SwissProt blast output of UN63005
BLASTX 7.6.2
Query= UN63005 /QuerySize=1956
(1955 letters)
Database: Uniprot/SwissProt;
537,505 sequences; 190,795,139 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5ZLN0|LRC40_CHICK Leucine-rich repeat-containing protein 40 ... 179 1e-043
sp|Q5M8G4|LRC40_XENTR Leucine-rich repeat-containing protein 40 ... 178 2e-043
sp|Q6GPJ5|LRC40_XENLA Leucine-rich repeat-containing protein 40 ... 177 3e-043
sp|Q9CRC8|LRC40_MOUSE Leucine-rich repeat-containing protein 40 ... 157 3e-037
sp|Q5F4C4|SHOC2_CHICK Leucine-rich repeat protein SHOC-2 OS=Gall... 147 4e-034
sp|Q1L8Y7|SHOC2_DANRE Leucine-rich repeat protein SHOC-2 OS=Dani... 146 6e-034
sp|Q8AVI4|SHOC2_XENLA Leucine-rich repeat protein SHOC-2 OS=Xeno... 146 6e-034
sp|Q6AYI5|SHOC2_RAT Leucine-rich repeat protein SHOC-2 OS=Rattus... 144 3e-033
sp|O88520|SHOC2_MOUSE Leucine-rich repeat protein SHOC-2 OS=Mus ... 143 6e-033
sp|A6QLV3|SHOC2_BOVIN Leucine-rich repeat protein SHOC-2 OS=Bos ... 142 1e-032
sp|Q9UQ13|SHOC2_HUMAN Leucine-rich repeat protein SHOC-2 OS=Homo... 142 1e-032
sp|Q5RAV5|SHOC2_PONAB Leucine-rich repeat protein SHOC-2 OS=Pong... 142 1e-032
sp|B0W6M9|SUR8_CULQU Leucine-rich repeat protein soc-2 homolog O... 136 6e-031
sp|B3LWU3|SUR8_DROAN Leucine-rich repeat protein soc-2 homolog O... 135 2e-030
sp|B4N9T4|SUR8_DROWI Leucine-rich repeat protein soc-2 homolog O... 134 3e-030
sp|Q9VEK6|SUR8_DROME Leucine-rich repeat protein soc-2 homolog O... 133 7e-030
sp|B4IBI9|SUR8_DROSE Leucine-rich repeat protein soc-2 homolog O... 132 9e-030
sp|B4QVR7|SUR8_DROSI Leucine-rich repeat protein soc-2 homolog O... 132 9e-030
sp|B4PU77|SUR8_DROYA Leucine-rich repeat protein soc-2 homolog O... 132 9e-030
>sp|Q5ZLN0|LRC40_CHICK Leucine-rich repeat-containing protein 40 OS=Gallus
gallus GN=LRRC40 PE=2 SV=1
Length = 603
Score = 179 bits (452), Expect = 1e-043
Identities = 106/313 (33%), Positives = 174/313 (55%), Gaps = 5/313 (1%)
Frame = -2
Query: 1744 EVPDDVYKSLDAVGEGENWWEAVELQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSH 1565
+ P++ +++L + G + WWE +L KLILA N+L+ L ED+R LP L VL+V N+L+
Sbjct: 61 DTPEEAHQNL-SFGAADRWWEQTDLTKLILASNQLRCLSEDVRLLPALTVLDVHDNQLTS 119
Query: 1564 LPAAIGELKSLKALDVSNNLLREIPEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDL 1385
LP+A+G+L++L+ LDVS+N L+ IPEE+ + L L N+L LP G + L +L
Sbjct: 120 LPSALGQLENLQKLDVSHNKLKSIPEELLQLSHLKGLLLQHNELSHLPDGFGQLVSLEEL 179
Query: 1384 KASNNCLTSLPEDLSNCSKMSKLDVEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPES 1205
SNN LT +P+ + + +L++ N+L L +++ L +++ KN L +P
Sbjct: 180 DLSNNHLTDIPKSFALLINLVRLNLACNQLKDLPAD-ISAMKSLRQLDCTKNYLESVPSE 238
Query: 1204 IGCLSRLIRLDLHQNKIASVPSSIKGCSKLAEFYMGNNFLTTLPTE-IGELTTLGTFDLH 1028
+ ++ L +L L +NK+ S+P + C L E + G N + L E + L +L +L
Sbjct: 239 LASMASLEQLYLRKNKLRSLP-ELPSCKLLKELHAGENQIEILNAENLKHLNSLSVLELR 297
Query: 1027 SNKLKEYPVD-ACXXXXXXXXXXXXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSLVTG 851
NK+K P + P +G ++ L+ L L GNP+RT+R L+
Sbjct: 298 DNKIKSVPDEITLLQKLERLDLANNDISRLPYTLGNLSQLKFLALEGNPLRTIRRDLLQK 357
Query: 850 PTPALLRFLRSRL 812
T LL++LRSR+
Sbjct: 358 GTQELLKYLRSRI 370
Score = 138 bits (347), Expect = 2e-031
