT + L+ ++
Sbjct: 623 CLNENPSQRPTMEQCLEILESIE 645
>sp|Q54TA1|DRKC_DICDI Probable serine/threonine-protein kinase drkC
OS=Dictyostelium discoideum GN=drkC PE=3 SV=1
Length = 749
Score = 228 bits (581), Expect = 2e-058
Identities = 116/260 (44%), Positives = 160/260 (61%), Gaps = 3/260 (1%)
Frame = -3
Query: 1007 DITIGERIGLGSYGEVYRGDWHGTEVAVKKF-LDQEITVESLEEFKSEVGIMKRVRHPNV 831
+I + RIG GS EV+ G W G VA+KK L E + L E E IM ++RHPN+
Sbjct: 490 EIVVQNRIGRGSCAEVFTGTWRGIIVAIKKAKLLNEDDEDFLNELAQEATIMSQLRHPNI 549
Query: 830 VLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLHNCTP 651
F+G P + IV E++P GSLYR++H P+ LD R +ALD A+GMNYLH C P
Sbjct: 550 CQFLGTCNNPPEILIVMEYMPLGSLYRILHDPSISLDWPRMKSMALDIAKGMNYLHCCDP 609
Query: 650 VIVHRDLKSPNLLVDKNWVVKVCDFGLSR--MKHSTFLSSRSTAGTAEWMAPEVLRNEPS 477
+++HRDLKS NLLVD+++ VK+ DFGLS KH ++ + GT W APEVLRN+P
Sbjct: 610 IVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRNDPY 669
Query: 476 DEKCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIRRCW 297
EK DV+SF ++LWE+ T + P+ GM Q+V +VG R +P V +I CW
Sbjct: 670 TEKADVFSFAIVLWEIVTREDPYQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECW 729
Query: 296 QTDPRLRPTFADIMATLKPL 237
DP+ RP+F +I+ L+ +
Sbjct: 730 SEDPQQRPSFQEIVKRLEAM 749
>sp|Q7T6X2|YR826_MIMIV Putative serine/threonine-protein kinase/receptor R826
OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R826 PE=4 SV=2
Length = 1657
Score = 219 bits (557), Expect = 1e-055
Identities = 99/258 (38%), Positives = 167/258 (64%), Gaps = 3/258 (1%)
Frame = -3
Query: 1019 IAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKRVRH 840
I +++I +GE+IGLGSYG VYRG W +VA+KKF+ Q+I L + E+ +K++ H
Sbjct: 1394 INYDEIKMGEQIGLGSYGVVYRGKWKNVDVAIKKFIKQKIDENHLLGIREEIAFLKKLHH 1453
Query: 839 PNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLHN 660
PN++ +GA + P++ IVTE++ +G+L + +L+ ++++I ++ A+G++YLH+
Sbjct: 1454 PNIITMVGASLKKPNICIVTEYMAKGNLRDAMRTCTPKLEWHQKIKILVNIAKGISYLHS 1513
Query: 659 CTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLRNEP 480
P I+HRD+K N+L+D+NW VK+ DFG +R+K + +R GT W APE++RN+
Sbjct: 1514 FDPPIIHRDIKPSNILIDENWNVKIADFGFARIKEENAIMTR--CGTPCWTAPEIIRNDI 1571
Query: 479 SDEKCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIRRC 300
DEK DV+SFG+++WE+ T ++P+ G N M++ + + R IP+D ++R+C
Sbjct: 1572 YDEKVDVFSFGIVMWEVLTCKEPFIGANFMKITMDI-LEDVRPKIPQDCPEEFAKLMRKC 1630
Query: 299 WQTDPRLRPTFADIMATL 246
W RPT D++ L
Sbjct: 1631 WHAKSTKRPTMDDVIIVL 1648
>sp|Q54Y55|SHKC_DICDI Dual specificity protein kinase shkC OS=Dictyostelium
discoideum GN=shkC PE=3 SV=1
Length = 506
Score = 214 bits (543), Expect = 5e-054
Identities = 114/262 (43%), Positives = 158/262 (60%), Gaps = 3/262 (1%)
Frame = -3
Query: 1022 EIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKRVR 843
EI E+I E IG GS+G+VY+G VAVK Q +L F+ EV +M ++
Sbjct: 18 EIRPEEINFEELIGTGSFGKVYKGRCRQKAVAVKLLHKQNFDAATLSAFRKEVHLMSKIY 77
Query: 842 HPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLH 663
HPN+ LFMGA T IVTE +P+G+L L+H QL + RMR+A DAA G+N+LH
Sbjct: 78 HPNICLFMGACTIPGRCVIVTELVPKGNLETLLHDQKIQLPLYLRMRMARDAALGINWLH 137
Query: 662 NCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLS--RMKHSTFLSSRSTAGTAEWMAPEVLR 489
PV VHRD+KS NLLVD+N VK+CDFGLS + KH S GT +MAPEV+
Sbjct: 138 ESNPVFVHRDIKSSNLLVDENMRVKICDFGLSALKQKHKMLKDQSSAKGTPLYMAPEVMM 197
Query: 488 NEPSDEKCDVYSFGVILWELCTLQQPWGGMNPMQVV-GAVGFQHRRLDIPEDVDPAIGDI 312
+ +E DVYSFG++LWE+ T ++P+ ++ AV +H R IP D ++ +
Sbjct: 198 FKEFNESSDVYSFGIVLWEILTRKEPFSHHRELEKFREAVCVKHERPPIPNDCLDSLRRL 257
Query: 311 IRRCWQTDPRLRPTFADIMATL 246
I +CW +P RP+F +I++ L
Sbjct: 258 IEKCWDKEPISRPSFKEIISAL 279
>sp|Q7T6Y2|YR831_MIMIV Putative serine/threonine-protein kinase/receptor R831
OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R831 PE=4 SV=2
Length = 1624
Score = 211 bits (535), Expect = 4e-053
Identities = 108/305 (35%), Positives = 180/305 (59%), Gaps = 5/305 (1%)
Frame = -3
Query: 1154 LNPTRDEQGGSENDVAREGDRVSDRSAGNDSTISEVSLDDVADCE--IAWEDITIGERIG 981
+N D G+ +D + ++ D D + L C I +++I+IG++IG
Sbjct: 1312 VNYNDDTDSGTADDSNYDSGKIIDIDYMADIDKEDSFLTSANMCRWIINYDEISIGKQIG 1371
Query: 980 LGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKRVRHPNVVLFMGAVTRA 801
LGSYG V+ G W G +VAVKKF+ Q+++ L EF++E+ + ++H N+V F+GA +
Sbjct: 1372 LGSYGIVFNGKWKGVDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKK 1431
Query: 800 PHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLHNCTPVIVHRDLKSP 621
P++ IVTE++ G+L ++ P+ ++ ++++ AA G++YLH+ P+IVHRD+K
Sbjct: 1432 PNICIVTEYMRMGNLRDVLKNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPA 1491
Query: 620 NLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLRNEPSDEKCDVYSFGVI 441
N+LVD+++ VK+ DFG +R+K +R GT W APEV+R E EK DV+SFGV+
Sbjct: 1492 NILVDEHFNVKIADFGFARIKEDNTTMTR--CGTPCWTAPEVIRGEKYCEKADVFSFGVV 1549
Query: 440 LWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIRRCWQTDPRLRPTFAD 261
+WE+ T ++P+ N M+V + + R IP D +I++CW RPT +
Sbjct: 1550 MWEVLTGKEPFAECNFMKVSLDI-LEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTE 1608
Query: 260 IMATL 246
++ L
Sbjct: 1609 VVQQL 1613
Score = 206 bits (522), Expect = 1e-051
Identities = 116/272 (42%), Positives = 166/272 (61%), Gaps = 15/272 (5%)
Frame = -3
Query: 1028 DCEIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKR 849
D EI + ++ IGE +G G YGEVY+ W GTEVAVK + ++ + F EV IM
Sbjct: 778 DWEIDFSELEIGETLGTGGYGEVYKSIWKGTEVAVKLISSKHVSKDMERSFFEEVKIMTS 837
Query: 848 VRHPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLI-HRPNNQLDIRRRMRIALDAARGMN 672