Identities = 91/246 (36%), Positives = 140/246 (56%), Gaps = 10/246 (4%)
Frame = -2
Query: 1744 EVPDDVYKSL-DAVGEGENWWEAVELQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLS 1568
+V D+ SL A+G+ EN LQKL ++HN+L+S+ E++ L L L + HN+LS
Sbjct: 111 DVHDNQLTSLPSALGQLEN------LQKLDVSHNKLKSIPEELLQLSHLKGLLLQHNELS 164
Query: 1567 HLPAAIGELKSLKALDVSNNLLREIPEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSD 1388
HLP G+L SL+ LD+SNN L +IP+ +L++L+ + NQLKDLP + L
Sbjct: 165 HLPDGFGQLVSLEELDLSNNHLTDIPKSFALLINLVRLNLACNQLKDLPADISAMKSLRQ 224
Query: 1387 LKASNNCLTSLPEDLSNCSKMSKLDVEGNKLTVLSERLVASWTLLTEVNAAKNALSGI-P 1211
L + N L S+P +L++ + + +L + NKL L E + S LL E++A +N + +
Sbjct: 225 LDCTKNYLESVPSELASMASLEQLYLRKNKLRSLPE--LPSCKLLKELHAGENQIEILNA 282
Query: 1210 ESIGCLSRLIRLDLHQNKIASVPSSIKGCSKLAEFYMGNNFLTTLPTEIGELTTLGTFDL 1031
E++ L+ L L+L NKI SVP I KL + NN ++ LP +G L+ L L
Sbjct: 283 ENLKHLNSLSVLELRDNKIKSVPDEITLLQKLERLDLANNDISRLPYTLGNLSQLKFLAL 342
Query: 1030 HSNKLK 1013
N L+
Sbjct: 343 EGNPLR 348
>sp|Q5M8G4|LRC40_XENTR Leucine-rich repeat-containing protein 40 OS=Xenopus
tropicalis GN=lrrc40 PE=2 SV=1
Length = 605
Score = 178 bits (450), Expect = 2e-043
Identities = 104/313 (33%), Positives = 173/313 (55%), Gaps = 5/313 (1%)
Frame = -2
Query: 1744 EVPDDVYKSLDAVGEGENWWEAVELQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSH 1565
+ P + ++++D G + WWE +L KLILA N+LQ L EDI LP L VL++ N++
Sbjct: 61 DTPPEAHQNVD-FGGSDRWWEQTDLTKLILASNKLQLLSEDISLLPALVVLDIHDNQIVS 119
Query: 1564 LPAAIGELKSLKALDVSNNLLREIPEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDL 1385
LP AI EL +L+ L++S+N ++++P+E+ +L L NQL++LP S+G+ L +L
Sbjct: 120 LPCAIKELTNLQKLNISHNKIKQLPKELQHLQNLKSLLLQHNQLEELPDSIGHLSILEEL 179
Query: 1384 KASNNCLTSLPEDLSNCSKMSKLDVEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPES 1205
SNNCL S+ + + + K ++ NKLT L + L +++ N L +P S
Sbjct: 180 DVSNNCLRSISSSVGQLTGLVKFNLSSNKLTALPTE-IGKMKNLKQLDCTSNLLENVPAS 238
Query: 1204 IGCLSRLIRLDLHQNKIASVPSSIKGCSKLAEFYMGNNFLTTL-PTEIGELTTLGTFDLH 1028
+ + L +L L QNK+ +P + +KL E ++GNN + TL P + L++L +L
Sbjct: 239 VAGMESLEQLYLRQNKLTYLP-ELPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELR 297
Query: 1027 SNKLKEYPVD-ACXXXXXXXXXXXXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSLVTG 851
NKLK P + + P +G + +L+ L L GNP+R +R ++
Sbjct: 298 YNKLKVLPEEISLLNGLERLDLSNNDLGSLPCTLGSLPNLKSLQLEGNPLRGIRRDILNK 357
Query: 850 PTPALLRFLRSRL 812
T LL++L+ R+
Sbjct: 358 GTQELLKYLKGRV 370
>sp|Q6GPJ5|LRC40_XENLA Leucine-rich repeat-containing protein 40 OS=Xenopus
laevis GN=lrrc40 PE=2 SV=1
Length = 605
Score = 177 bits (448), Expect = 3e-043
Identities = 103/313 (32%), Positives = 173/313 (55%), Gaps = 5/313 (1%)
Frame = -2
Query: 1744 EVPDDVYKSLDAVGEGENWWEAVELQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSH 1565
+ P + ++++D G + WWE +L KLILA N+LQ+L EDI LP L VL++ N+++
Sbjct: 61 DTPPEAHQNVD-FGGSDRWWEQTDLTKLILASNKLQALSEDISLLPALVVLDIHDNQIAS 119
Query: 1564 LPAAIGELKSLKALDVSNNLLREIPEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDL 1385
LP AI EL +L+ L++S+N ++++P E+ +L NQL++LP S+G+ L +L
Sbjct: 120 LPCAIRELTNLQKLNISHNKIKQLPNELQHLQNLKSFLLQHNQLEELPDSIGHLSILEEL 179
Query: 1384 KASNNCLTSLPEDLSNCSKMSKLDVEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPES 1205
SNNCL S+ + + + K ++ NKLT L + L +++ N L +P S
Sbjct: 180 DVSNNCLRSVSSSVGQLTGLVKFNLSSNKLTALPTE-IGKMKNLRQLDCTSNLLENVPAS 238
Query: 1204 IGCLSRLIRLDLHQNKIASVPSSIKGCSKLAEFYMGNNFLTTL-PTEIGELTTLGTFDLH 1028
+ + L +L L QNK+ +P + +KL E ++GNN + TL P + L++L +L
Sbjct: 239 VAGMESLEQLYLRQNKLTYLP-ELPFLTKLKELHVGNNQIQTLGPEHLQNLSSLSVLELR 297
Query: 1027 SNKLKEYPVD-ACXXXXXXXXXXXXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSLVTG 851
NKLK P + + P +G + +L+ L L GNP+R +R ++
Sbjct: 298 YNKLKVLPKEISLLKGLERLDLSNNDIGSLPDTLGSLPNLKSLQLDGNPLRGIRRDILNK 357
Query: 850 PTPALLRFLRSRL 812
T LL++L+ R+
Sbjct: 358 GTQELLKYLKGRV 370
>sp|Q9CRC8|LRC40_MOUSE Leucine-rich repeat-containing protein 40 OS=Mus musculus
GN=Lrrc40 PE=2 SV=2
Length = 602
Score = 157 bits (396), Expect = 3e-037
Identities = 98/313 (31%), Positives = 167/313 (53%), Gaps = 6/313 (1%)
Frame = -2
Query: 1744 EVPDDVYKSLDAVGEGENWWEAVELQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSH 1565
++P++ ++L + E WW+ +L KLI++ N+LQSL +D+R LP L VL++ N+L+
Sbjct: 61 DIPEEANQNL-SFSSTERWWDQTDLTKLIISSNKLQSLSDDLRLLPALTVLDIHDNQLTS 119
Query: 1564 LPAAIGELKSLKALDVSNNLLREIPEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDL 1385
LP+AI EL +L+ L+VS+N L+ +PEE+ S +L L N+L +P + L DL
Sbjct: 120 LPSAIRELDNLQKLNVSHNKLKILPEEITSLKNLRTLHLQHNELTCIPEGFEHLSCLEDL 179
Query: 1384 KASNNCLTSLPEDLSNCSKMSKLDVEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPES 1205
S+N L ++P D + S + +L++ N+L L ++ L ++ N L +P
Sbjct: 180 DLSSNRLATVPADFALLSSLLRLNLSSNQLKNLPAE-ISRMKRLKHLDCDANLLETVPPD 238
Query: 1204 IGCLSRLIRLDLHQNKIASVPSSIKGCSKLAEFYMGNNFLTTLPTE-IGELTTLGTFDLH 1028
+G + L L L +NK+ +P C +L E ++ N + L E + L + DL
Sbjct: 239 VGSMESLELLYLRRNKLRVLP-EFPSCRQLKELHLAENQIEKLGAEHLQHLQAILVLDLR 297
Query: 1027 SNKLKEYPVD-ACXXXXXXXXXXXXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSLVTG 851
NKL+ P + A P +G + L+ L L GNP+RT+R ++
Sbjct: 298 GNKLRSVPEEMALLQSLERLDLSNNDISSLPCSLGNL-HLKFLALEGNPLRTIRREIIAK 356
Query: 850 PTPALLRFLRSRL 812
T +L++LRS++
Sbjct: 357 GTQEVLKYLRSKI 369
>sp|Q5F4C4|SHOC2_CHICK Leucine-rich repeat protein SHOC-2 OS=Gallus gallus
GN=SHOC2 PE=2 SV=1
Length = 529
Score = 147 bits (369), Expect = 4e-034
Identities = 90/279 (32%), Positives = 148/279 (53%), Gaps = 3/279 (1%)
Frame = -2
Query: 1687 WEAVELQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNN 1508
+ L L L N + ++++DI+ L L +L++ NK+ LPA IGEL +L LDV++N
Sbjct: 189 YRLTSLATLYLRFNRITTVEKDIKTLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHN 248
Query: 1507 LLREIPEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSK 1328
L +PEE+GS T + LD N+L DLP ++GN LS L N L+++P+ L+ CS+
Sbjct: 249 QLEHLPEEIGSCTQITNLDLQHNELLDLPETIGNLSSLSRLGLRYNRLSAIPKSLAKCSE 308
Query: 1327 MSKLDVEGNKLTVLSERLVASWTLLTEVNAAKNALSGIP-ESIGCLSRLIRLDLHQNKIA 1151
+ +L++E N ++ L E L++S LT + A+N P S + L++ N+I
Sbjct: 309 LDELNLENNNISTLPEGLLSSLVKLTSLTLARNCFQSYPVGGPSQFSTIYSLNMEHNRIN 368
Query: 1150 SVPSSIKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXX 977
+P I +K L++ M +N LT+LP + G T++ +L +N+L + P D
Sbjct: 369 KIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLE 428
Query: 976 XXXXXXXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSL 860