+RHPNVVLFM A T++P++ IV EF+ GSLY L+ + ++ ++++A A++GM+
Sbjct: 838 LRHPNVVLFMAASTKSPNMCIVMEFMSLGSLYDLLGNELIPEIPYALKIKMAYQASKGMH 897
Query: 671 YLHNCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRST----AGTAEWMA 504
+LH+ IVHRDLKS NLL+D W VKV DFGL+++K L + T GT W+A
Sbjct: 898 FLHSSG--IVHRDLKSLNLLLDSKWNVKVSDFGLTKVKSE--LDKKKTNDNIIGTIHWIA 953
Query: 503 PEVLRNEPSDE--KCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVD 330
PE+L + + DVYSFG+ILWEL T +QP+ GM P + +V R I ++
Sbjct: 954 PEILNDSTEVDYILADVYSFGIILWELLTREQPYKGMTPAAIAVSVIRDGMRPPISDEAV 1013
Query: 329 PAIG----DIIRRCWQTDPRLRPTFADIMATL 246
A D+I++CW +D +RPTF +IM L
Sbjct: 1014 TAHSIEYIDLIKQCWHSDTIIRPTFLEIMTRL 1045
>sp|Q54U31|SHKD_DICDI Dual specificity protein kinase shkD OS=Dictyostelium
discoideum GN=shkD PE=3 SV=1
Length = 744
Score = 204 bits (518), Expect = 4e-051
Identities = 114/265 (43%), Positives = 163/265 (61%), Gaps = 5/265 (1%)
Frame = -3
Query: 1022 EIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKRVR 843
EI E+I + +G GS+G VY+G G EVAVK Q++++ L F+ EV IM ++
Sbjct: 271 EILPEEIDRTDFLGQGSFGSVYKGKCRGQEVAVKIPRKQKLSLYELTSFRHEVKIMSKIF 330
Query: 842 HPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIH--RPNNQLDIRRRMRIALDAARGMNY 669
HPNVVLF+GA T++ + IVTE L + L +L+H R + + RRM++A DAA GMN+
Sbjct: 331 HPNVVLFLGACTQSGKMQIVTE-LCQTDLEKLLHNDRTKKEFSLFRRMQMAKDAALGMNW 389
Query: 668 LHNCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLR 489
LH T IVH DLK+ NLLVD N VKV DFG S++K ++ GT WMAPEV+
Sbjct: 390 LHGITR-IVHNDLKTANLLVDINLRVKVTDFGFSQIKEGEEFQDKAAKGTPLWMAPEVMM 448
Query: 488 NEPSDEKCDVYSFGVILWELCTLQQPWGGMNPMQV-VGAVGFQHRRLDIPEDVDPAIGDI 312
P +EK DVYSFG+ILWE+ T + P+ + A+ + R IP D P++ +
Sbjct: 449 GNPYNEKADVYSFGIILWEILTKEAPYSHHKDYDIFFNAICNEKERPPIPADTLPSLRHL 508
Query: 311 IRRCWQTDPRLRPTFADIMATLKPL 237
I+ CW +P+ RP+F++I+ L +
Sbjct: 509 IQTCWDHNPQNRPSFSEILFRLNEI 533
>sp|Q5UQG7|YR818_MIMIV Putative serine/threonine-protein kinase/receptor R818
OS=Acanthamoeba polyphaga mimivirus GN=MIMI_R818 PE=4 SV=1
Length = 1651
Score = 204 bits (518), Expect = 4e-051
Identities = 103/263 (39%), Positives = 163/263 (61%), Gaps = 9/263 (3%)
Frame = -3
Query: 1019 IAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKRVRH 840
I ++DI IG++IG+GSYG V G W VAVKKF+ Q+I + + EF++E+ + ++RH
Sbjct: 1389 INYDDIQIGKQIGVGSYGIVNMGKWKNINVAVKKFVKQKIDEKQMLEFRAEIAFLSQLRH 1448
Query: 839 PNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIH--RPNNQLDIRRRMRIALDAARGMNYL 666
P+++L +GA + P++ IVTEF+ GSL +I +P +L I+ + AL G+ YL
Sbjct: 1449 PHIILMIGACLKRPNICIVTEFMGNGSLRNVIKTTKPEWKLKIKMLYQTAL----GIGYL 1504
Query: 665 HNCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLRN 486
HN P+I+HRD+K N+LVD + VK+ DFG +R+K + +R GT W APE++R