P IG + LR L L N + +L + +
Sbjct: 429 VLILSNNLLKKLPHGIGNLRKLRELDLEENKLESLPNEI 467
>sp|Q1L8Y7|SHOC2_DANRE Leucine-rich repeat protein SHOC-2 OS=Danio rerio
GN=shoc2 PE=2 SV=1
Length = 561
Score = 146 bits (368), Expect = 6e-034
Identities = 88/274 (32%), Positives = 147/274 (53%), Gaps = 3/274 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++++DI+NL L +L++ NK+ LPA IGEL +L LDV++N L +
Sbjct: 173 LTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHL 232
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
P+E+G+ T + LD N L DLP ++GN ++ L N L+++P L+ C ++ +L+
Sbjct: 233 PKEIGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELN 292
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIP-ESIGCLSRLIRLDLHQNKIASVPSS 1136
+E N ++VL E L++S LT + A+N P S + L++ N+I +P
Sbjct: 293 LENNNISVLPEGLLSSLVNLTSLTLARNCFQSYPVGGPSQFSTIYSLNMEHNRINKIPFG 352
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L++ M +N LT+LP + G T++ +L +N+L + P D C
Sbjct: 353 IFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDICGLVSLEMLTLS 412
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSL 860
P IG + LR L L N + +L + +
Sbjct: 413 NNLLKKLPYGIGNLRKLRELDLEENKLESLPNEI 446
>sp|Q8AVI4|SHOC2_XENLA Leucine-rich repeat protein SHOC-2 OS=Xenopus laevis
GN=shoc2 PE=2 SV=1
Length = 577
Score = 146 bits (368), Expect = 6e-034
Identities = 88/274 (32%), Positives = 147/274 (53%), Gaps = 3/274 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++++D++ LP L +L++ NK+ HLPA IGEL +L LDV++N L +
Sbjct: 189 LTTLFLRFNRITAVEKDLKMLPKLTMLSIRENKIKHLPAEIGELCNLITLDVAHNQLEHL 248
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
P+E+G+ T + LD N+L DLP ++GN LS L N L+++P LS CS++ +L+
Sbjct: 249 PKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAVPRSLSKCSELDELN 308
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIP-ESIGCLSRLIRLDLHQNKIASVPSS 1136
+E N ++ L E L++S + + A+N P S + L++ N+I +P
Sbjct: 309 LENNNISTLPEGLLSSLVKVNSLTLARNCFQSYPVGGPSQFSSIYSLNMEHNRINKIPFG 368
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L++ M +N LT+LP + G T++ +L +N+L + P D
Sbjct: 369 IFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSIEVLILS 428
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSL 860
P IG + LR L L N + +L + +
Sbjct: 429 NNLLKKLPHGIGNLRKLRELDLEENKLESLPNEI 462
>sp|Q6AYI5|SHOC2_RAT Leucine-rich repeat protein SHOC-2 OS=Rattus norvegicus
GN=Shoc2 PE=2 SV=1
Length = 582
Score = 144 bits (362), Expect = 3e-033
Identities = 87/274 (31%), Positives = 146/274 (53%), Gaps = 3/274 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++++D+RNLP L+ L++ NK+ LPA IGEL +L LDV++N L +
Sbjct: 194 LTTLYLRFNRITAVEKDVRNLPRLSTLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHL 253
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
P+E+G+ T + LD N+L DLP ++GN L+ L N L+++P L+ CS + +L+
Sbjct: 254 PKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELN 313
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIP-ESIGCLSRLIRLDLHQNKIASVPSS 1136
+E N ++ L E L++S L + A+N P S + L++ N+I +P
Sbjct: 314 LENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 373
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L++ M +N LT+LP + G T++ +L +N+L + P D
Sbjct: 374 IFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILS 433
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSL 860
P +G + LR L L N + +L + +
Sbjct: 434 NNLLKKLPHGLGNLRKLRELDLEENKLESLPNEI 467
>sp|O88520|SHOC2_MOUSE Leucine-rich repeat protein SHOC-2 OS=Mus musculus
GN=Shoc2 PE=2 SV=2
Length = 582
Score = 143 bits (359), Expect = 6e-033
Identities = 87/274 (31%), Positives = 146/274 (53%), Gaps = 3/274 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++++DI+NLP L++L++ NK+ LPA IGEL +L LDV++N L +
Sbjct: 194 LTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHL 253
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
P+E+G+ T + LD N L DLP ++GN L+ L N L+++P L+ CS + +L+
Sbjct: 254 PKEIGNCTQITNLDLQHNDLLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELN 313
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIP-ESIGCLSRLIRLDLHQNKIASVPSS 1136
+E N ++ L E L++S L + A+N P S + L++ N+I +P
Sbjct: 314 LENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 373
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L++ M +N LT+LP + G T++ +L +N+L + P D
Sbjct: 374 IFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILS 433
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSL 860
P +G + LR L L N + +L + +
Sbjct: 434 NNLLKKLPHGLGNLRKLRELDLEENKLESLPNEI 467
>sp|A6QLV3|SHOC2_BOVIN Leucine-rich repeat protein SHOC-2 OS=Bos taurus GN=SHOC2
PE=2 SV=1
Length = 582
Score = 142 bits (356), Expect = 1e-032
Identities = 87/274 (31%), Positives = 146/274 (53%), Gaps = 3/274 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++++DI+NL L++L++ NK+ LPA IGEL +L LDV++N L +
Sbjct: 194 LTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHL 253
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
P+E+G+ T + LD N+L DLP ++GN LS L N L+++P L+ CS + +L+
Sbjct: 254 PKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELN 313
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIP-ESIGCLSRLIRLDLHQNKIASVPSS 1136
+E N ++ L E L++S L + A+N P S + L++ N+I +P
Sbjct: 314 LENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 373
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L++ M +N LT+LP + G T++ +L +N+L + P D
Sbjct: 374 IFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILS 433
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSL 860
P +G + LR L L N + +L + +
Sbjct: 434 NNLLKKLPHGLGNLRKLRELDLEENKLESLPNEI 467
>sp|Q9UQ13|SHOC2_HUMAN Leucine-rich repeat protein SHOC-2 OS=Homo sapiens
GN=SHOC2 PE=1 SV=2
Length = 582
Score = 142 bits (356), Expect = 1e-032
Identities = 87/274 (31%), Positives = 146/274 (53%), Gaps = 3/274 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++++DI+NL L++L++ NK+ LPA IGEL +L LDV++N L +
Sbjct: 194 LTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHL 253
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
P+E+G+ T + LD N+L DLP ++GN LS L N L+++P L+ CS + +L+
Sbjct: 254 PKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELN 313
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIP-ESIGCLSRLIRLDLHQNKIASVPSS 1136
+E N ++ L E L++S L + A+N P S + L++ N+I +P
Sbjct: 314 LENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 373