Sbjct: 1505 HNSDPIIIHRDIKPSNILVDDSMNVKIADFGFARIKEENSVMTR--CGTPCWTAPEIIRG 1562
Query: 485 EPSDEKCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIR 306
E EK DV+SFG+++WE+ T ++P+ G N M+V + + R IP D +++
Sbjct: 1563 EKYTEKVDVFSFGIVMWEVLTCKEPFSGCNFMKVSMDI-LEGARPQIPSDCPIDFTKLMK 1621
Query: 305 RCWQTDPRLRPTFADIMATLKPL 237
+CW P RP+ D++ L +
Sbjct: 1622 QCWHAKPDKRPSMEDVIMGLNDM 1644
Score = 177 bits (448), Expect = 5e-043
Identities = 100/235 (42%), Positives = 146/235 (62%), Gaps = 8/235 (3%)
Frame = -3
Query: 1022 EIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKRVR 843
E+ + ++ E +G G GEV++ W GTEVAVKK ++ IT ++ FK E+ M +R
Sbjct: 787 EVDFHELDFMESLGSGGSGEVFKAMWKGTEVAVKKLVNSNITKDAERNFKQEIHRMTSLR 846
Query: 842 HPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLI-HRPNNQLDIRRRMRIALDAARGMNYL 666
HPNVVLFM A TR P++ IV EF+ GSLY L+ + ++ R+RIA AA+GM++L
Sbjct: 847 HPNVVLFMAASTRPPNMCIVMEFMSLGSLYDLLGNELVTEIPPVLRIRIAYQAAKGMHFL 906
Query: 665 HNCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHST---FLSSRSTAGTAEWMAPEV 495
H+ IVHRDLKS NLL+D W VKV DFGL+++K + + + + +W APEV
Sbjct: 907 HSSD--IVHRDLKSLNLLLDSKWNVKVSDFGLTKIKDNNKGKSSTKEDSVCSIQWTAPEV 964
Query: 494 LRNEPSDE--KCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPED 336
L + + DVYSFG+I+WEL T +P+ G++P + AV + R +I E+
Sbjct: 965 LSEKQDIDYILADVYSFGIIMWELMTRLRPYIGLSPAAIAVAVIRDNLRPEIQEE 1019
>sp|Q54RB7|SHKA_DICDI Dual specificity protein kinase shkA OS=Dictyostelium
discoideum GN=shkA PE=2 SV=1
Length = 527
Score = 198 bits (501), Expect = 4e-049
Identities = 109/266 (40%), Positives = 165/266 (62%), Gaps = 5/266 (1%)
Frame = -3
Query: 1022 EIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFLDQEITVESLEEFKSEVGIMKRVR 843
EI+ +IT +G GS+G VY+G +VAVK L Q + ++L +F+ EV IM ++
Sbjct: 39 EISETEITTESILGDGSFGTVYKGRCRLKDVAVKVMLKQ-VDQKTLTDFRKEVAIMSKIF 97
Query: 842 HPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLH 663
HPN+VLF+GA T P ++ L +G+L L+ P +L + RMR+A DAA G+ +LH
Sbjct: 98 HPNIVLFLGACTSTPGKLMICTELMKGNLESLLLDPMVKLPLITRMRMAKDAALGVLWLH 157
Query: 662 NCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMK---HSTFLSSRSTAGTAEWMAPEVL 492
+ PV +HRDLK+ NLLVD N VKVCDFGLS++K + GT WMAPEVL
Sbjct: 158 SSNPVFIHRDLKTSNLLVDANLTVKVCDFGLSQIKQRGENLKDGQDGAKGTPLWMAPEVL 217
Query: 491 RNEPSDEKCDVYSFGVILWELCTLQQPWGGM-NPMQVVGAVGFQHRRLDIPEDVDPAIGD 315
+ +EK DVYSFG++LW++ T Q+ + N + V A+ + R IP+D ++ +
Sbjct: 218 QGRLFNEKADVYSFGLVLWQIFTRQELFPEFDNFFKFVAAICEKQLRPSIPDDCPKSLKE 277
Query: 314 IIRRCWQTDPRLRPTFADIMATLKPL 237
+I++CW +P +RP+F I++ L+ +
Sbjct: 278 LIQKCWDPNPEVRPSFEGIVSELEEI 303
>sp|Q2MHE4|HT1_ARATH Serine/threonine-protein kinase HT1 OS=Arabidopsis thaliana
GN=HT1 PE=1 SV=1
Length = 390
Score = 189 bits (478), Expect = 2e-046
Identities = 99/257 (38%), Positives = 154/257 (59%), Gaps = 8/257 (3%)
Frame = -3
Query: 998 IGERIGLGSYGEVYRGDWHGTEVAVKKFL----DQEITVESLEEFKSEVGIMKRVRHPNV 831
IG + G++ +YRG + VAVK +E + ++FKSEV ++ R+ HPN+
Sbjct: 88 IGNKFASGAHSRIYRGIYKQRAVAVKMVRIPTHKEETRAKLEQQFKSEVALLSRLFHPNI 147
Query: 830 VLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRPN-NQLDIRRRMRIALDAARGMNYLHNCT 654
V F+ A + P I+TE++ +G+L +++ L I +R+ALD +RGM YLH +
Sbjct: 148 VQFIAACKKPPVYCIITEYMSQGNLRMYLNKKEPYSLSIETVLRLALDISRGMEYLH--S 205
Query: 653 PVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLRNEPSD 474
++HRDLKS NLL++ VKV DFG S ++ + ++ GT WMAPE+++ +P
Sbjct: 206 QGVIHRDLKSNNLLLNDEMRVKVADFGTSCLE-TQCREAKGNMGTYRWMAPEMIKEKPYT 264
Query: 473 EKCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIRRCWQ 294
K DVYSFG++LWEL T P+ GM P+Q AV ++ R +P PA+ +I+RCW
Sbjct: 265 RKVDVYSFGIVLWELTTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWS 324
Query: 293 TDPRLRPTFADIMATLK 243
+P RP F++I+A L+
Sbjct: 325 ENPSKRPDFSNIVAVLE 341
>sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 OS=Homo
sapiens GN=MAP3K12 PE=1 SV=2
Length = 859
Score = 163 bits (410), Expect = 1e-038
Identities = 89/247 (36%), Positives = 143/247 (57%), Gaps = 9/247 (3%)
Frame = -3
Query: 971 YGEVYRGDWHGT----EVAVKKFLDQEITVESLEEFK-SEVGIMKRVRHPNVVLFMGAVT 807
+ E+ W G+ V + +F +E+ V+ + + K +++ +++++HPN++ F G T
Sbjct: 122 FEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCT 181
Query: 806 RAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLHNCTPVIVHRDLK 627
+AP I+ EF +G LY ++ R + + ++ A GMNYLH I+HRDLK
Sbjct: 182 QAPCYCILMEFCAQGQLYEVL-RAGRPVTPSLLVDWSMGIAGGMNYLH--LHKIIHRDLK 238
Query: 626 SPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLRNEPSDEKCDVYSFG 447
SPN+L+ + VVK+ DFG S+ + S + S AGT WMAPEV+RNEP EK D++SFG
Sbjct: 239 SPNMLITYDDVVKISDFGTSK-ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFG 297
Query: 446 VILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIRRCWQTDPRLRPTF 267
V+LWEL T + P+ ++ ++ VG L +P ++R+CW + PR RP+F
Sbjct: 298 VVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSF 357
Query: 266 ADIMATL 246
I+ L
Sbjct: 358 RQILLHL 364
>sp|Q60700|M3K12_MOUSE Mitogen-activated protein kinase kinase kinase 12 OS=Mus
musculus GN=Map3k12 PE=1 SV=1
Length = 888
Score = 163 bits (410), Expect = 1e-038
Identities = 89/247 (36%), Positives = 143/247 (57%), Gaps = 9/247 (3%)
Frame = -3
Query: 971 YGEVYRGDWHGT----EVAVKKFLDQEITVESLEEFK-SEVGIMKRVRHPNVVLFMGAVT 807
+ E+ W G+ V + +F +E+ V+ + + K +++ +++++HPN++ F G T
Sbjct: 155 FEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCT 214
Query: 806 RAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLHNCTPVIVHRDLK 627
+AP I+ EF +G LY ++ R + + ++ A GMNYLH I+HRDLK