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L++ M +N LT+LP + G T++ +L +N+L + P D
Sbjct: 374 IFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILS 433
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSL 860
P +G + LR L L N + +L + +
Sbjct: 434 NNLLKKLPHGLGNLRKLRELDLEENKLESLPNEI 467
>sp|Q5RAV5|SHOC2_PONAB Leucine-rich repeat protein SHOC-2 OS=Pongo abelii
GN=SHOC2 PE=2 SV=2
Length = 582
Score = 142 bits (356), Expect = 1e-032
Identities = 87/274 (31%), Positives = 146/274 (53%), Gaps = 3/274 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++++DI+NL L++L++ NK+ LPA IGEL +L LDV++N L +
Sbjct: 194 LTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHL 253
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
P+E+G+ T + LD N+L DLP ++GN LS L N L+++P L+ CS + +L+
Sbjct: 254 PKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELN 313
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIP-ESIGCLSRLIRLDLHQNKIASVPSS 1136
+E N ++ L E L++S L + A+N P S + L++ N+I +P
Sbjct: 314 LENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFG 373
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L++ M +N LT+LP + G T++ +L +N+L + P D
Sbjct: 374 IFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILS 433
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSL 860
P +G + LR L L N + +L + +
Sbjct: 434 NNLLKKLPHGLGNLRKLRELDLEENKLESLPNEI 467
>sp|B0W6M9|SUR8_CULQU Leucine-rich repeat protein soc-2 homolog OS=Culex
quinquefasciatus GN=Sur-8 PE=3 SV=1
Length = 628
Score = 136 bits (342), Expect = 6e-031
Identities = 86/274 (31%), Positives = 142/274 (51%), Gaps = 3/274 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N ++ + ++++NL L +L++ NK+ LPAAIG L++L LD+S+N L+ +
Sbjct: 241 LTTLYLRFNRIKVVGDNLKNLSSLTMLSLRENKIHELPAAIGHLRNLTTLDLSHNHLKHL 300
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
PE +G+ +L LD N L D+P ++GN +L L N LT++P L NC M + +
Sbjct: 301 PEAIGNCVNLTALDLQHNDLLDIPETIGNLANLQRLGLRYNQLTAIPVSLRNCIHMDEFN 360
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPE-SIGCLSRLIRLDLHQNKIASVPSS 1136
VEGN ++ L + L+AS + LT + ++NA P + + +++ N+I +
Sbjct: 361 VEGNSISQLPDGLLASLSNLTTITLSRNAFHSYPSGGPAQFTNVTSINMEHNQIDKIQYG 420
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDA-CXXXXXXXXXX 962
I +K L + M N LT+LP +IG + + + +N L + P D C
Sbjct: 421 IFSRAKGLTKLNMKENALTSLPLDIGTWSQMVELNFGTNSLAKLPDDIHCLQNLEILILS 480
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTLRSSL 860
P IG + LR L L N + +L S +
Sbjct: 481 NNMLKRIPNTIGNLKKLRVLDLEENRLESLPSEI 514
>sp|B3LWU3|SUR8_DROAN Leucine-rich repeat protein soc-2 homolog OS=Drosophila
ananassae GN=Sur-8 PE=3 SV=1
Length = 641
Score = 135 bits (338), Expect = 2e-030
Identities = 90/270 (33%), Positives = 137/270 (50%), Gaps = 3/270 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++ +D+R L L +L++ NK+ L +AIG L +L LDVS+N L +
Sbjct: 254 LTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHL 313
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
PE++G+ +L LD N+L D+P S+GN L L N LTS+P L NC M + +
Sbjct: 314 PEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMRYNRLTSVPATLKNCKCMDEFN 373
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPE-SIGCLSRLIRLDLHQNKIASVPSS 1136
VEGN +T L + ++AS + LT + ++N + P + + ++L N+I +P
Sbjct: 374 VEGNGITQLPDGMLASLSGLTTITLSRNQFTSYPTGGPAQFTNVYSINLEHNRIDKIPYG 433
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L + M N LT LP +IG + +L +N L++ P D
Sbjct: 434 IFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILS 493
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTL 872
P IG + LR L L N I TL
Sbjct: 494 NNMLKKIPNTIGNLRRLRILDLEENRIETL 523
>sp|B4N9T4|SUR8_DROWI Leucine-rich repeat protein soc-2 homolog OS=Drosophila
willistoni GN=Sur-8 PE=3 SV=1
Length = 641
Score = 134 bits (336), Expect = 3e-030
Identities = 89/270 (32%), Positives = 135/270 (50%), Gaps = 3/270 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++ +D+R L L +L++ NK+ L +AIG L +L LDVS+N L +
Sbjct: 254 LTTLYLRFNRITTVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHL 313
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
PE++G+ +L LD N+L D+P S+GN L L N LTS+P L NC M + +
Sbjct: 314 PEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGLRYNRLTSVPASLKNCKSMDEFN 373
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPE-SIGCLSRLIRLDLHQNKIASVPSS 1136
VEGN +T L + ++AS LT + ++N + P + + ++L N+I +P
Sbjct: 374 VEGNGITQLPDGMLASLNGLTIITLSRNQFTSYPTGGPAQFTNVYNINLEHNRIDKIPYG 433
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L + M N LT LP +IG + +L +N L++ P D
Sbjct: 434 IFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILS 493
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTL 872
P IG + LR L L N I L
Sbjct: 494 NNMLKKIPNTIGNLRKLRILDLEENRIEVL 523
>sp|Q9VEK6|SUR8_DROME Leucine-rich repeat protein soc-2 homolog OS=Drosophila
melanogaster GN=Sur-8 PE=2 SV=3
Length = 641
Score = 133 bits (333), Expect = 7e-030
Identities = 88/270 (32%), Positives = 136/270 (50%), Gaps = 3/270 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++ +D+R L L +L++ NK+ L +AIG L +L LDVS+N L +
Sbjct: 254 LTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHL 313
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
PE++G+ +L LD N+L D+P S+GN L L N L+S+P L NC M + +
Sbjct: 314 PEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMRYNRLSSVPATLKNCKSMDEFN 373
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPE-SIGCLSRLIRLDLHQNKIASVPSS 1136
VEGN +T L + ++AS + LT + ++N + P + + ++L N+I +P
Sbjct: 374 VEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYG 433
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L + M N LT LP +IG + +L +N L++ P D
Sbjct: 434 IFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILS 493
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTL 872
P IG + LR L L N I L
Sbjct: 494 NNMLKKIPNTIGNLRKLRILDLEENRIEVL 523
>sp|B4IBI9|SUR8_DROSE Leucine-rich repeat protein soc-2 homolog OS=Drosophila
sechellia GN=Sur-8 PE=3 SV=1
Length = 683
Score = 132 bits (332), Expect = 9e-030
Identities = 88/270 (32%), Positives = 136/270 (50%), Gaps = 3/270 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++ +D+R L L +L++ NK+ L +AIG L +L LDVS+N L +
Sbjct: 257 LTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHL 316
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
PE++G+ +L LD N+L D+P S+GN L L N L+S+P L NC M + +
Sbjct: 317 PEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMRYNRLSSVPATLKNCKSMDEFN 376