Sbjct: 215 QAPCYCILMEFCAQGQLYEVL-RAGRPVTPSLLVDWSMGIAGGMNYLH--LHKIIHRDLK 271
Query: 626 SPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLRNEPSDEKCDVYSFG 447
SPN+L+ + VVK+ DFG S+ + S + S AGT WMAPEV+RNEP EK D++SFG
Sbjct: 272 SPNMLITYDDVVKISDFGTSK-ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFG 330
Query: 446 VILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIRRCWQTDPRLRPTF 267
V+LWEL T + P+ ++ ++ VG L +P ++R+CW + PR RP+F
Sbjct: 331 VVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNSKPRNRPSF 390
Query: 266 ADIMATL 246
I+ L
Sbjct: 391 RQILLHL 397
>sp|Q63796|M3K12_RAT Mitogen-activated protein kinase kinase kinase 12 OS=Rattus
norvegicus GN=Map3k12 PE=1 SV=1
Length = 888
Score = 162 bits (408), Expect = 2e-038
Identities = 89/247 (36%), Positives = 142/247 (57%), Gaps = 9/247 (3%)
Frame = -3
Query: 971 YGEVYRGDWHGT----EVAVKKFLDQEITVESLEEFK-SEVGIMKRVRHPNVVLFMGAVT 807
+ E+ W G+ V + +F +E+ V+ + + K +++ +++++HPN++ F G T
Sbjct: 155 FEEILDLQWVGSGAQGAVFLGRFHGEEVAVKKVRDLKETDIKHLRKLKHPNIITFKGVCT 214
Query: 806 RAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMNYLHNCTPVIVHRDLK 627
+AP I+ EF +G LY ++ R + + ++ A GMNYLH I+HRDLK
Sbjct: 215 QAPCYCILMEFCAQGQLYEVL-RAGRPVTPSLLVDWSMGIAGGMNYLH--LHKIIHRDLK 271
Query: 626 SPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVLRNEPSDEKCDVYSFG 447
SPN+L+ + VVK+ DFG S+ + S + S AGT WMAPEV+RNEP EK D++SFG
Sbjct: 272 SPNMLITYDDVVKISDFGTSK-ELSDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFG 330
Query: 446 VILWELCTLQQPWGGMNPMQVVGAVGFQHRRLDIPEDVDPAIGDIIRRCWQTDPRLRPTF 267
V+LWEL T + P+ ++ ++ VG L +P ++R+CW PR RP+F
Sbjct: 331 VVLWELLTGEIPYKDVDSSAIIWGVGSNSLHLPVPSSCPDGFKILLRQCWNRKPRNRPSF 390
Query: 266 ADIMATL 246
I+ L
Sbjct: 391 RQILLHL 397
>sp|A8X775|DLK1_CAEBR Mitogen-activated protein kinase kinase kinase dlk-1
OS=Caenorhabditis briggsae GN=dlk-1 PE=3 SV=1
Length = 857
Score = 150 bits (378), Expect = 7e-035
Identities = 75/222 (33%), Positives = 130/222 (58%), Gaps = 4/222 (1%)
Frame = -3
Query: 920 KFLDQEITVESLEEFK-SEVGIMKRVRHPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLI 744
++ ++ + V+ + + K +E+ ++ +RH N++ F+G +++P IV E+ P+G L ++
Sbjct: 80 QYENRTVAVKKVNQLKETEIKHLRHLRHKNIIEFLGVCSKSPCYCIVMEYCPKGQLCTVL 139
Query: 743 HRPNNQLDIRRRMRIALDAARGMNYLHNCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSR 564
R N + + + A GM+YLH ++HRDLKSPN+L+ +K+CDFG S
Sbjct: 140 -RQKNLITRQMFSDWVKEIADGMHYLHQ--NKVIHRDLKSPNILISAEDSIKICDFGTSH 196
Query: 563 MKHSTFLSSRSTAGTAEWMAPEVLRNEPSDEKCDVYSFGVILWELCTLQQPWGGMNPMQV 384
++ + S GT WMAPE+++ EP +EK DVYSFGV+LWE+ T + P+ + M +
Sbjct: 197 LQKKNDSTMMSFCGTVSWMAPEMIKKEPCNEKVDVYSFGVVLWEMLTRETPYANIAQMAI 256
Query: 383 VGAVGFQHRRLDIPEDVDPAIGDIIRRCWQTDPRLRPTFADI 258
+ VG L +PE+ + +I++C R RP+F+ I
Sbjct: 257 IFGVGTNILNLPMPEEAPRGLVLLIKQCLSQKGRNRPSFSHI 298
>sp|Q869X3|Y9851_DICDI Probable serine/threonine-protein kinase DDB_G0275165
OS=Dictyostelium discoideum GN=DDB_G0275165 PE=3 SV=1
Length = 921
Score = 149 bits (374), Expect = 2e-034
Identities = 91/265 (34%), Positives = 145/265 (54%), Gaps = 14/265 (5%)
Frame = -3
Query: 1022 EIAWEDITIGERIGLGSYGEVYRGDWHGTEVAVKKFL--DQEITVESLEEF-KSEVGIMK 852
EI ++ ++I IG G +G+VY+G +G E+ +KK D + + L +F + E+ +K
Sbjct: 20 EIKFDPLSI---IGSGGFGKVYQGVLNGKEIGIKKITISDNDPNRDILLKFLEREIYTLK 76
Query: 851 RVRHPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRPNNQLDIRRRMRIALDAARGMN 672
+ HPNV+ F G + L ++TE + G L+ I + + + +++IA D A M
Sbjct: 77 MLSHPNVIKFYGIAEKERSLFLLTELVSGGDLHWYIKNKSIDITWKLKVKIARDIAASMA 136
Query: 671 YLHNCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHSTFLSSRSTAGTAEWMAPEVL 492
YLH ++HRDLKS NLLV +NWV+KVCD GL+R + S + GT +WMAPEVL
Sbjct: 137 YLHE--NGVIHRDLKSTNLLVAENWVIKVCDMGLARKMDKSEKSKMTICGTDDWMAPEVL 194
Query: 491 RNEPSDEKCDVYSFGVILWELCTLQQPWGGMNPMQVVGAVGFQHRRL--DIPEDVDPAIG 318
E D CDV+SFG++L EL T + + P +G + +P D +
Sbjct: 195 IGEEYDASCDVFSFGMVLIELITRE----NLTPRIRNEDLGVDQKFFLSKVPADCPKELL 250
Query: 317 DIIRRCWQTDPRLRPTFADIMATLK 243
++ C + P RP+ ++I+ L+
Sbjct: 251 RLVSECCKVAPSGRPSASNILGLLE 275
>sp|O01700|DLK1_CAEEL Mitogen-activated protein kinase kinase kinase dlk-1
OS=Caenorhabditis elegans GN=dlk-1 PE=1 SV=4
Length = 928
Score = 146 bits (367), Expect = 1e-033
Identities = 73/219 (33%), Positives = 127/219 (57%), Gaps = 4/219 (1%)
Frame = -3
Query: 911 DQEITVESLEEFK-SEVGIMKRVRHPNVVLFMGAVTRAPHLSIVTEFLPRGSLYRLIHRP 735
++ + V+ + + K +E+ ++ +RH N++ F+G +++P IV E+ +G L ++ +
Sbjct: 156 NRTVAVKKVNQLKETEIKHLRHLRHQNIIEFLGVCSKSPCYCIVMEYCSKGQLCTVL-KS 214
Query: 734 NNQLDIRRRMRIALDAARGMNYLHNCTPVIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKH 555
N + + + A GM+YLH ++HRDLKSPN+L+ +K+CDFG S M+
Sbjct: 215 RNTITRELFAQWVKEIADGMHYLHQ--NKVIHRDLKSPNILISAEDSIKICDFGTSHMQK 272
Query: 554 STFLSSRSTAGTAEWMAPEVLRNEPSDEKCDVYSFGVILWELCTLQQPWGGMNPMQVVGA 375
+ S GT WMAPE+++ +P +EK DVYSFGV+LWE+ T + P+ + M ++
Sbjct: 273 KMDSTMMSFCGTVSWMAPEMIKKQPCNEKVDVYSFGVVLWEMLTRETPYANIAQMAIIFG 332
Query: 374 VGFQHRRLDIPEDVDPAIGDIIRRCWQTDPRLRPTFADI 258
VG L +PE+ + +I++C R RP+F+ I
Sbjct: 333 VGTNILSLPMPEEAPKGLVLLIKQCLSQKGRNRPSFSHI 371
Database: Uniprot/SwissProt
Posted date: Thu Sep 27 17:53:50 2012
Number of letters in database: 190,795,139
Number of sequences in database: 537,505
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 154,062,361,774
Number of Sequences: 537505
Number of Extensions: 154062361774
Number of Successful Extensions: 917730706
Number of sequences better than 0.0: 0
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