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPE-SIGCLSRLIRLDLHQNKIASVPSS 1136
VEGN +T L + ++AS + LT + ++N + P + + ++L N+I +P
Sbjct: 377 VEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYG 436
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L + M N LT LP +IG + +L +N L++ P D
Sbjct: 437 IFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILS 496
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTL 872
P IG + LR L L N I L
Sbjct: 497 NNMLKKIPNTIGNLRRLRILDLEENRIEVL 526
>sp|B4QVR7|SUR8_DROSI Leucine-rich repeat protein soc-2 homolog OS=Drosophila
simulans GN=Sur-8 PE=3 SV=2
Length = 680
Score = 132 bits (332), Expect = 9e-030
Identities = 88/270 (32%), Positives = 136/270 (50%), Gaps = 3/270 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++ +D+R L L +L++ NK+ L +AIG L +L LDVS+N L +
Sbjct: 254 LTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHL 313
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
PE++G+ +L LD N+L D+P S+GN L L N L+S+P L NC M + +
Sbjct: 314 PEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMRYNRLSSVPATLKNCKSMDEFN 373
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPE-SIGCLSRLIRLDLHQNKIASVPSS 1136
VEGN +T L + ++AS + LT + ++N + P + + ++L N+I +P
Sbjct: 374 VEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYG 433
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L + M N LT LP +IG + +L +N L++ P D
Sbjct: 434 IFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILS 493
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTL 872
P IG + LR L L N I L
Sbjct: 494 NNMLKKIPNTIGNLRRLRILDLEENRIEVL 523
>sp|B4PU77|SUR8_DROYA Leucine-rich repeat protein soc-2 homolog OS=Drosophila
yakuba GN=Sur-8 PE=3 SV=1
Length = 645
Score = 132 bits (332), Expect = 9e-030
Identities = 88/270 (32%), Positives = 136/270 (50%), Gaps = 3/270 (1%)
Frame = -2
Query: 1672 LQKLILAHNELQSLKEDIRNLPLLAVLNVSHNKLSHLPAAIGELKSLKALDVSNNLLREI 1493
L L L N + ++ +D+R L L +L++ NK+ L +AIG L +L LDVS+N L +
Sbjct: 258 LTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHL 317
Query: 1492 PEEVGSATSLIKLDCSGNQLKDLPCSLGNCLDLSDLKASNNCLTSLPEDLSNCSKMSKLD 1313
PE++G+ +L LD N+L D+P S+GN L L N L+S+P L NC M + +
Sbjct: 318 PEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMRYNRLSSVPATLKNCKSMDEFN 377
Query: 1312 VEGNKLTVLSERLVASWTLLTEVNAAKNALSGIPE-SIGCLSRLIRLDLHQNKIASVPSS 1136
VEGN +T L + ++AS + LT + ++N + P + + ++L N+I +P
Sbjct: 378 VEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYG 437
Query: 1135 IKGCSK-LAEFYMGNNFLTTLPTEIGELTTLGTFDLHSNKLKEYPVDAC-XXXXXXXXXX 962
I +K L + M N LT LP +IG + +L +N L++ P D
Sbjct: 438 IFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILS 497
Query: 961 XXXXXXXPAEIGLMTSLRRLVLTGNPIRTL 872
P IG + LR L L N I L
Sbjct: 498 NNMLKKIPNTIGNLRRLRILDLEENRIEVL 527
Database: Uniprot/SwissProt
Posted date: Thu Sep 27 17:53:50 2012
Number of letters in database: 190,795,139
Number of sequences in database: 537,505
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,817,425,758
Number of Sequences: 537505
Number of Extensions: 97817425758
Number of Successful Extensions: 557193878
Number of sequences better than 0.0: 0
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